Optimized quantification of fragmented, free circulating DNA in human blood plasma using a calibrated duplex real-time PCR.

by Martin Horlitz, Annabelle Lucas, Markus Sprenger-Haussels
Published 2009-01-01

Multimodal Targeted Deep Sequencing of Circulating Tumor Cells and Matched Cell-Free DNA Provides a More Comprehensive Tool to Identify Therapeutic Targets in Metastatic Breast Can...

by Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2020-04-01

Cell-Free DNA Variant Sequencing Using CTC-Depleted Blood for Comprehensive Liquid Biopsy Testing in Metastatic Breast Cancer

by Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Mitra Tewes, Pawel Mach, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2019-02-01

Characterization of RNA from Exosomes and Other Extracellular Vesicles Isolated by a Novel Spin Column-Based Method.

by Daniel Enderle, Alexandra Spiel, Christine M Coticchia, Emily Berghoff, Romy Mueller, Martin Schlumpberger, Markus Sprenger-Haussels, Jonathan M Shaffer, Eric Lader, Johan Skog, Mikkel Noerholm
Published 2015-01-01

Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer

by Corinna Keup, Vinay Suryaprakash, Siegfried Hauch, Markus Storbeck, Peter Hahn, Markus Sprenger-Haussels, Hans-Christian Kolberg, Mitra Tewes, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Published 2021-05-01

Multicenter Evaluation of Independent High-Throughput and RT-qPCR Technologies for the Development of Analytical Workflows for Circulating miRNA Analysis

by Anna Babayan, Martin H. D. Neumann, Andrei Herdean, Jonathan M. Shaffer, Melanie Janning, Franca Kobus, Sonja Loges, Francesca Di Pasquale, Mikael Kubista, Martin Schlumpberger, Rita Lampignano, Thomas Krahn, Thomas Schlange, Markus Sprenger-Haussels, Klaus Pantel, Vera Kloten
Published 2020-05-01

Pre‐analytical factors affecting the establishment of a single tube assay for multiparameter liquid biopsy detection in melanoma patients

by Svenja Schneegans, Lelia Lück, Katharina Besler, Leonie Bluhm, Julia‐Christina Stadler, Janina Staub, Rüdiger Greinert, Beate Volkmer, Mikael Kubista, Christoffer Gebhardt, Alexander Sartori, Darryl Irwin, Elina Serkkola, Taija afHällström, Evi Lianidou, Markus Sprenger‐Haussels, Melanie Hussong, Peter Mohr, Stefan W. Schneider, Jonathan Shaffer, Klaus Pantel, Harriet Wikman
Published 2020-05-01

Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling

by Sabrina Weber, Benjamin Spiegl, Samantha O. Perakis, Christine M. Ulz, Peter M. Abuja, Karl Kashofer, Paul van der Leest, Maria Aguirre Azpurua, Menno Tamminga, Dan Brudzewsky, Dominic G. Rothwell, Sumitra Mohan, Alexander Sartori, Rita Lampignano, Yves Konigshofer, Markus Sprenger-Haussels, Harriet Wikman, Inger R. Bergheim, Vera Kloten, Ed Schuuring, Michael R. Speicher, Ellen Heitzer
Published 2020-06-01