Dynamic interaction between fetal adversity and a genetic score reflecting dopamine function on developmental outcomes at 36 months.

by Adrianne R Bischoff, Irina Pokhvisneva, Étienne Léger, Hélène Gaudreau, Meir Steiner, James L Kennedy, Kieran J O'Donnell, Josie Diorio, Michael J Meaney, Patrícia P Silveira, MAVAN research team
Published 2017-01-01

Early Life Adversity and Polygenic Risk for High Fasting Insulin Are Associated With Childhood Impulsivity

by Aashita Batra, Aashita Batra, Lawrence M. Chen, Lawrence M. Chen, Zihan Wang, Carine Parent, Irina Pokhvisneva, Sachin Patel, Robert D. Levitan, Michael J. Meaney, Michael J. Meaney, Michael J. Meaney, Patricia Pelufo Silveira, Patricia Pelufo Silveira
Published 2021-09-01

A biologically-informed polygenic score identifies endophenotypes and clinical conditions associated with the insulin receptor function on specific brain regionsResearch in context

by Shantala A. Hari Dass, Kathryn McCracken, Irina Pokhvisneva, Lawrence M. Chen, Elika Garg, Thao T.T. Nguyen, Zihan Wang, Barbara Barth, Moein Yaqubi, Lisa M. McEwen, Julie L. MacIsaac, Josie Diorio, Michael S. Kobor, Kieran J. O'Donnell, Michael J. Meaney, Patricia P. Silveira
Published 2019-04-01

PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores

by Lawrence M. Chen, Nelson Yao, Elika Garg, Yuecai Zhu, Thao T. T. Nguyen, Irina Pokhvisneva, Shantala A. Hari Dass, Eva Unternaehrer, Hélène Gaudreau, Marie Forest, Lisa M. McEwen, Julia L. MacIsaac, Michael S. Kobor, Celia M. T. Greenwood, Patricia P. Silveira, Michael J. Meaney, Kieran J. O’Donnell
Published 2018-08-01

Amygdala 5-HTT Gene Network Moderates the Effects of Postnatal Adversity on Attention Problems: Anatomo-Functional Correlation and Epigenetic Changes

by Randriely Merscher Sobreira de Lima, Barbara Barth, Danusa Mar Arcego, Euclides José de Mendonça Filho, Euclides José de Mendonça Filho, Andrew Clappison, Sachin Patel, Zihan Wang, Irina Pokhvisneva, Roberto Britto Sassi, Geoffrey B. C. Hall, Michael S. Kobor, Kieran J. O'Donnell, Kieran J. O'Donnell, Kieran J. O'Donnell, Ana Paula Santana de Vasconcellos Bittencourt, Michael J. Meaney, Michael J. Meaney, Michael J. Meaney, Michael J. Meaney, Carla Dalmaz, Patrícia Pelufo Silveira, Patrícia Pelufo Silveira, Patrícia Pelufo Silveira
Published 2020-03-01