Noncoding Subgenomic Flavivirus RNA: Multiple Functions in West Nile Virus Pathogenesis and Modulation of Host Responses

by Justin A. Roby, Gorben P. Pijlman, Jeffrey Wilusz, Alexander A. Khromykh
Published 2014-01-01

The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

by Sofiya Tsimbalyuk, Emily M. Cross, Mikayla Hoad, Camilla M. Donnelly, Justin A. Roby, Jade K. Forwood
Published 2020-08-01

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.

by Matthew A Burchill, Justin A Roby, Nanette Crochet, Megan Wind-Rotolo, Amy E Stone, Michael G Edwards, Rachael J Dran, Michael S Kriss, Michael Gale, Hugo R Rosen
Published 2017-01-01

Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling

by Justin A. Roby, Katharina Esser-Nobis, Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Johannes Schwerk, Amy Y. Lu, Frank W. Soveg, Emily A. Hemann, Lauren D. Hatfield, Brian C. Keller, Alexander Shapiro, Adriana Forero, Jennifer E. Stencel-Baerenwald, Ram Savan, Michael Gale
Published 2020-04-01

Endomembrane targeting of human OAS1 p46 augments antiviral activity

by Frank W Soveg, Johannes Schwerk, Nandan S Gokhale, Karen Cerosaletti, Julian R Smith, Erola Pairo-Castineira, Alison M Kell, Adriana Forero, Shivam A Zaver, Katharina Esser-Nobis, Justin A Roby, Tien-Ying Hsiang, Snehal Ozarkar, Jonathan M Clingan, Eileen T McAnarney, Amy EL Stone, Uma Malhotra, Cate Speake, Joseph Perez, Chiraag Balu, Eric J Allenspach, Jennifer L Hyde, Vineet D Menachery, Saumendra N Sarkar, Joshua J Woodward, Daniel B Stetson, John Kenneth Baillie, Jane H Buckner, Michael Gale Jr, Ram Savan
Published 2021-08-01