Identification of potential sites for tryptophan oxidation in recombinant antibodies using tert-butylhydroperoxide and quantitative LC-MS.

by Miriam Hensel, Rebecca Steurer, Juergen Fichtl, Carsten Elger, Frank Wedekind, Andreas Petzold, Tilman Schlothauer, Michael Molhoj, Dietmar Reusch, Patrick Bulau
Published 2011-01-01

Simultaneous assessment of Asp isomerization and Asn deamidation in recombinant antibodies by LC-MS following incubation at elevated temperatures.

by Katharina Diepold, Katrin Bomans, Michael Wiedmann, Boris Zimmermann, Andreas Petzold, Tilman Schlothauer, Robert Mueller, Bernd Moritz, Jan Olaf Stracke, Michael Mølhøj, Dietmar Reusch, Patrick Bulau
Published 2012-01-01

Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions.

by Jasmin F Sydow, Florian Lipsmeier, Vincent Larraillet, Maximiliane Hilger, Bjoern Mautz, Michael Mølhøj, Jan Kuentzer, Stefan Klostermann, Juergen Schoch, Hans R Voelger, Joerg T Regula, Patrick Cramer, Apollon Papadimitriou, Hubert Kettenberger
Published 2014-01-01

Identification and monitoring of host cell proteins by mass spectrometry combined with high performance immunochemistry testing.

by Katrin Bomans, Antje Lang, Veronika Roedl, Lisa Adolf, Kyrillos Kyriosoglou, Katharina Diepold, Gabriele Eberl, Michael Mølhøj, Ulrike Strauss, Christian Schmalz, Rudolf Vogel, Dietmar Reusch, Harald Wegele, Michael Wiedmann, Patrick Bulau
Published 2013-01-01