Applications of Dynamic Clamp to Cardiac Arrhythmia Research: Role in Drug Target Discovery and Safety Pharmacology Testing

by Francis A. Ortega, Eleonora Grandi, Trine Krogh-Madsen, David J. Christini, David J. Christini
Published 2018-01-01

Cell-specific cardiac electrophysiology models.

by Willemijn Groenendaal, Francis A Ortega, Armen R Kherlopian, Andrew C Zygmunt, Trine Krogh-Madsen, David J Christini
Published 2015-04-01

Overexpression of Map3k7 activates sinoatrial node-like differentiation in mouse ES-derived cardiomyocytes.

by Kemar Brown, Stephanie Legros, Francis A Ortega, Yunkai Dai, Michael Xavier Doss, David J Christini, Richard B Robinson, Ann C Foley
Published 2017-01-01

Global Optimization of Ventricular Myocyte Model to Multi-Variable Objective Improves Predictions of Drug-Induced Torsades de Pointes

by Trine Krogh-Madsen, Trine Krogh-Madsen, Trine Krogh-Madsen, Anna F. Jacobson, Francis A. Ortega, David J. Christini, David J. Christini, David J. Christini
Published 2017-12-01

Rapid genetic algorithm optimization of a mouse computational model: Benefits for anthropomorphization of neonatal mouse cardiomyocytes

by Corina Teodora Bot, Armen R. Kherlopian, Armen R. Kherlopian, Francis A. Ortega, David J. Christini, David J. Christini, Trine eKrogh-Madsen, Trine eKrogh-Madsen, Trine eKrogh-Madsen
Published 2012-11-01