Impulsivity and Venturesomeness in an Adult ADHD Sample: Relation to Personality, Comorbidity, and Polygenic Risk

by Oliver Grimm, Heike Weber, Heike Weber, Sarah Kittel-Schneider, Sarah Kittel-Schneider, Thorsten M. Kranz, Christian P. Jacob, Klaus-Peter Lesch, Andreas Reif
Published 2020-12-01

Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice.

by Christa Hohoff, Ali Gorji, Sylvia Kaiser, Edith Willscher, Eberhard Korsching, Oliver Ambrée, Volker Arolt, Klaus-Peter Lesch, Norbert Sachser, Jürgen Deckert, Lars Lewejohann
Published 2013-01-01

Adult raphe-specific deletion of Lmx1b leads to central serotonin deficiency.

by Ning-Ning Song, Jian-Bo Xiu, Ying Huang, Jia-Yin Chen, Lei Zhang, Lise Gutknecht, Klaus Peter Lesch, He Li, Yu-Qiang Ding
Published 2011-01-01

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala

by Magdalena T. Weidner, Magdalena T. Weidner, Magdalena T. Weidner, Roy Lardenoije, Roy Lardenoije, Roy Lardenoije, Lars Eijssen, Lars Eijssen, Floriana Mogavero, Lilian P. M. T. De Groodt, Sandy Popp, Rupert Palme, Konrad U. Förstner, Konrad U. Förstner, Konrad U. Förstner, Tatyana Strekalova, Tatyana Strekalova, Tatyana Strekalova, Harry W. M. Steinbusch, Angelika G. Schmitt-Böhrer, Jeffrey C. Glennon, Jonas Waider, Daniel L. A. van den Hove, Daniel L. A. van den Hove, Klaus-Peter Lesch, Klaus-Peter Lesch, Klaus-Peter Lesch
Published 2019-05-01

Living in a dangerous world: the shaping of behavioral profile by early environment and 5-HTT genotype

by Rebecca S Heiming, Rebecca S Heiming, Friederike Jansen, Friederike Jansen, Lars Lewejohann, Lars Lewejohann, Sylvia Kaiser, Sylvia Kaiser, Angelika Schmitt, Klaus Peter Lesch, Norbert Sachser, Norbert Sachser
Published 2009-09-01

Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder?

by Martina Prelog, Deborah Hilligardt, Christian A Schmidt, Grzegorz K Przybylski, Johannes Leierer, Giovanni Almanzar, Nady El Hajj, Klaus-Peter Lesch, Volker Arolt, Peter Zwanzger, Thomas Haaf, Katharina Domschke
Published 2016-01-01

5-HTT deficiency affects neuroplasticity and increases stress sensitivity resulting in altered spatial learning performance in the Morris water maze but not in the Barnes maze.

by Margherita M Karabeg, Sandra Grauthoff, Sina Y Kollert, Magdalena Weidner, Rebecca S Heiming, Friederike Jansen, Sandy Popp, Sylvia Kaiser, Klaus-Peter Lesch, Norbert Sachser, Angelika G Schmitt, Lars Lewejohann
Published 2013-01-01

Serotonin transporter genotype modulates resting state and predator stress-induced amygdala perfusion in mice in a sex-dependent manner.

by Jann F Kolter, Markus F Hildenbrand, Sandy Popp, Stephan Nauroth, Julian Bankmann, Lisa Rother, Jonas Waider, Jürgen Deckert, Esther Asan, Peter M Jakob, Klaus-Peter Lesch, Angelika Schmitt-Böhrer
Published 2021-01-01

ASD-like behaviors, a dysregulated inflammatory response and decreased expression of PLP1 characterize mice deficient for sialyltransferase ST3GAL5

by Tatyana Strekalova, Evgeniy Svirin, Ekaterina Veniaminova, Ekaterina Kopeikina, Tatyana Veremeyko, Amanda W.Y. Yung, Andrey Proshin, Susanne Walitza, Daniel C. Anthony, Lee Wei Lim, Klaus-Peter Lesch, Eugene D. Ponomarev
Published 2021-10-01

Partially Defective Store Operated Calcium Entry and Hem(ITAM) Signaling in Platelets of Serotonin Transporter Deficient Mice.

by Karen Wolf, Attila Braun, Elizabeth J Haining, Yu-Lun Tseng, Peter Kraft, Michael K Schuhmann, Sanjeev K Gotru, Wenchun Chen, Heike M Hermanns, Guido Stoll, Klaus-Peter Lesch, Bernhard Nieswandt
Published 2016-01-01

Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification.

by Lise Gutknecht, Naozumi Araragi, Sören Merker, Jonas Waider, Frank M J Sommerlandt, Boris Mlinar, Gilda Baccini, Ute Mayer, Florian Proft, Michel Hamon, Angelika G Schmitt, Renato Corradetti, Laurence Lanfumey, Klaus-Peter Lesch
Published 2012-01-01

Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors.

by Gabriella Juhasz, Xenia Gonda, Gabor Hullam, Nora Eszlari, David Kovacs, Judit Lazary, Dorottya Pap, Peter Petschner, Rebecca Elliott, John Francis William Deakin, Ian Muir Anderson, Peter Antal, Klaus-Peter Lesch, Gyorgy Bagdy
Published 2015-01-01

Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelo...

by Maria Rosaria Vitale, Johanna Eva Maria Zöller, Charline Jansch, Anna Janz, Frank Edenhofer, Eva Klopocki, Daniel van den Hove, Tim Vanmierlo, Olga Rivero, Nael Nadif Kasri, Georg Christoph Ziegler, Klaus-Peter Lesch
Published 2021-03-01

Correction: Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene × Environment Interactions

by Daniel Louis Albert van den Hove, Sissi Brigitte Jakob, Karla-Gerlinde Schraut, Gunter Kenis, Angelika Gertrud Schmitt, Susanne Kneitz, Claus-Jürgen Scholz, Valentina Wiescholleck, Gabriela Ortega, Jos Prickaerts, Harry Steinbusch, Klaus-Peter Lesch
Published 2011-01-01

Differential effects of prenatal stress in 5-Htt deficient mice: towards molecular mechanisms of gene × environment interactions.

by Daniel Louis Albert van den Hove, Sissi Brigitte Jakob, Karla-Gerlinde Schraut, Gunter Kenis, Angelika Gertrud Schmitt, Susanne Kneitz, Claus-Jürgen Scholz, Valentina Wiescholleck, Gabriela Ortega, Jos Prickaerts, Harry Steinbusch, Klaus-Peter Lesch
Published 2011-01-01

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3

by Charline Jansch, Katharina Günther, Jonas Waider, Georg C. Ziegler, Andrea Forero, Sina Kollert, Evgeniy Svirin, Dirk Pühringer, Chee Keong Kwok, Reinhard Ullmann, Anna Maierhofer, Julia Flunkert, Thomas Haaf, Frank Edenhofer, Klaus-Peter Lesch
Published 2018-04-01

Correction: Differential Effects of Prenatal Stress in 5-Htt Deficient Mice: Towards Molecular Mechanisms of Gene × Environment Interactions.

by Daniel Louis Albert van den Hove, Sissi Brigitte Jakob, Karla-Gerlinde Schraut, Gunter Kenis, Angelika Gertrud Schmitt, Susanne Kneitz, Claus-Jürgen Scholz, Valentina Wiescholleck, Gabriela Ortega, Jos Prickaerts, Harry Steinbusch, Klaus-Peter Lesch
Published 2011-01-01

Cadherin 13: Human cis-Regulation and Selectively Altered Addiction Phenotypes and Cerebral Cortical Dopamine in Knockout Mice

by Jana Drgonova, Donna Walther, G. Luke Hartstein, Mohammad O. Bukhari, Michael H. Baumann, Jonathan Katz, F. Scott Hall, Elizabeth R. Arnold, Shaun Flax, Anthony Riley, Olga Rivero, Klaus-Peter Lesch, Juan Troncoso, Barbara Ranscht, George R. Uhl
Published 2016-08-01

A Common <i>CDH13</i> Variant Is Associated with Low Agreeableness and Neural Responses to Working Memory Tasks in ADHD

by Georg C. Ziegler, Ann-Christine Ehlis, Heike Weber, Maria Rosaria Vitale, Johanna E. M. Zöller, Hsing-Ping Ku, Miriam A. Schiele, Laura I. Kürbitz, Marcel Romanos, Paul Pauli, Raffael Kalisch, Peter Zwanzger, Katharina Domschke, Andreas J. Fallgatter, Andreas Reif, Klaus-Peter Lesch
Published 2021-08-01

The genetic architecture of human brainstem structures and their involvement in common brain disorders

by Torbjørn Elvsåshagen, Shahram Bahrami, Dennis van der Meer, Ingrid Agartz, Dag Alnæs, Deanna M. Barch, Ramona Baur-Streubel, Alessandro Bertolino, Mona K. Beyer, Giuseppe Blasi, Stefan Borgwardt, Birgitte Boye, Jan Buitelaar, Erlend Bøen, Elisabeth Gulowsen Celius, Simon Cervenka, Annette Conzelmann, David Coynel, Pasquale Di Carlo, Srdjan Djurovic, Sarah Eisenacher, Thomas Espeseth, Helena Fatouros-Bergman, Lena Flyckt, Barbara Franke, Oleksandr Frei, Barbara Gelao, Hanne Flinstad Harbo, Catharina A. Hartman, Asta Håberg, Dirk Heslenfeld, Pieter J. Hoekstra, Einar A. Høgestøl, Rune Jonassen, Erik G. Jönsson, Karolinska Schizophrenia Project (KaSP) consortium, Peter Kirsch, Iwona Kłoszewska, Trine Vik Lagerberg, Nils Inge Landrø, Stephanie Le Hellard, Klaus-Peter Lesch, Luigi A. Maglanoc, Ulrik F. Malt, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Torgeir Moberget, Jan Egil Nordvik, Lars Nyberg, Kevin S. O’ Connell, Jaap Oosterlaan, Marco Papalino, Andreas Papassotiropoulos, Paul Pauli, Giulio Pergola, Karin Persson, Dominique de Quervain, Andreas Reif, Jaroslav Rokicki, Daan van Rooij, Alexey A. Shadrin, André Schmidt, Emanuel Schwarz, Geir Selbæk, Hilkka Soininen, Piotr Sowa, Vidar M. Steen, Magda Tsolaki, Bruno Vellas, Lei Wang, Eric Westman, Georg C. Ziegler, Mathias Zink, Ole A. Andreassen, Lars T. Westlye, Tobias Kaufmann
Published 2020-08-01