HCN Channels: New Therapeutic Targets for Pain Treatment

by David Ramírez, Rafael Zúñiga, Guierdy Concha, Leandro Zúñiga
Published 2018-08-01

TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines

by Rafael Zúñiga, Claudio Valenzuela, Guierdy Concha, Nelson Brown, Leandro Zúñiga
Published 2018-03-01

The Insensitivity of TASK-3 K2P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure

by Guierdy Concha, Daniel Bustos, Rafael Zúñiga, Marcelo A. Catalán, Leandro Zúñiga
Published 2018-08-01

Correction: Concha, G., et al. The Insensitivity of TASK-3 K₂P Channels to External Tetraethylammonium (TEA) Partially Depends on the Cap Structure. <i>Int. J. Mol. Sci....

by Guierdy Concha, Daniel Bustos, Rafael Zúñiga, Marcelo A. Catalán, Leandro Zúñiga
Published 2019-09-01

Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3

by Rafael Zúñiga, Guierdy Concha, Angel Cayo, Rocio Cikutović-Molina, Bárbara Arevalo, Wendy González, Marcelo A. Catalán, Leandro Zúñiga
Published 2020-09-01

Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K₂P Channels

by Daniel Bustos, Mauricio Bedoya, David Ramírez, Guierdy Concha, Leandro Zúñiga, Niels Decher, Erix W. Hernández-Rodríguez, Francisco V. Sepúlveda, Leandro Martínez, Wendy González
Published 2020-01-01

Discovery of Novel TASK-3 Channel Blockers Using a Pharmacophore-Based Virtual Screening

by David Ramírez, Guierdy Concha, Bárbara Arévalo, Luis Prent-Peñaloza, Leandro Zúñiga, Aytug K. Kiper, Susanne Rinné, Miguel Reyes-Parada, Niels Decher, Wendy González, Julio Caballero
Published 2019-08-01