Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.

by Denise L Driscoll, Arijit Chakravarty, Doug Bowman, Vaishali Shinde, Kerri Lasky, Judy Shi, Tricia Vos, Bradley Stringer, Ben Amidon, Natalie D'Amore, Marc L Hyer
Published 2014-01-01

Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma.

by Christina L Kress, Marina Konopleva, Vanesa Martínez-García, Maryla Krajewska, Sophie Lefebvre, Marc L Hyer, Teresa McQueen, Michael Andreeff, John C Reed, Juan M Zapata
Published 2007-06-01