Jacalin-Activated Macrophages Exhibit an Antitumor Phenotype

by Cláudia Danella Polli, Luciana Pereira Ruas, Luciana Chain Veronez, Thais Herrero Geraldino, Fabiana Rossetto de Morais, Maria Cristina Roque-Barreira, Gabriela Pereira-da-Silva
Published 2016-01-01

Eutirucallin, a RIP-2 type lectin from the latex of Euphorbia tirucalli L. presents proinflammatory properties.

by Sanzio Silva Santana, Margareth Leitão Gennari-Cardoso, Fernanda Caroline Carvalho, Maria Cristina Roque-Barreira, André da Silva Santiago, Fátima Cerqueira Alvim, Carlos Priminho Pirovani
Published 2014-01-01

HU-Lacking Mutants of Salmonella enterica Enteritidis Are Highly Attenuated and Can Induce Protection in Murine Model of Infection

by Guilherme P. Milanez, Catierine H. Werle, Mariene R. Amorim, Rafael A. Ribeiro, Luiz H. S. Tibo, Maria Cristina Roque-Barreira, Aline F. Oliveira, Marcelo Brocchi
Published 2018-08-01

Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice.

by Camila Figueiredo Pinzan, Aline Sardinha-Silva, Fausto Almeida, Livia Lai, Carla Duque Lopes, Elaine Vicente Lourenço, Ademilson Panunto-Castelo, Stephen Matthews, Maria Cristina Roque-Barreira
Published 2015-01-01

Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity.

by Luciana Pereira Ruas, Emerson Soares Bernardes, Marise Lopes Fermino, Leandro Licursi de Oliveira, Daniel K Hsu, Fu-Tong Liu, Roger Chammas, Maria-Cristina Roque-Barreira
Published 2009-01-01

Recognition of TLR2 N-glycans: critical role in ArtinM immunomodulatory activity.

by Vania Sammartino Mariano, Andre Luiz Zorzetto-Fernandes, Thiago Aparecido da Silva, Luciana Pereira Ruas, Lilian L Nohara, Igor Correia de Almeida, Maria Cristina Roque-Barreira
Published 2014-01-01

Influence of N-glycosylation on the morphogenesis and growth of Paracoccidioides brasiliensis and on the biological activities of yeast proteins.

by Fausto Bruno Dos Reis Almeida, Fernanda Caroline Carvalho, Vânia Sammartino Mariano, Ana Claudia Paiva Alegre, Roberto do Nascimento Silva, Ebert Seixas Hanna, Maria Cristina Roque-Barreira
Published 2011-01-01

Paracoccin distribution supports its role in Paracoccidioides brasiliensis growth and dimorphic transformation.

by Aline Ferreira Oliveira, Fabricio Freitas Fernandes, Vânia Sammartino Mariano, Fausto Almeida, Luciana Pereira Ruas, Leandro Licursi Oliveira, Constance Oliver, Maria Celia Jamur, Maria Cristina Roque-Barreira
Published 2017-01-01

Lectins from Synadenium carinatum (ScLL) and Artocarpus heterophyllus (ArtinM) are able to induce beneficial immunomodulatory effects in a murine model for treatment of Toxoplasma...

by Leandro Peixoto Ferreira Souza, Eliézer Lucas Pires Ramos, Silas Silva Santana, Murilo Vieira Silva, Fernanda Maria Santiago, Tiago WP Mineo, Maria Cristina Roque-Barreira, José Roberto Mineo
Published 2016-11-01

Galectin-3 Inhibits Paracoccidioides brasiliensis Growth and Impacts Paracoccidioidomycosis through Multiple Mechanisms

by Otavio Hatanaka, Caroline Patini Rezende, Pedro Moreno, Fabrício Freitas Fernandes, Patrícia Kellen Martins Oliveira Brito, Roberto Martinez, Carolina Coelho, Maria Cristina Roque-Barreira, Arturo Casadevall, Fausto Almeida
Published 2019-04-01

Expression of Hsp60 and its cell location in Paracoccidioides brasiliensis

by Fabrício Freitas Fernandes, Nayla S. Pitangui, Gabriela Peron, Clarissa X. R. Valim, Vívian M. Mazucato, Aline F. Oliveira, Thiago A. da Silva, Maria-Cristina Roque-Barreira, Ademilson Panunto-Castelo

LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation.

by Marise Lopes Fermino, Claudia Danella Polli, Karina Alves Toledo, Fu-Tong Liu, Dan K Hsu, Maria Cristina Roque-Barreira, Gabriela Pereira-da-Silva, Emerson Soares Bernardes, Lise Halbwachs-Mecarelli
Published 2011-01-01

Systemic effects in naïve mice injected with immunomodulatory lectin ArtinM.

by Patrícia Kellen Martins Oliveira Brito, Thiago Eleutério Gonçalves, Fabrício Freitas Fernandes, Camila Botelho Miguel, Wellington Francisco Rodrigues, Javier Emílio Lazo Chica, Maria Cristina Roque-Barreira, Thiago Aparecido da Silva
Published 2017-01-01

Therapeutic administration of recombinant Paracoccin confers protection against paracoccidioides brasiliensis infection: involvement of TLRs.

by Ana Claudia Paiva Alegre-Maller, Flávia Costa Mendonça, Thiago Aparecido da Silva, Aline Ferreira Oliveira, Mateus Silveira Freitas, Ebert Seixas Hanna, Igor C Almeida, Nicholas J Gay, Maria Cristina Roque-Barreira
Published 2014-12-01

Detrimental Effect of Fungal 60-kDa Heat Shock Protein on Experimental Paracoccidioides brasiliensis Infection.

by Fabrício Freitas Fernandes, Leandro Licursi de Oliveira, Taise Natali Landgraf, Gabriela Peron, Marcelo Vieira Costa, Arlete A M Coelho-Castelo, Vânia L D Bonato, Maria-Cristina Roque-Barreira, Ademilson Panunto-Castelo
Published 2016-01-01

Effect of ArtinM on Human Blood Cells During Infection With Paracoccidioides brasiliensis

by Luciana P. Ruas, Livia M. Genaro, Amauri S. Justo-Junior, Lilian O. Coser, Lívia F. de Castro, Plinio Trabasso, Ronei L. Mamoni, Ronei L. Mamoni, Maria-Cristina Roque-Barreira, Maria-Heloisa S. L. Blotta
Published 2018-05-01

Impact of Paracoccin Gene Silencing on Paracoccidioides brasiliensis Virulence

by Fabrício F. Fernandes, Aline F. Oliveira, Taise N. Landgraf, Cristina Cunha, Agostinho Carvalho, Patríícia E. Vendruscolo, Relber A. Goncales, Fausto Almeida, Thiago A. da Silva, Fernando Rodrigues, Maria Cristina Roque-Barreira, Christina A. Cuomo, Antonio Cassone
Published 2017-07-01

Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects

by Fausto Almeida, Julie M. Wolf, Thiago Aparecido da Silva, Carlos M. DeLeon-Rodriguez, Caroline Patini Rezende, André Moreira Pessoni, Fabrício Freitas Fernandes, Rafael Silva-Rocha, Roberto Martinez, Marcio L. Rodrigues, Maria Cristina Roque-Barreira, Arturo Casadevall
Published 2017-12-01

Characterization of PbPga1, an antigenic GPI-protein in the pathogenic fungus Paracoccidioides brasiliensis.

by Clarissa X R Valim, Luiz Roberto Basso, Fausto B dos Reis Almeida, Thaila Fernanda Reis, André Ricardo Lima Damásio, Luisa Karla Arruda, Roberto Martinez, Maria Cristina Roque-Barreira, Constance Oliver, Maria Célia Jamur, Paulo Sergio Rodrigues Coelho
Published 2012-01-01

Receptor Heterodimerization and Co-Receptor Engagement in TLR2 Activation Induced by MIC1 and MIC4 from <em>Toxoplasma gondii</em>

by Flávia Costa Mendonça-Natividade, Carla Duque Lopes, Rafael Ricci-Azevedo, Aline Sardinha-Silva, Camila Figueiredo Pinzan, Ana Claudia Paiva Alegre-Maller, Lilian L. Nohara, Alan B. Carneiro, Ademilson Panunto-Castelo, Igor C. Almeida, Maria Cristina Roque-Barreira
Published 2019-10-01