Angiotensin II Induces Oxidative Stress and Endothelial Dysfunction in Mouse Ophthalmic Arteries via Involvement of AT1 Receptors and NOX2

by Michael Birk, Ewa Baum, Jenia Kouchek Zadeh, Caroline Manicam, Norbert Pfeiffer, Andreas Patzak, Johanna Helmstädter, Sebastian Steven, Marin Kuntic, Andreas Daiber, Adrian Gericke
Published 2021-08-01

Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.

by Stephanie C Joachim, Oliver W Gramlich, Panagiotis Laspas, Heiko Schmid, Sabine Beck, Harald D von Pein, H Burkhard Dick, Norbert Pfeiffer, Franz H Grus
Published 2012-01-01

Aged Mice Devoid of the M₃ Muscarinic Acetylcholine Receptor Develop Mild Dry Eye Disease

by Aytan Musayeva, Subao Jiang, Yue Ruan, Jenia Kouchek Zadeh, Panagiotis Chronopoulos, Norbert Pfeiffer, Werner E.G. Müller, Maximilian Ackermann, Ning Xia, Huige Li, Adrian Gericke
Published 2021-06-01

No evidence for an association of plasma homocysteine levels and refractive error - Results from the population-based Gutenberg Health Study (GHS).

by Stefan Nickels, Henk J Blom, Andreas Schulz, Lutz Joachimsen, Thomas Münzel, Philipp S Wild, Manfred E Beutel, Maria Blettner, Karl J Lackner, Norbert Pfeiffer, Wolf A Lagrèze
Published 2020-01-01

Apolipoprotein E Deficiency Causes Endothelial Dysfunction in the Mouse Retina

by Jenia Kouchek Zadeh, Mayagozel B. Zhutdieva, Panagiotis Laspas, Can Yuksel, Aytan Musayeva, Norbert Pfeiffer, Christoph Brochhausen, Matthias Oelze, Andreas Daiber, Ning Xia, Huige Li, Adrian Gericke
Published 2019-01-01

Risk factors, physical and mental health burden of male and female pathological gamblers in the German general population aged 40–80

by Martin Wejbera, Klaus Wölfling, Michael Dreier, Matthias Michal, Elmar Brähler, Jörg Wiltink, Andreas Schulz, Philipp S. Wild, Thomas Münzel, Jochem König, Karl Lackner, Norbert Pfeiffer, Manfred E. Beutel
Published 2021-03-01

Associations between depression and diabetes in the community: do symptom dimensions matter? Results from the Gutenberg Health Study.

by Jörg Wiltink, Matthias Michal, Philipp S Wild, Astrid Schneider, Jochem König, Maria Blettner, Thomas Münzel, Andreas Schulz, Matthias Weber, Christian Fottner, Norbert Pfeiffer, Karl Lackner, Manfred E Beutel
Published 2014-01-01

Distribution of central corneal thickness and its association with ocular parameters in a large central European cohort: the Gutenberg health study.

by Esther M Hoffmann, Julia Lamparter, Alireza Mirshahi, Heike Elflein, René Hoehn, Christian Wolfram, Katrin Lorenz, Max Adler, Philipp S Wild, Andreas Schulz, Barbara Mathes, Maria Blettner, Norbert Pfeiffer
Published 2013-01-01

1.4 Prognostic Relevance of Augmentation Index in Prevalent Cardiovascular Disease and Total Mortality: Data From the General Population

by Natalie Arnold, Tommaso Gori, Anika Gündling, Andreas Schulz, Jürgen H. Prochaska, Marina Panova-Noeva, Irene M. Schmidtmann, Norbert Pfeiffer, Manfred Beutel, Karl J. Lackner, Thomas Münzel, Philipp S Wild
Published 2020-02-01

Relative Telomere Length and Cardiovascular Risk Factors

by Moritz Koriath, Christian Müller, Norbert Pfeiffer, Stefan Nickels, Manfred Beutel, Irene Schmidtmann, Steffen Rapp, Thomas Münzel, Dirk Westermann, Mahir Karakas, Philipp S. Wild, Karl J. Lackner, Stefan Blankenberg, Tanja Zeller
Published 2019-05-01

The National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) – reference data from the German population-based Gutenberg Health Study (GHS)

by Stefan Nickels, Alexander K. Schuster, Susanne Singer, Philipp S. Wild, Dagmar Laubert-Reh, Andreas Schulz, Robert P. Finger, Matthias Michal, Manfred E. Beutel, Thomas Münzel, Karl J. Lackner, Norbert Pfeiffer
Published 2017-08-01

Complaints of sleep disturbances are associated with cardiovascular disease: results from the Gutenberg Health Study.

by Matthias Michal, Jörg Wiltink, Yvonne Kirschner, Astrid Schneider, Philipp S Wild, Thomas Münzel, Maria Blettner, Andreas Schulz, Karl Lackner, Norbert Pfeiffer, Stefan Blankenberg, Regine Tschan, Inka Tuin, Manfred E Beutel
Published 2014-01-01

The association between recalled parental rearing behavior and depressiveness: a comparison between 1st immigrants and non-immigrants in the population-based Gutenberg Health Study

by Eva M. Klein, Elmar Brähler, Katja Petrowski, Ana N. Tibubos, Mareike Ernst, Jörg Wiltink, Matthias Michal, Philipp S. Wild, Andreas Schulz, Thomas Münzel, Jochem König, Karl Lackner, Norbert Pfeiffer, Manfred E. Beutel
Published 2020-07-01

Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort

by Jasmin Rezapour, Alexander K. Schuster, Stefan Nickels, Christina A. Korb, Hisham Elbaz, Tunde Peto, Matthias Michal, Thomas Münzel, Philipp S. Wild, Jochem König, Karl Lackner, Andreas Schulz, Norbert Pfeiffer, Manfred E. Beutel
Published 2020-03-01

Relation between Arterial Stiffness and Markers of Inflammation and Hemostasis – Data from the Population-based Gutenberg Health Study

by Natalie Arnold, Tommaso Gori, Renate B. Schnabel, Andreas Schulz, Jürgen H. Prochaska, Tanja Zeller, Harald Binder, Norbert Pfeiffer, Manfred Beutel, Christine Espinola-Klein, Karl J. Lackner, Stefan Blankenberg, Thomas Münzel, Philipp S. Wild
Published 2017-07-01

Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data.

by Christian Müller, Arne Schillert, Caroline Röthemeier, David-Alexandre Trégouët, Carole Proust, Harald Binder, Norbert Pfeiffer, Manfred Beutel, Karl J Lackner, Renate B Schnabel, Laurence Tiret, Philipp S Wild, Stefan Blankenberg, Tanja Zeller, Andreas Ziegler
Published 2016-01-01

Novel DNA Methylation Sites Influence GPR15 Expression in Relation to Smoking

by Tina Haase, Christian Müller, Julia Krause, Caroline Röthemeier, Justus Stenzig, Sonja Kunze, Melanie Waldenberger, Thomas Münzel, Norbert Pfeiffer, Philipp S. Wild, Matthias Michal, Federico Marini, Mahir Karakas, Karl J. Lackner, Stefan Blankenberg, Tanja Zeller
Published 2018-08-01

Betulinic Acid Protects from Ischemia-Reperfusion Injury in the Mouse Retina

by Aytan Musayeva, Johanna C. Unkrig, Mayagozel B. Zhutdieva, Caroline Manicam, Yue Ruan, Panagiotis Laspas, Panagiotis Chronopoulos, Marie L. Göbel, Norbert Pfeiffer, Christoph Brochhausen, Andreas Daiber, Matthias Oelze, Huige Li, Ning Xia, Adrian Gericke
Published 2021-09-01

First-in-human phase I study of ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta 2 (TGF-β2), in subjects with open-angle glaucoma underg...

by Norbert Pfeiffer, Bogomil Voykov, Giulia Renieri, Katharina Bell, Paul Richter, Melanie Weigel, Hagen Thieme, Barbara Wilhelm, Katrin Lorenz, Martin Feindor, Katja Wosikowski, Michel Janicot, Daniela Päckert, Regina Römmich, Carola Mala, Petra Fettes, Eugen Leo
Published 2017-01-01

Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness.

by Julia Lamparter, Irene Schmidtmann, Alexander K Schuster, Angeliki Siouli, Joanna Wasielica-Poslednik, Alireza Mirshahi, René Höhn, Josef Unterrainer, Philipp S Wild, Harald Binder, Karl Lackner, Manfred E Beutel, Thomas Münzel, Norbert Pfeiffer, Esther M Hoffmann
Published 2018-01-01