Subtyping Lung Cancer Using DNA Methylation in Liquid Biopsies

by Sandra P. Nunes, Francisca Diniz, Catarina Moreira-Barbosa, Vera Constâncio, Ana Victor Silva, Júlio Oliveira, Marta Soares, Sofia Paulino, Ana Luísa Cunha, Jéssica Rodrigues, Luís Antunes, Rui Henrique, Carmen Jerónimo
Published 2019-09-01

Cell-Free DNA Methylation of Selected Genes Allows for Early Detection of the Major Cancers in Women

by Sandra P. Nunes, Catarina Moreira-Barbosa, Sofia Salta, Susana Palma de Sousa, Inês Pousa, Júlio Oliveira, Marta Soares, Licínio Rego, Teresa Dias, Jéssica Rodrigues, Luís Antunes, Rui Henrique, Carmen Jerónimo
Published 2018-09-01

Altered expression of MGMT in high-grade gliomas results from the combined effect of epigenetic and genetic aberrations.

by João Ramalho-Carvalho, Malini Pires, Susana Lisboa, Inês Graça, Patrícia Rocha, João Diogo Barros-Silva, Joana Savva-Bordalo, Joaquina Maurício, Mário Resende, Manuel R Teixeira, Mrinalini Honavar, Rui Henrique, Carmen Jerónimo
Published 2013-01-01

FOXA1 levels are decreased in pleural breast cancer metastases after adjuvant endocrine therapy, and this is associated with poor outcome

by Willemijne Schrijver, Karianne Schuurman, Annelot vanRossum, Marjolein Droog, Carmen Jeronimo, Sofia Salta, Rui Henrique, Jelle Wesseling, Cathy Moelans, Sabine C. Linn, Michel van denHeuvel, Paul vanDiest, Wilbert Zwart
Published 2018-11-01

Cysteine-rich secretory protein-3 (CRISP3) is strongly up-regulated in prostate carcinomas with the TMPRSS2-ERG fusion gene.

by Franclim R Ribeiro, Paula Paulo, Vera L Costa, João D Barros-Silva, João Ramalho-Carvalho, Carmen Jerónimo, Rui Henrique, Guro E Lind, Rolf I Skotheim, Ragnhild A Lothe, Manuel R Teixeira
Published 2011-01-01

<i>XIST</i>-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

by João Lobo, Sandra P. Nunes, Ad J. M. Gillis, Daniela Barros-Silva, Vera Miranda-Gonçalves, Annette van den Berg, Mariana Cantante, Rita Guimarães, Rui Henrique, Carmen Jerónimo, Leendert H. J. Looijenga
Published 2019-09-01

Overexpression of circulating MiR-30b-5p identifies advanced breast cancer

by Helena Estevão-Pereira, João Lobo, Sofia Salta, Maria Amorim, Paula Lopes, Mariana Cantante, Berta Reis, Luís Antunes, Fernando Castro, Susana Palma de Sousa, Céline S. Gonçalves, Bruno M. Costa, Rui Henrique, Carmen Jerónimo
Published 2019-12-01

Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.

by Maria J Camões, Paula Paulo, Franclim R Ribeiro, João D Barros-Silva, Mafalda Almeida, Vera L Costa, Nuno Cerveira, Rolf I Skotheim, Ragnhild A Lothe, Rui Henrique, Carmen Jerónimo, Manuel R Teixeira
Published 2012-01-01

Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype

by Tânia Soraia Vieira-Silva, Sara Monteiro-Reis, Daniela Barros-Silva, João Ramalho-Carvalho, Inês Graça, Isa Carneiro, Ana Teresa Martins, Jorge Oliveira, Luis Antunes, Sarah Hurtado-Bagès, Marcus Buschbeck, Rui Henrique, Carmen Jerónimo
Published 2019-04-01

The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors

by Vera Miranda-Gonçalves, João Lobo, Catarina Guimarães-Teixeira, Daniela Barros-Silva, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique, Carmen Jerónimo
Published 2021-08-01

Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors

by João Lobo, Catarina Guimarães-Teixeira, Daniela Barros-Silva, Vera Miranda-Gonçalves, Vânia Camilo, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert HJ Looijenga, Rui Henrique, Carmen Jerónimo
Published 2020-10-01

Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer

by Iris Garrido-Cano, Vera Constâncio, Anna Adam-Artigues, Ana Lameirinhas, Soraya Simón, Belen Ortega, María Teresa Martínez, Cristina Hernando, Begoña Bermejo, Ana Lluch, Paula Lopes, Rui Henrique, Carmen Jerónimo, Juan Miguel Cejalvo, Pilar Eroles
Published 2020-10-01

Clinical Significance of ARID1A and ANXA1 in HER-2 Positive Breast Cancer

by Rita Silva-Oliveira, Filipa Ferreira Pereira, Sara Petronilho, Ana Teresa Martins, Ana Lameirinhas, Vera Constâncio, Inês Caldas-Ribeiro, Sofia Salta, Paula Lopes, Luís Antunes, Fernando Castro, Susana Palma de Sousa, Rui Henrique, Carmen Jerónimo
Published 2020-12-01

Promoter methylation of DNA homologous recombination genes is predictive of the responsiveness to PARP inhibitor treatment in testicular germ cell tumors

by João Lobo, Vera Constâncio, Catarina Guimarães‐Teixeira, Pedro Leite‐Silva, Vera Miranda‐Gonçalves, José Pedro Sequeira, Laura Pistoni, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Leendert H. J. Looijenga, Rui Henrique, Carmen Jerónimo
Published 2021-04-01

Molecular Subtyping of Primary Prostate Cancer Reveals Specific and Shared Target Genes of Different ETS Rearrangements

by Paula Paulo, Franclim R. Ribeiro, Joana Santos, Diana Mesquita, Mafalda Almeida, João D. Barros-Silva, Harri Itkonen, Rui Henrique, Carmen Jerónimo, Anita Sveen, Ian G. Mills, Rolf I. Skotheim, Ragnhild A. Lothe, Manuel R. Teixeira
Published 2012-07-01

Integrative epigenetic taxonomy of primary prostate cancer

by Suzan Stelloo, Ekaterina Nevedomskaya, Yongsoo Kim, Karianne Schuurman, Eider Valle-Encinas, João Lobo, Oscar Krijgsman, Daniel Simon Peeper, Seiwon Laura Chang, Felix Yi-Chung Feng, Lodewyk Frederik Ary Wessels, Rui Henrique, Carmen Jerónimo, Andries Marinus Bergman, Wilbert Zwart
Published 2018-11-01

Identification of a Two-MicroRNA Signature in Plasma as a Novel Biomarker for Very Early Diagnosis of Breast Cancer

by Anna Adam-Artigues, Iris Garrido-Cano, Juan Antonio Carbonell-Asins, Ana Lameirinhas, Soraya Simón, Belén Ortega-Morillo, María Teresa Martínez, Cristina Hernando, Vera Constâncio, Octavio Burgues, Begoña Bermejo, Rui Henrique, Ana Lluch, Carmen Jerónimo, Pilar Eroles, Juan Miguel Cejalvo
Published 2021-06-01

Assessment of HER2 Protein Overexpression and Gene Amplification in Renal Collecting Duct Carcinoma: Therapeutic Implication

by Manuela Costantini, Carla Azzurra Amoreo, Liborio Torregrossa, Greta Alì, Enrico Munari, Carmen Jeronimo, Rui Henrique, Sara Petronilho, Umberto Capitanio, Roberta Lucianò, Nazareno Suardi, Maria Teresa Landi, Umberto Anceschi, Aldo Brassetti, Vito Michele Fazio, Michele Gallucci, Giuseppe Simone, Steno Sentinelli, Maria Luana Poeta
Published 2020-11-01

Circulating extracellular vesicles release oncogenic miR-424 in experimental models and patients with aggressive prostate cancer

by Domenico Albino, Martina Falcione, Valeria Uboldi, Dada Oluwaseyi Temilola, Giada Sandrini, Jessica Merulla, Gianluca Civenni, Aleksandra Kokanovic, Alessandra Stürchler, Dheeraj Shinde, Mariangela Garofalo, Ricardo Pereira Mestre, Vera Constâncio, Martha Wium, Jacopo Burrello, Nicolò Baranzini, Annalisa Grimaldi, Jean-Philippe Theurillat, Daniela Bossi, Lucio Barile, Rui M. Henrique, Carmen Jeronimo, Luiz Fernando Zerbini, Carlo V. Catapano, Giuseppina M. Carbone
Published 2021-01-01

Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancerResearch in context

by Patrice Hodonou Avogbe, Arnaud Manel, Emmanuel Vian, Geoffroy Durand, Nathalie Forey, Catherine Voegele, Maria Zvereva, Md Ismail Hosen, Sonia Meziani, Berengere De Tilly, Gilles Polo, Olesia Lole, Pauline Francois, Tiffany Myriam Delhomme, Christine Carreira, Sara Monteiro-Reis, Rui Henrique, Behnoush Abedi-Ardekani, Graham Byrnes, Matthieu Foll, Elisabete Weiderpass, James McKay, Carmen Jeronimo, Ghislaine Scelo, Florence Le Calvez-Kelm
Published 2019-06-01