A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer

by Fabiola N. Velazquez, Valentina Viscardi, Julia Montemage, Leiqing Zhang, Carolena Trocchia, Megan M. Delamont, Rasheed Ahmad, Yusuf A. Hannun, Lina M. Obeid, Ashley J. Snider
Published 2021-07-01

Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease.

by Ashley J Snider, Wahida H Ali, Jonathan A Sticca, Nicolas Coant, Amr M Ghaleb, Toshihiko Kawamori, Vincent W Yang, Yusuf A Hannun, Lina M Obeid
Published 2014-01-01

An intrinsic lipid-binding interface controls sphingosine kinase 1 function[S]

by Michael J. Pulkoski-Gross, Meredith L. Jenkins, Jean-Philip Truman, Mohamed F. Salama, Christopher J. Clarke, John E. Burke, Yusuf A. Hannun, Lina M. Obeid
Published 2018-03-01

A deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulation.

by Lihong Zhao, Stefka D Spassieva, Thomas J Jucius, Leonard D Shultz, H Elizabeth Shick, Wendy B Macklin, Yusuf A Hannun, Lina M Obeid, Susan L Ackerman
Published 2011-05-01

Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells

by Fatema Al-Rashed, Zunair Ahmad, Ashley J. Snider, Reeby Thomas, Shihab Kochumon, Motasem Melhem, Sardar Sindhu, Lina M. Obeid, Fahd Al-Mulla, Yusuf A. Hannun, Rasheed Ahmad
Published 2021-04-01

Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells

by Chih-Li Lin, Ruijuan Xu, Jae Kyo Yi, Fang Li, Jiang Chen, Evan C. Jones, Jordan B. Slutsky, Liqun Huang, Basil Rigas, Jian Cao, Xiaoming Zhong, Ashley J. Snider, Lina M. Obeid, Yusuf A. Hannun, Cungui Mao
Published 2017-11-01

Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.

by Kai Wang, Ruijuan Xu, Jennifer Schrandt, Prithvi Shah, Yong Z Gong, Chet Preston, Louis Wang, Jae Kyo Yi, Chih-Li Lin, Wei Sun, Demetri D Spyropoulos, Soyoung Rhee, Mingsong Li, Jie Zhou, Shaoyu Ge, Guofeng Zhang, Ashley J Snider, Yusuf A Hannun, Lina M Obeid, Cungui Mao
Published 2015-10-01

Correction: Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.

by Kai Wang, Ruijuan Xu, Jennifer Schrandt, Prithvi Shah, Yong Z Gong, Chet Preston, Louis Wang, Jae Kyo Yi, Chih-Li Lin, Wei Sun, Demetri D Spyropoulos, Soyoung Rhee, Mingsong Li, Jie Zhou, Shaoyu Ge, Guofeng Zhang, Ashley J Snider, Yusuf A Hannun, Lina M Obeid, Cungui Mao
Published 2018-01-01

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury

by Tess V. Dupre, Mark A. Doll, Parag P. Shah, Cierra N. Sharp, Deanna Siow, Judit Megyesi, James Shayman, Alicja Bielawska, Jacek Bielawski, Levi J. Beverly, Maria Hernandez-Corbacho, Christopher J. Clarke, Ashley J. Snider, Rick G. Schnellmann, Lina M. Obeid, Yusuf A. Hannun, Leah J. Siskind
Published 2017-07-01