HIV-1 subtype C unproductively infects human cardiomyocytes in vitro and induces apoptosis mitigated by an anti-Gp120 aptamer.

by Walter R Lopes de Campos, Nthato Chirwa, Grace London, Lia S Rotherham, Lynn Morris, Bongani M Mayosi, Makobetsa Khati
Published 2014-01-01

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage.

by Lucia Reh, Carsten Magnus, Claus Kadelka, Denise Kühnert, Therese Uhr, Jacqueline Weber, Lynn Morris, Penny L Moore, Alexandra Trkola
Published 2018-01-01

Production and Immunogenicity of Soluble Plant-Produced HIV-1 Subtype C Envelope gp140 Immunogens

by Emmanuel Margolin, Emmanuel Margolin, Rosamund Chapman, Ann E. Meyers, Michiel T. van Diepen, Phindile Ximba, Phindile Ximba, Tandile Hermanus, Tandile Hermanus, Carol Crowther, Carol Crowther, Brandon Weber, Lynn Morris, Lynn Morris, Anna-Lise Williamson, Anna-Lise Williamson, Edward P. Rybicki, Edward P. Rybicki
Published 2019-10-01

Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes.

by Constantinos Kurt Wibmer, Jinal N Bhiman, Elin S Gray, Nancy Tumba, Salim S Abdool Karim, Carolyn Williamson, Lynn Morris, Penny L Moore
Published 2013-10-01

Infection of Chinese Rhesus Monkeys with a Subtype C SHIV Resulted in Attenuated In Vivo Viral Replication Despite Successful Animal-to-Animal Serial Passages

by Gerald K. Chege, Craig H. Adams, Alana T. Keyser, Valerie Bekker, Lynn Morris, Francois J. Villinger, Anna-Lise Williamson, Rosamund E. Chapman
Published 2021-03-01

Adherence to drug-refill is a useful early warning indicator of virologic and immunologic failure among HIV patients on first-line ART in South Africa.

by Ziad El-Khatib, Ziad El-Khatib, David Katzenstein, Gaetano Marrone, Fatima Laher, Lerato Mohapi, Max Petzold, Lynn Morris, Anna Mia Ekström
Published 2011-03-01

The adjuvant AlhydroGel elicits higher antibody titres than AddaVax when combined with HIV-1 subtype C gp140 from CAP256.

by Michiel T van Diepen, Rosamund Chapman, Penny L Moore, Emmanuel Margolin, Tandile Hermanus, Lynn Morris, Phindile Ximba, Edward P Rybicki, Anna-Lise Williamson
Published 2018-01-01

Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children

by Julia Roider, Julia Roider, Julia Roider, Julia Roider, Julia Roider, J. Zachary Porterfield, J. Zachary Porterfield, Paul Ogongo, Paul Ogongo, Paul Ogongo, Maximilian Muenchhoff, Maximilian Muenchhoff, Maximilian Muenchhoff, Maximilian Muenchhoff, Emily Adland, Andreas Groll, Lynn Morris, Lynn Morris, Lynn Morris, Penny L. Moore, Penny L. Moore, Penny L. Moore, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Henrik Kløverpris, Henrik Kløverpris, Henrik Kløverpris, Philip J. R. Goulder, Alasdair Leslie, Alasdair Leslie
Published 2019-07-01

Prevalence of HIV-1 drug resistance amongst newly diagnosed HIV-infected infants age 4–8 weeks, enrolled in three nationally representative PMTCT effectiveness surveys, South Afric...

by Gillian M. Hunt, Johanna Ledwaba, Anna Salimo, Monalisa Kalimashe, Thu-Ha Dinh, Debra Jackson, Gayle Sherman, Adrian Puren, Nobubelo K. Ngandu, Carl Lombard, Lynn Morris, Ameena Goga
Published 2019-09-01

HIV-specific Fc effector function early in infection predicts the development of broadly neutralizing antibodies.

by Simone I Richardson, Amy W Chung, Harini Natarajan, Batsirai Mabvakure, Nonhlanhla N Mkhize, Nigel Garrett, Salim Abdool Karim, Penny L Moore, Margaret E Ackerman, Galit Alter, Lynn Morris
Published 2018-04-01

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

by Julia Roider, Julia Roider, Julia Roider, Julia Roider, Takashi Maehara, Abigail Ngoepe, Duran Ramsuran, Maximilian Muenchhoff, Maximilian Muenchhoff, Emily Adland, Toby Aicher, Toby Aicher, Toby Aicher, Samuel W. Kazer, Samuel W. Kazer, Samuel W. Kazer, Pieter Jooste, Farina Karim, Warren Kuhn, Alex K. Shalek, Alex K. Shalek, Alex K. Shalek, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Thumbi Ndung'u, Lynn Morris, Lynn Morris, Lynn Morris, Penny L. Moore, Penny L. Moore, Penny L. Moore, Shiv Pillai, Henrik Kløverpris, Henrik Kløverpris, Henrik Kløverpris, Philip Goulder, Philip Goulder, Alasdair Leslie, Alasdair Leslie
Published 2018-09-01

IgG3 enhances neutralization potency and Fc effector function of an HIV V2-specific broadly neutralizing antibody.

by Simone I Richardson, Bronwen E Lambson, Andrew R Crowley, Arman Bashirova, Cathrine Scheepers, Nigel Garrett, Salim Abdool Karim, Nonhlanhla N Mkhize, Mary Carrington, Margaret E Ackerman, Penny L Moore, Lynn Morris
Published 2019-12-01

Randomized trial of time-limited interruptions of protease inhibitor-based antiretroviral therapy (ART) vs. continuous therapy for HIV-1 infection.

by Cynthia Firnhaber, Livio Azzoni, Andrea S Foulkes, Robert Gross, Xiangfan Yin, Desiree Van Amsterdam, Doreen Schulze, Deborah K Glencross, Wendy Stevens, Gillian Hunt, Lynn Morris, Lawrence Fox, Ian Sanne, Luis J Montaner
Published 2011-01-01

Randomized Cross-Sectional Study to Compare HIV-1 Specific Antibody and Cytokine Concentrations in Female Genital Secretions Obtained by Menstrual Cup and Cervicovaginal Lavage.

by Derseree Archary, Lenine J Liebenberg, Lise Werner, Sahil Tulsi, Nelisile Majola, Nivashnee Naicker, Sarah Dlamini, Thomas J Hope, Natasha Samsunder, Salim S Abdool Karim, Lynn Morris, Jo-Ann S Passmore, Nigel J Garrett
Published 2015-01-01

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

by Jenniffer M. Mabuka, Jenniffer M. Mabuka, Jenniffer M. Mabuka, Anne-Sophie Dugast, Daniel M. Muema, Daniel M. Muema, Daniel M. Muema, Tarylee Reddy, Yathisha Ramlakhan, Yathisha Ramlakhan, Zelda Euler, Nasreen Ismail, Amber Moodley, Amber Moodley, Krista L. Dong, Krista L. Dong, Lynn Morris, Lynn Morris, Bruce D. Walker, Bruce D. Walker, Bruce D. Walker, Bruce D. Walker, Galit Alter, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u, Thumbi Ndung’u
Published 2017-09-01

Sipuleucel‐T associated inflammatory cardiomyopathy: a case report and observations from a large pharmacovigilance database

by Melissa Y.Y. Moey, Rahim A. Jiwani, Kotaro Takeda, Karyn Prenshaw, R. Wayne Kreeger, John Inzerillo, Darla K. Liles, C. Bogdan Marcu, Bénédicte Lebrun‐Vignes, D. Lynn Morris, Sivakumar Ardhanari, Joe‐Elie Salem
Published 2021-08-01

Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.

by Penny L Moore, Nthabeleng Ranchobe, Bronwen E Lambson, Elin S Gray, Eleanor Cave, Melissa-Rose Abrahams, Gama Bandawe, Koleka Mlisana, Salim S Abdool Karim, Carolyn Williamson, Lynn Morris, CAPRISA 002 Study, NIAID Center for HIV/AIDS Vaccine Immunology (CHAVI)
Published 2009-09-01

Establishing a cohort at high risk of HIV infection in South Africa: challenges and experiences of the CAPRISA 002 acute infection study.

by Francois van Loggerenberg, Koleka Mlisana, Carolyn Williamson, Sara C Auld, Lynn Morris, Clive M Gray, Quarraisha Abdool Karim, Anneke Grobler, Nomampondo Barnabas, Itua Iriogbe, Salim S Abdool Karim, CAPRISA 002 Acute Infection Study Team, CAPRISA 002 Acute Infection Study Team
Published 2008-04-01

International network for comparison of HIV neutralization assays: the NeutNet report II.

by Leo Heyndrickx, Alan Heath, Enas Sheik-Khalil, Jose Alcami, Vera Bongertz, Marianne Jansson, Mauro Malnati, David Montefiori, Christiane Moog, Lynn Morris, Saladin Osmanov, Victoria Polonis, Meghna Ramaswamy, Quentin Sattentau, Monica Tolazzi, Hanneke Schuitemaker, Betty Willems, Terri Wrin, Eva Maria Fenyö, Gabriella Scarlatti
Published 2012-01-01

Effect of HIV Envelope Vaccination on the Subsequent Antibody Response to HIV Infection

by Zanele Ditse, Nonhlanhla N. Mkhize, Michael Yin, Michael Keefer, David C. Montefiori, Georgia D. Tomaras, Gavin Churchyard, Kenneth H. Mayer, Shelly Karuna, Cecilia Morgan, Linda-Gail Bekker, Koleka Mlisana, Glenda Gray, Zoe Moodie, Peter Gilbert, Penny L. Moore, Carolyn Williamson, Lynn Morris
Published 2020-01-01