SUMO conjugation to the pattern recognition receptor FLS2 triggers intracellular signalling in plant innate immunity

by Beatriz Orosa, Gary Yates, Vivek Verma, Anjil K. Srivastava, Moumita Srivastava, Alberto Campanaro, Daniel De Vega, Alanna Fernandes, Cunjin Zhang, Jack Lee, Malcolm J. Bennett, Ari Sadanandom
Published 2018-12-01

Tolerability and Efficacy of Customized IncobotulinumtoxinA Injections for Essential Tremor: A Randomized, Double-blind, Placebo-Controlled Study

by Mandar Jog, Jack Lee, Astrid Scheschonka, Robert Chen, Farooq Ismail, Chris Boulias, Douglas Hobson, David King, Michael Althaus, Olivier Simon, Hanna Dersch, Steven Frucht, David M. Simpson
Published 2020-12-01

Immuno-profiling and cellular spatial analysis using five immune oncology multiplex immunofluorescence panels for paraffin tumor tissue

by Edwin Roger Parra, Maria C. Ferrufino-Schmidt, Auriole Tamegnon, Jiexin Zhang, Luisa Solis, Mei Jiang, Heladio Ibarguen, Cara Haymaker, J. Jack Lee, Chantale Bernatchez, Ignacio Ivan Wistuba
Published 2021-04-01

Enhancing coronary Wave Intensity Analysis robustness by high order central finite differences

by Simone Rivolo, Kaleab N. Asrress, Amedeo Chiribiri, Eva Sammut, Roman Wesolowski, Lars Ø. Bloch, Anne K. Grøndal, Jesper L. Hønge, Won Y. Kim, Michael Marber, Simon Redwood, Eike Nagel, Nicolas P. Smith, Jack Lee
Published 2014-04-01

Coagulation derangement and risk factors for valve thrombosis following transcatheter aortic valve implantation

by Ronak Rajani, Kiran Parmar, Bernard D Prendergast, Christopher Allen, Tiffany Patterson, Simon R Redwood, Beverley Hunt, Julia Grapsa, Jack Lee, Christopher Young, Harriet Hurrell, Rebecca Preston, Gianluca Lucchese, Giulia Esposito, Utkarsh Dutta, Nicholas Aroney, Fiyyaz Ahmed-Jushuf
Published 2021-06-01

Assessing PIK3CA and PTEN in Early-Phase Trials with PI3K/AKT/mTOR Inhibitors

by Filip Janku, David S. Hong, Siqing Fu, Sarina A. Piha-Paul, Aung Naing, Gerald S. Falchook, Apostolia M. Tsimberidou, Vanda M. Stepanek, Stacy L. Moulder, J. Jack Lee, Rajyalakshmi Luthra, Ralph G. Zinner, Russell R. Broaddus, Jennifer J. Wheler, Razelle Kurzrock
Published 2014-01-01

The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells

by Hye-Jin Boo, Hye-Young Min, Hyun-Ji Jang, Hye Jeong Yun, John Kendal Smith, Quanri Jin, Hyo-Jong Lee, Diane Liu, Hee-Seok Kweon, Carmen Behrens, J. Jack Lee, Ignacio I. Wistuba, Euni Lee, Waun Ki Hong, Ho-Young Lee
Published 2016-09-01

Impact of coronary artery disease on contractile function and ventricular‐arterial coupling during exercise: Simultaneous assessment of left‐ventricular pressure–volume and coronar...

by Tiffany Patterson, Simone Rivolo, Daniel Burkhoff, Jan Schreuder, Natalia Briceno, Rupert Williams, Satpal Arri, Kaleab N. Asrress, Christopher Allen, Jubin Joseph, Hannah Z. R. McConkey, Howard Ellis, Antonis Pavlidis, Brian Clapp, Divaka Perera, Jack Lee, Michael S. Marber, Simon R. Redwood
Published 2021-05-01

Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.

by Charles Lu, David J Stewart, J Jack Lee, Lin Ji, Rajagopal Ramesh, Gitanjali Jayachandran, Maria I Nunez, Ignacio I Wistuba, Jeremy J Erasmus, Marshall E Hicks, Elizabeth A Grimm, James M Reuben, Veerabhadran Baladandayuthapani, Nancy S Templeton, John D McMannis, Jack A Roth
Published 2012-01-01

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.

by Yun-Ju Chen, Wei-Chien Huang, Ya-Ling Wei, Sheng-Chieh Hsu, Ping Yuan, Heather Y Lin, Ignacio I Wistuba, J Jack Lee, Chia-Jui Yen, Wu-Chou Su, Kwang-Yu Chang, Wen-Chang Chang, Tse-Chuan Chou, Chao-Kai Chou, Chang-Hai Tsai, Mien-Chie Hung
Published 2011-01-01

Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study

by Jason K. Sicklick, Shumei Kato, Ryosuke Okamura, Hitendra Patel, Mina Nikanjam, Paul T. Fanta, Michael E. Hahn, Pradip De, Casey Williams, Jessica Guido, Benjamin M. Solomon, Rana R. McKay, Amy Krie, Sarah G. Boles, Jeffrey S. Ross, J. Jack Lee, Brian Leyland-Jones, Scott M. Lippman, Razelle Kurzrock
Published 2021-10-01

Effect of neoadjuvant chemotherapy on the immune microenvironment in non–small cell lung carcinomas as determined by multiplex immunofluorescence and image analysis approaches

by Edwin R. Parra, Pamela Villalobos, Carmen Behrens, Mei Jiang, Apar Pataer, Stephen G. Swisher, William N. William, Jiexin Zhang, Jack Lee, Tina Cascone, John V. Heymach, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Neda Kalhor, Annikka Weissferdt, Cesar Moran, Jianjun Zhang, Ara Vaporciyan, Don L. Gibbons, Boris Sepesi, Ignacio I. Wistuba
Published 2018-06-01

Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity

by Kathleen M. McAndrews, Dara P. Dowlatshahi, Jianli Dai, Lisa M. Becker, Janine Hensel, Laura M. Snowden, Jennifer M. Leveille, Michael R. Brunner, Kylie W. Holden, Nikolas S. Hopkins, Alexandria M. Harris, Jerusha Kumpati, Michael A. Whitt, J. Jack Lee, Luis L. Ostrosky-Zeichner, Ramesha Papanna, Valerie S. LeBleu, James P. Allison, Raghu Kalluri
Published 2020-09-01

809 Phase 2 trial of neoadjuvant and adjuvant PD-1 checkpoint blockade in local-regionally advanced, resectable HNSCC indicates pathological response is associated with high diseas...

by Trisha Wise-Draper, Diana Bell, Roman Jandarov, Shuchi Gulati, Maura Gillison, Vinita Takiar, Sarah Palackdharry, Francis Worden, Matthew Old, John Kaczmar, Neal Dunlap, Benjamin Hinrichs, Yash Patil, Muhammad Kashif Riaz, Layne Weatherford, Aubrey Hamilton, Sheena Lanverman, Michelle Mierzwa, Keith Casper, Jonathan Mark, Alice Tang, Chad Zender, Ann Gillenwater, Mario Medvedovich, J Jack Lee
Published 2020-11-01

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

by Jingying Nong, Yuhua Gong, Yanfang Guan, Xin Yi, Yuting Yi, Lianpeng Chang, Ling Yang, Jialin Lv, Zhirong Guo, Hongyan Jia, Yuxing Chu, Tao Liu, Ming Chen, Lauren Byers, Emily Roarty, Vincent K. Lam, Vassiliki A. Papadimitrakopoulou, Ignacio Wistuba, John V. Heymach, Bonnie Glisson, Zhongxing Liao, J. Jack Lee, P. Andrew Futreal, Shucai Zhang, Xuefeng Xia, Jianjun Zhang, Jinghui Wang
Published 2018-08-01

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

by Jingying Nong, Yuhua Gong, Yanfang Guan, Xin Yi, Yuting Yi, Lianpeng Chang, Ling Yang, Jialin Lv, Zhirong Guo, Hongyan Jia, Yuxing Chu, Tao Liu, Ming Chen, Lauren Byers, Emily Roarty, Vincent K. Lam, Vassiliki A. Papadimitrakopoulou, Ignacio Wistuba, John V. Heymach, Bonnie Glisson, Zhongxing Liao, J. Jack Lee, P. Andrew Futreal, Shucai Zhang, Xuefeng Xia, Jianjun Zhang, Jinghui Wang
Published 2019-01-01

The physiological effects of cardiac resynchronization therapy on aortic and pulmonary flow and dynamic and static components of systemic impedance

by Baldeep S. Sidhu, PhD, Simon Claridge, PhD, Haotian Gu, PhD, Ye Li, PhD), Justin Gould, PhD, Bradley Porter, PhD, Mark K. Elliott, MBBS, Vishal Mehta, MBBS, Tom Jackson, PhD, Tiffany Patterson, PhD, Natalia Briceno, MBBS, Jack Lee, DPhil, Simon Redwood, MD, Shaumik Adhya, FHRS, Steven A. Niederer, DPhil, Phil Chowienczyk, BSc, Christopher A. Rinaldi, FHRS
Published 2021-08-01

Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer

by Jeri Kim, John W. Davis, Eric A. Klein, Cristina Magi-Galluzzi, Yair Lotan, John F. Ward, Louis L. Pisters, Joseph W. Basler, Curtis A. Pettaway, Andrew Stephenson, Elsa M. Li Ning Tapia, Eleni Efstathiou, Xuemei Wang, Kim-Anh Do, J. Jack Lee, Ivan P. Gorlov, Lana A. Vornik, Ashraful M. Hoque, Ina N. Prokhorova, Howard L. Parnes, Scott M. Lippman, Ian M. Thompson, Powel H. Brown, Christopher J. Logothetis, Patricia Troncoso
Published 2016-05-01

Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas

by Xin Hu, Marcos R. Estecio, Runzhe Chen, Alexandre Reuben, Linghua Wang, Junya Fujimoto, Jian Carrot-Zhang, Nicholas McGranahan, Lisha Ying, Junya Fukuoka, Chi-Wan Chow, Hoa H. N. Pham, Myrna C. B. Godoy, Brett W. Carter, Carmen Behrens, Jianhua Zhang, Mara B. Antonoff, Boris Sepesi, Yue Lu, Harvey I. Pass, Humam Kadara, Paul Scheet, Ara A. Vaporciyan, John V. Heymach, Ignacio I. Wistuba, J. Jack Lee, P. Andrew Futreal, Dan Su, Jean-Pierre J. Issa, Jianjun Zhang
Published 2021-01-01

Nodal immune flare mimics nodal disease progression following neoadjuvant immune checkpoint inhibitors in non-small cell lung cancer

by Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Published 2021-08-01