Chimeric antigen receptorâengineered T cells as oncolytic virus carriers

by Heather VanSeggelen, Daniela GM Tantalo, Arya Afsahi, Joanne A Hammill, Jonathan L Bramson
Published 2015-01-01

Alterations to the frequency and function of peripheral blood monocytes and associations with chronic disease in the advanced-age, frail elderly.

by Chris P Verschoor, Jennie Johnstone, Jamie Millar, Robin Parsons, Alina Lelic, Mark Loeb, Jonathan L Bramson, Dawn M E Bowdish
Published 2014-01-01

HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants

by Andrew Nguyen, Louisa Ho, Samuel T. Workenhe, Lan Chen, Jonathan Samson, Scott R. Walsh, Jonathan Pol, Jonathan L. Bramson, Yonghong Wan
Published 2018-07-01

The polyfunctionality of human memory CD8+ T cells elicited by acute and chronic virus infections is not influenced by age.

by Alina Lelic, Chris P Verschoor, Mario Ventresca, Robin Parsons, Carole Evelegh, Dawn Bowdish, Michael R Betts, Mark B Loeb, Jonathan L Bramson
Published 2012-01-01

Surface phenotype and functionality of WNV specific T cells differ with age and disease severity.

by Paolo Piazza, Curtis P McMurtrey, Alina Lelic, Robert L Cook, Rachel Hess, Eric Yablonsky, Luann Borowski, Mark B Loeb, Jonathan L Bramson, William H Hildebrand, Charles R Rinaldo
Published 2010-12-01

A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity

by Joanne A. Hammill, Jacek M. Kwiecien, Anna Dvorkin-Gheva, Vivian W.C. Lau, Christopher Baker, Ying Wu, Ksenia Bezverbnaya, Craig Aarts, Christopher W. Heslen, Galina F. Denisova, Heather Derocher, Katy Milne, Brad H. Nelson, Jonathan L. Bramson
Published 2020-06-01

Correction: Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence.

by Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Published 2016-01-01

Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence.

by Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Published 2016-01-01

Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors

by Ana L. Portillo, Richard Hogg, Sophie M. Poznanski, Eduardo A. Rojas, Niamh J. Cashell, Joanne A. Hammill, Marianne V. Chew, Mira M. Shenouda, Tyrah M. Ritchie, Quynh T. Cao, Jeremy A. Hirota, Sukhbinder Dhesy-Thind, Jonathan L. Bramson, Ali A. Ashkar
Published 2021-06-01

The chimeric TAC receptor co-opts the T cell receptor yielding robust anti-tumor activity without toxicity

by Christopher W. Helsen, Joanne A. Hammill, Vivian W. C. Lau, Kenneth A. Mwawasi, Arya Afsahi, Ksenia Bezverbnaya, Lisa Newhook, Danielle L. Hayes, Craig Aarts, Bojana Bojovic, Galina F. Denisova, Jacek M. Kwiecien, Ian Brain, Heather Derocher, Katy Milne, Brad H. Nelson, Jonathan L. Bramson
Published 2018-08-01

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

by Jonathan G. Pol, Sergio A. Acuna, Beta Yadollahi, Nan Tang, Kyle B. Stephenson, Matthew J. Atherton, David Hanwell, Alexander El-Warrak, Alyssa Goldstein, Badru Moloo, Patricia V. Turner, Roberto Lopez, Sandra LaFrance, Carole Evelegh, Galina Denisova, Robin Parsons, Jamie Millar, Gautier Stoll, Chantal G. Martin, Julia Pomoransky, Caroline J. Breitbach, Jonathan L. Bramson, John C. Bell, Yonghong Wan, David F. Stojdl, Brian D. Lichty, J. Andrea McCart
Published 2019-01-01