Heritable gene editing using FT mobile guide RNAs and DNA viruses

by Jianfeng Lei, Peihong Dai, Yue Li, Wanqi Zhang, Guantong Zhou, Chao Liu, Xiaodong Liu
Published 2021-02-01

Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA

by Pu Gao, Thomas Zillinger, Weiyi Wang, Manuel Ascano, Peihong Dai, Gunther Hartmann, Thomas Tuschl, Liang Deng, Winfried Barchet, Dinshaw J. Patel
Published 2014-09-01

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

by Peihong Dai, Weiyi Wang, Hua Cao, Francesca Avogadri, Lianpan Dai, Ingo Drexler, Johanna A Joyce, Xiao-Dong Li, Zhijian Chen, Taha Merghoub, Stewart Shuman, Liang Deng
Published 2014-04-01

Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain.

by Hua Cao, Peihong Dai, Weiyi Wang, Hao Li, Jianda Yuan, Fangjin Wang, Chee-Mun Fang, Paula M Pitha, Jia Liu, Richard C Condit, Grant McFadden, Taha Merghoub, Alan N Houghton, James W Young, Stewart Shuman, Liang Deng
Published 2012-01-01