Validation of a scale for assessing attitudes towards outcomes of genetic cancer testing among primary care providers and breast specialists.

by Anne-Deborah Bouhnik, Khadim N'Diaye, D Gareth Evans, Hilary Harris, Aad Tibben, Christi van Asperen, Joerg Schmidtke, Irmgard Nippert, Julien Mancini, Claire Julian-Reynier
Published 2017-01-01

Mammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years

by Adam R. Brentnall, Ruth Warren, Elaine F. Harkness, Susan M. Astley, Julia Wiseman, Jill Fox, Lynne Fox, Mikael Eriksson, Per Hall, Jack Cuzick, D. Gareth Evans, Anthony Howell
Published 2020-09-01

Improvement in risk prediction, early detection and prevention of breast cancer in the NHS Breast Screening Programme and family history clinics: a dual cohort study

by D Gareth Evans, Susan Astley, Paula Stavrinos, Elaine Harkness, Louise S Donnelly, Sarah Dawe, Ian Jacob, Michelle Harvie, Jack Cuzick, Adam Brentnall, Mary Wilson, Fiona Harrison, Katherine Payne, Anthony Howell
Published 2016-08-01

Histological and Somatic Mutational Profiles of Mismatch Repair Deficient Endometrial Tumours of Different Aetiologies

by Neil A. J. Ryan, Thomas D. J. Walker, James Bolton, Natalja ter Haar, Tom Van Wezel, Mark A. Glaire, David N. Church, D. Gareth Evans, Tjalling Bosse, Emma J. Crosbie
Published 2021-09-01

Fanconi anemia with sun-sensitivity caused by a Xeroderma pigmentosum-associated missense mutation in XPF

by Isabell Popp, Maqsood Punekar, Nick Telford, Stavros Stivaros, Kate Chandler, Meenakshi Minnis, Anna Castleton, Claire Higham, Louise Hopewell, D. Gareth Evans, Anja Raams, Arjan F. Theil, Stefan Meyer, Detlev Schindler
Published 2018-01-01

Uptake of bilateral-risk-reducing-mastectomy: Prospective analysis of 7195 women at high-risk of breast cancer

by D.Gareth Evans, Ashu Gandhi, Julie Wisely, Tara Clancy, Emma R. Woodward, James Harvey, Lyndsey Highton, John Murphy, Lester Barr, Sacha J. Howell, Fiona Lalloo, Elaine F. Harkness, Anthony Howell
Published 2021-12-01

Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in <i>BRCA1, BRCA2</i>, and <i>TP53</i> Genes in Women with Very Early-Onset (&lt;36 Years) Breast...

by Zerin Hyder, Elaine F. Harkness, Emma R. Woodward, Naomi L. Bowers, Marta Pereira, Andrew J. Wallace, Sacha J. Howell, Anthony Howell, Fiona Lalloo, William G. Newman, Miriam J. Smith, D Gareth Evans
Published 2020-02-01

Preferences for breast cancer prevention among women with a BRCA1 or BRCA2 mutation

by Carol A. Mansfield, Kelly A. Metcalfe, Carrie Snyder, Geoffrey J. Lindeman, Joshua Posner, Sue Friedman, Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer, Henry T. Lynch, Steven A. Narod, D. Gareth Evans, Alexander Liede
Published 2020-09-01

Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics: the Cohort study of TP53 carrier early onset breast cancer (COPE study)

by Kate Packwood, Guy Martland, Matthew Sommerlad, Emily Shaw, Karwan Moutasim, Gareth Thomas, Adrian C Bateman, Louise Jones, Linda Haywood, D Gareth Evans, Jillian M Birch, Ohud A Alsalmi, Alex Henderson, Nicola Poplawski, Diana M Eccles
Published 2019-07-01

Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior <i>BRCA1/2</i> Probability

by D. Gareth Evans, Elke M. van Veen, Emma R. Woodward, Elaine F. Harkness, Jamie M. Ellingford, Naomi L. Bowers, Andrew J. Wallace, Sacha J. Howell, Anthony Howell, Fiona Lalloo, William G. Newman, Miriam J. Smith
Published 2021-08-01

The Angelina Jolie effect: Contralateral risk-reducing mastectomy trends in patients at increased risk of breast cancer

by Narendra Nath Basu, James Hodson, Shaunak Chatterjee, Ashu Gandhi, Julie Wisely, James Harvey, Lyndsey Highton, John Murphy, Nicola Barnes, Richard Johnson, Lester Barr, Cliona C. Kirwan, Sacha Howell, Andrew D. Baildam, Anthony Howell, D. Gareth Evans
Published 2021-02-01

Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers

by Martin Widschwendter, Matthew Burnell, Lindsay Fraser, Adam N. Rosenthal, Sue Philpott, Daniel Reisel, Louis Dubeau, Mark Cline, Yang Pan, Ping-Cheng Yi, D. Gareth Evans, Ian J. Jacobs, Usha Menon, Charles E. Wood, William C. Dougall
Published 2015-10-01

Breast cancer risk in a screening cohort of Asian and white British/Irish women from Manchester UK

by D. Gareth Evans, Adam R. Brentnall, Michelle Harvie, Susan Astley, Elaine F. Harkness, Paula Stavrinos, Louise S. Donnelly, Sarah Sampson, Faiza Idries, Donna Watterson, Jack Cuzick, Mary Wilson, Anil Jain, Fiona Harrison, Anthony J. Maxwell, Anthony Howell
Published 2018-01-01

A comparison of five methods of measuring mammographic density: a case-control study

by Susan M. Astley, Elaine F. Harkness, Jamie C. Sergeant, Jane Warwick, Paula Stavrinos, Ruth Warren, Mary Wilson, Ursula Beetles, Soujanya Gadde, Yit Lim, Anil Jain, Sara Bundred, Nicola Barr, Valerie Reece, Adam R. Brentnall, Jack Cuzick, Tony Howell, D. Gareth Evans
Published 2018-02-01

Long-Term Evaluation of Women Referred to a Breast Cancer Family History Clinic (Manchester UK 1987–2020)

by Anthony Howell, Ashu Gandhi, Sacha Howell, Mary Wilson, Anthony Maxwell, Susan Astley, Michelle Harvie, Mary Pegington, Lester Barr, Andrew Baildam, Elaine Harkness, Penelope Hopwood, Julie Wisely, Andrea Wilding, Rosemary Greenhalgh, Jenny Affen, Andrew Maurice, Sally Cole, Julia Wiseman, Fiona Lalloo, David P. French, D. Gareth Evans
Published 2020-12-01

The proportion of endometrial tumours associated with Lynch syndrome (PETALS): A prospective cross-sectional study.

by Neil A J Ryan, Raymond McMahon, Simon Tobi, Tristan Snowsill, Shona Esquibel, Andrew J Wallace, Sancha Bunstone, Naomi Bowers, Ioana E Mosneag, Sarah J Kitson, Helena O'Flynn, Neal C Ramchander, Vanitha N Sivalingam, Ian M Frayling, James Bolton, Rhona J McVey, D Gareth Evans, Emma J Crosbie
Published 2020-09-01

Randomised controlled trial of simvastatin treatment for autism in young children with neurofibromatosis type 1 (SANTA)

by Stavros Stivaros, Shruti Garg, Maria Tziraki, Ying Cai, Owen Thomas, Joseph Mellor, Andrew A. Morris, Carly Jim, Karolina Szumanska-Ryt, Laura M Parkes, Hamied A. Haroon, Daniela Montaldi, Nicholas Webb, John Keane, Francisco X. Castellanos, Alcino J. Silva, Sue Huson, Stephen Williams, D. Gareth Evans, Richard Emsley, Jonathan Green, SANTA Consortium
Published 2018-02-01

Author Correction: Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

by Nicola Whiffin, Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans, Angharad M. Roberts, Nicholas M. Quaife, Sebastian Schafer, Owen Rackham, Jessica Alföldi, Anne H. O’Donnell-Luria, Laurent C. Francioli, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Stuart A. Cook, Paul J. R. Barton, Daniel G. MacArthur, James S. Ware
Published 2021-02-01

What are the benefits and harms of risk stratified screening as part of the NHS breast screening Programme? Study protocol for a multi-site non-randomised comparison of BC-predict...

by David P. French, Susan Astley, Adam R. Brentnall, Jack Cuzick, Richard Dobrashian, Stephen W. Duffy, Louise S. Gorman, Elaine F. Harkness, Fiona Harrison, Michelle Harvie, Anthony Howell, Andrew Jerrison, Matthew Machin, Anthony J. Maxwell, Lorna McWilliams, Katherine Payne, Nadeem Qureshi, Helen Ruane, Sarah Sampson, Paula Stavrinos, Emma Thorpe, Fiona Ulph, Tjeerd van Staa, Victoria Woof, D. Gareth Evans
Published 2020-06-01

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

by Nicola Whiffin, Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans, Angharad M. Roberts, Nicholas M. Quaife, Sebastian Schafer, Owen Rackham, Jessica Alföldi, Anne H. O’Donnell-Luria, Laurent C. Francioli, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Stuart A. Cook, Paul J. R. Barton, Daniel G. MacArthur, James S. Ware
Published 2020-05-01