TLR4-TAK1-p38 MAPK pathway and HDAC6 regulate the expression of sigma-1 receptors in rat primary cultured microglia

by Momoka Iwamoto, Yoki Nakamura, Masatoshi Takemura, Kazue Hisaoka-Nakashima, Norimitsu Morioka
Published 2020-09-01

Volume Transmission of Substance P in Striatum Induced by Intraplantar Formalin Injection Attenuates Nociceptive Responses via Activation of the Neurokinin 1 Receptor

by Yoki Nakamura, Hiroki Izumi, Takumi Shimizu, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Yoshihiro Nakata
Published 2013-01-01

Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes.

by Shuken Boku, Kazue Hisaoka-Nakashima, Shin Nakagawa, Akiko Kato, Naoto Kajitani, Takeshi Inoue, Ichiro Kusumi, Minoru Takebayashi
Published 2013-01-01

Neuropathic pain in rats with a partial sciatic nerve ligation is alleviated by intravenous injection of monoclonal antibody to high mobility group box-1.

by Yoki Nakamura, Norimitsu Morioka, Hiromi Abe, Fang Fang Zhang, Kazue Hisaoka-Nakashima, Keyue Liu, Masahiro Nishibori, Yoshihiro Nakata
Published 2013-01-01

History of the G Protein–Coupled Receptor (GPCR) Assays From Traditional to a State-of-the-Art Biosensor Assay

by Kanako Miyano, Yuka Sudo, Akinobu Yokoyama, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Minoru Takebayashi, Yoshihiro Nakata, Yoshikazu Higami, Yasuhito Uezono
Published 2014-04-01

Antidepressant acts on astrocytes leading to an increase in the expression of neurotrophic/growth factors: differential regulation of FGF-2 by noradrenaline.

by Naoto Kajitani, Kazue Hisaoka-Nakashima, Norimitsu Morioka, Mami Okada-Tsuchioka, Masahiro Kaneko, Miho Kasai, Chiyo Shibasaki, Yoshihiro Nakata, Minoru Takebayashi
Published 2012-01-01

Corticosterone Induces HMGB1 Release in Primary Cultured Rat Cortical Astrocytes: Involvement of Pannexin-1 and P2X7 Receptor-Dependent Mechanisms

by Kazue Hisaoka-Nakashima, Honami Azuma, Fumina Ishikawa, Yoki Nakamura, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Yoshihiro Nakata, Norimitsu Morioka
Published 2020-04-01

Pretreatment with High Mobility Group Box-1 Monoclonal Antibody Prevents the Onset of Trigeminal Neuropathy in Mice with a Distal Infraorbital Nerve Chronic Constriction Injury

by Takahiro Kochi, Yoki Nakamura, Simeng Ma, Kazue Hisaoka-Nakashima, Dengli Wang, Keyue Liu, Hidenori Wake, Masahiro Nishibori, Masahiro Irifune, Norimitsu Morioka
Published 2021-04-01