Site-specific effects of neurosteroids on GABAA receptor activation and desensitization

by Yusuke Sugasawa, Wayland WL Cheng, John R Bracamontes, Zi-Wei Chen, Lei Wang, Allison L Germann, Spencer R Pierce, Thomas C Senneff, Kathiresan Krishnan, David E Reichert, Douglas F Covey, Gustav Akk, Alex S Evers
Published 2020-09-01

Transcriptome Survey of a Marine Food Fish: Asian Seabass (Lates calcarifer)

by Natascha M. Thevasagayam, Prakki S.R. Sridatta, Junhui Jiang, Amy Tong, Jolly M. Saju, Purushothaman Kathiresan, Hsiao Yuen Kwan, Si Yan Ngoh, Woei Chang Liew, Inna S. Kuznetsova, Xueyan Shen, Si Lok, Shubha Vij, László Orbán
Published 2015-06-01

Multiple functional neurosteroid binding sites on GABAA receptors.

by Zi-Wei Chen, John R Bracamontes, Melissa M Budelier, Allison L Germann, Daniel J Shin, Krishnan Kathiresan, Ming-Xing Qian, Brad Manion, Wayland W L Cheng, David E Reichert, Gustav Akk, Douglas F Covey, Alex S Evers
Published 2019-03-01

Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol.

by Sumeet A Khetarpal, Andrew C Edmondson, Avanthi Raghavan, Hemanth Neeli, Weijun Jin, Karen O Badellino, Serkalem Demissie, Alisa K Manning, Stephanie L DerOhannessian, Megan L Wolfe, L Adrienne Cupples, Mingyao Li, Sekar Kathiresan, Daniel J Rader
Published 2011-12-01

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

by Daniel I Chasman, Guillaume Paré, Samia Mora, Jemma C Hopewell, Gina Peloso, Robert Clarke, L Adrienne Cupples, Anders Hamsten, Sekar Kathiresan, Anders Mälarstig, José M Ordovas, Samuli Ripatti, Alex N Parker, Joseph P Miletich, Paul M Ridker
Published 2009-11-01

A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study

by Burtt Nöel P, Gianniny Lauren, Guiducci Candace, Surti Aarti, D'Agostino Ralph B, Demissie Serkalem, Manning Alisa K, Kathiresan Sekar, Melander Olle, Orho-Melander Marju, Arnett Donna K, Peloso Gina M, Ordovas Jose M, Cupples L Adrienne
Published 2007-09-01

Analysis of gene-gene interactions among common variants in candidate cardiovascular genes in coronary artery disease.

by Muntaser D Musameh, William Y S Wang, Christopher P Nelson, Carla Lluís-Ganella, Radoslaw Debiec, Isaac Subirana, Roberto Elosua, Anthony J Balmforth, Stephen G Ball, Alistair S Hall, Sekar Kathiresan, John R Thompson, Gavin Lucas, Nilesh J Samani, Maciej Tomaszewski
Published 2015-01-01

COVID-19-associated mucormycosis and treatments

by Vetriselvan Subramaniyan, Shivkanya Fuloria, Hari Kumar Darnal, Dhanalekshmi Unnikrishnan Meenakshi, Mahendran Sekar, Rusli Bin Nordin, Srikumar Chakravarthi, Kathiresan V Sathasivam, Shah Alam Khan, Yuan Seng Wu, Usha Kumari, Kalvatala Sudhakar, Rishabha Malviya, Vipin Kumar Sharma, Neeraj Kumar Fuloria
Published 2021-01-01

Nutrigenomic and Nutritional Analyses Reveal the Effects of Pelleted Feeds on Asian Seabass (Lates calcarifer).

by Si Yan Ngoh, Daniel Tan, Xueyan Shen, Purushothaman Kathiresan, Junhui Jiang, Woei Chang Liew, Natascha May Thevasagayam, Hsiao Yuen Kwan, Jolly M Saju, Sridatta R S Prakki, Chin Heng Goh, Hong Ching Wong, Tai Teck Chan, Miklós Mézes, László Orbán
Published 2015-01-01

Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.

by Aenne S Thormaehlen, Christian Schuberth, Hong-Hee Won, Peter Blattmann, Brigitte Joggerst-Thomalla, Susanne Theiss, Rosanna Asselta, Stefano Duga, Pier Angelica Merlini, Diego Ardissino, Eric S Lander, Stacey Gabriel, Daniel J Rader, Gina M Peloso, Rainer Pepperkok, Sekar Kathiresan, Heiko Runz
Published 2015-02-01

No yield penalty under favorable conditions paving the way for successful adoption of flood tolerant rice

by Manzoor H. Dar, Najam W. Zaidi, Showkat A. Waza, Satish B. Verulkar, T. Ahmed, P. K. Singh, S. K. Bardhan Roy, Bedanand Chaudhary, Rambaran Yadav, Mirza Mofazzal Islam, Khandakar M. Iftekharuddaula, J. K. Roy, R. M. Kathiresan, B. N. Singh, Uma S. Singh, Abdelbagi M. Ismail
Published 2018-06-01

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

by Akl C. Fahed, Minxian Wang, Julian R. Homburger, Aniruddh P. Patel, Alexander G. Bick, Cynthia L. Neben, Carmen Lai, Deanna Brockman, Anthony Philippakis, Patrick T. Ellinor, Christopher A. Cassa, Matthew Lebo, Kenney Ng, Eric S. Lander, Alicia Y. Zhou, Sekar Kathiresan, Amit V. Khera
Published 2020-08-01

Polygenic Risk Score Identifies Patients at Increased Risk for Abdominal Aortic Aneurysm and May Benefit from Ultrasound Screening

by Derek Klarin, Ozan Dikilitas, Brooke Wolford, Michael Levin, Ishan Paranjpe, Renae Judy, Julie Lynch, Themistocles L. Assimes, Yan Sun, Daniel Rader, Peter W. Wilson, Salvatore Scali, Scott Berceli, Sekar Kathiresan, Pradeep Natarajan, Girish Nadkarni, Cristen Willer, Iftikhar Kullo, Scott M. Damrauer, Philip Tsao
Published 2020-01-01

Genetic Structure and Population Demographic History of a Widespread Mangrove Plant Xylocarpus granatum J. Koenig across the Indo-West Pacific Region

by Yuki Tomizawa, Yoshiaki Tsuda, Mohd Nazre Saleh, Alison K. S. Wee, Koji Takayama, Takashi Yamamoto, Orlex Baylen Yllano, Severino G. Salmo III, Sarawood Sungkaew, Bayu Adjie, Erwin Ardli, Monica Suleiman, Nguyen Xuan Tung, Khin Khin Soe, Kathiresan Kandasamy, Takeshi Asakawa, Yasuyuki Watano, Shigeyuki Baba, Tadashi Kajita
Published 2017-12-01

Clinical characteristics and plasma lipids in subjects with familial combined hypolipidemia: a pooled analysis[S]

by Ilenia Minicocci, Sara Santini, Vito Cantisani, Nathan Stitziel, Sekar Kathiresan, Juan Antonio Arroyo, Gertrudis Martí, Livia Pisciotta, Davide Noto, Angelo B. Cefalù, Marianna Maranghi, Giancarlo Labbadia, Giovanni Pigna, Fabio Pannozzo, Fabrizio Ceci, Ester Ciociola, Stefano Bertolini, Sebastiano Calandra, Patrizia Tarugi, Maurizio Averna, Marcello Arca
Published 2013-12-01

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

by James P. Pirruccello, Alexander Bick, Minxian Wang, Mark Chaffin, Samuel Friedman, Jie Yao, Xiuqing Guo, Bharath Ambale Venkatesh, Kent D. Taylor, Wendy S. Post, Stephen Rich, Joao A. C. Lima, Jerome I. Rotter, Anthony Philippakis, Steven A. Lubitz, Patrick T. Ellinor, Amit V. Khera, Sekar Kathiresan, Krishna G. Aragam
Published 2020-05-01

An exome array study of the plasma metabolome

by Eugene P. Rhee, Qiong Yang, Bing Yu, Xuan Liu, Susan Cheng, Amy Deik, Kerry A. Pierce, Kevin Bullock, Jennifer E. Ho, Daniel Levy, Jose C. Florez, Sek Kathiresan, Martin G. Larson, Ramachandran S. Vasan, Clary B. Clish, Thomas J. Wang, Eric Boerwinkle, Christopher J. O’Donnell, Robert E. Gerszten
Published 2016-07-01

TUBB1 mutations cause thyroid dysgenesis associated with abnormal platelet physiology

by Athanasia Stoupa, Frédéric Adam, Dulanjalee Kariyawasam, Catherine Strassel, Sanjay Gawade, Gabor Szinnai, Alexandre Kauskot, Dominique Lasne, Carsten Janke, Kathiresan Natarajan, Alain Schmitt, Christine Bole‐Feysot, Patrick Nitschke, Juliane Léger, Fabienne Jabot‐Hanin, Frédéric Tores, Anita Michel, Arnold Munnich, Claude Besmond, Raphaël Scharfmann, François Lanza, Delphine Borgel, Michel Polak, Aurore Carré
Published 2018-12-01