Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation

by Céline Vandamme, Rebecca Xicluna, Leslie Hesnard, Marie Devaux, Nicolas Jaulin, Mickaël Guilbaud, Johanne Le Duff, Célia Couzinié, Philippe Moullier, Xavier Saulquin, Oumeya Adjali
Published 2020-01-01

Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates.

by Caroline Le Guiner, Knut Stieger, Alice Toromanoff, Mickaël Guilbaud, Alexandra Mendes-Madeira, Marie Devaux, Lydie Guigand, Yan Cherel, Philippe Moullier, Fabienne Rolling, Oumeya Adjali
Published 2014-01-01

AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation

by Gwladys Gernoux, Mickaël Guilbaud, Marie Devaux, Malo Journou, Virginie Pichard, Nicolas Jaulin, Adrien Léger, Johanne Le Duff, Jack-Yves Deschamps, Caroline Le Guiner, Philippe Moullier, Yan Cherel, Oumeya Adjali
Published 2021-03-01

Generation and in vivo evaluation of IL10-treated dendritic cells in a nonhuman primate model of AAV-based gene transfer

by Aurélie Moreau, Céline Vandamme, Mercedes Segovia, Marie Devaux, Mickaël Guilbaud, Gaëlle Tilly, Nicolas Jaulin, Johanne Le Duff, Yan Cherel, Jack-Yves Deschamps, Ignacio Anegon, Philippe Moullier, Maria Cristina Cuturi, Oumeya Adjali
Published 2014-01-01