Immune signature as predictive marker for response to checkpoint inhibitor immunotherapy and overall survival in melanoma

by Franziska K. Krebs, Emily R. Trzeciak, Sophia Zimmer, Deniz Özistanbullu, Heidrun Mitzel‐Rink, Markus Meissner, Stephan Grabbe, Carmen Loquai, Andrea Tuettenberg
Published 2021-03-01

Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo [version 1; referees: 1 approved, 2 approved wit...

by Simon Gras, Allison Jackson, Stuart Woods, Gurman Pall, Jamie Whitelaw, Jacqueline M. Leung, Gary E. Ward, Craig W. Roberts, Markus Meissner
Published 2017-05-01

Parasites lacking the micronemal protein MIC2 are deficient in surface attachment and host cell egress, but remain virulent in vivo [version 2; referees: 1 approved, 2 approved wit...

by Simon Gras, Allison Jackson, Stuart Woods, Gurman Pall, Jamie Whitelaw, Jacqueline M. Leung, Gary E. Ward, Craig W. Roberts, Markus Meissner
Published 2017-07-01

Rab11A regulates dense granule transport and secretion during Toxoplasma gondii invasion of host cells and parasite replication.

by Kannan Venugopal, Sylia Chehade, Elisabeth Werkmeister, Nicolas Barois, Javier Periz, Frank Lafont, Isabelle Tardieux, Jamal Khalife, Gordon Langsley, Markus Meissner, Sabrina Marion
Published 2020-05-01

Rab11A-controlled assembly of the inner membrane complex is required for completion of apicomplexan cytokinesis.

by Carolina Agop-Nersesian, Bernina Naissant, Fathia Ben Rached, Manuel Rauch, Angelika Kretzschmar, Sabine Thiberge, Robert Menard, David J P Ferguson, Markus Meissner, Gordon Langsley
Published 2009-01-01

The toxoplasma Acto-MyoA motor complex is important but not essential for gliding motility and host cell invasion.

by Saskia Egarter, Nicole Andenmatten, Allison J Jackson, Jamie A Whitelaw, Gurman Pall, Jennifer Ann Black, David J P Ferguson, Isabelle Tardieux, Alex Mogilner, Markus Meissner
Published 2014-01-01

Conditional U1 Gene Silencing in Toxoplasma gondii.

by Manuela S Pieperhoff, Gurman S Pall, Elena Jiménez-Ruiz, Sujaan Das, Carmen Melatti, Matthew Gow, Eleanor H Wong, Joanne Heng, Sylke Müller, Michael J Blackman, Markus Meissner
Published 2015-01-01

Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis.

by Lina Tawk, Jean-François Dubremetz, Philippe Montcourrier, Gaëtan Chicanne, Fabrice Merezegue, Véronique Richard, Bernard Payrastre, Markus Meissner, Henri J Vial, Christian Roy, Kai Wengelnik, Maryse Lebrun
Published 2011-02-01

Toxoplasma gondii F-actin forms an extensive filamentous network required for material exchange and parasite maturation

by Javier Periz, Jamie Whitelaw, Clare Harding, Simon Gras, Mario Igor Del Rosario Minina, Fernanda Latorre-Barragan, Leandro Lemgruber, Madita Alice Reimer, Robert Insall, Aoife Heaslip, Markus Meissner
Published 2017-03-01

C6 Ceramide (d18:1/6:0) as a Novel Treatment of Cutaneous T Cell Lymphoma

by Raphael Wilhelm, Timon Eckes, Gergely Imre, Stefan Kippenberger, Markus Meissner, Dominique Thomas, Sandra Trautmann, Jean-Philippe Merlio, Edith Chevret, Roland Kaufmann, Josef Pfeilschifter, Alexander Koch, Manuel Jäger
Published 2021-01-01

An overexpression screen of Toxoplasma gondii Rab-GTPases reveals distinct transport routes to the micronemes.

by Katrin Kremer, Dirk Kamin, Eva Rittweger, Jonathan Wilkes, Halley Flammer, Sabine Mahler, Joanne Heng, Christopher J Tonkin, Gordon Langsley, Stefan W Hell, Vernon B Carruthers, David J P Ferguson, Markus Meissner
Published 2013-03-01

DNA methylation-based prediction of response to immune checkpoint inhibition in metastatic melanoma

by Bastian Schilling, Sascha Tierling, Jörn Walter, Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Pia S. Zeiner, Patrick N. Harter
Published 2021-07-01

Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma

by Jens von der Grün, Ria Winkelmann, Markus Meissner, Ulrike Wieland, Steffi Silling, Daniel Martin, Emmanouil Fokas, Emmanouil Fokas, Emmanouil Fokas, Claus Rödel, Claus Rödel, Claus Rödel, Franz Rödel, Franz Rödel, Franz Rödel, Panagiotis Balermpas, Panagiotis Balermpas, Panagiotis Balermpas, Panagiotis Balermpas
Published 2019-01-01

Combined immune checkpoint blockade for metastatic uveal melanoma: a retrospective, multi-center study

by Markus V. Heppt, Teresa Amaral, Katharina C. Kähler, Lucie Heinzerling, Jessica C. Hassel, Markus Meissner, Nicole Kreuzberg, Carmen Loquai, Lydia Reinhardt, Jochen Utikal, Evelyn Dabrowski, Anja Gesierich, Claudia Pföhler, Patrick Terheyden, Kai-Martin Thoms, Lisa Zimmer, Thomas K. Eigentler, Michael C. Kirchberger, Henner M. Stege, Friedegund Meier, Max Schlaak, Carola Berking
Published 2019-11-01

Immune Checkpoint Blockade for Metastatic Uveal Melanoma: Patterns of Response and Survival According to the Presence of Hepatic and Extrahepatic Metastasis

by Elias A. T. Koch, Anne Petzold, Anja Wessely, Edgar Dippel, Anja Gesierich, Ralf Gutzmer, Jessica C. Hassel, Sebastian Haferkamp, Bettina Hohberger, Katharina C. Kähler, Harald Knorr, Nicole Kreuzberg, Ulrike Leiter, Carmen Loquai, Friedegund Meier, Markus Meissner, Peter Mohr, Claudia Pföhler, Farnaz Rahimi, Dirk Schadendorf, Beatrice Schell, Max Schlaak, Patrick Terheyden, Kai-Martin Thoms, Beatrice Schuler-Thurner, Selma Ugurel, Jens Ulrich, Jochen Utikal, Michael Weichenthal, Fabian Ziller, Carola Berking, Markus V. Heppt, on behalf of the German Dermatologic Cooperative Oncology Group (DeCOG, Committee Ocular Melanoma)
Published 2021-07-01