Targeting PDGF signaling in carcinoma-associated fibroblasts controls cervical cancer in mouse model.

by Rakesh K Jain, Johanna Lahdenranta, Dai Fukumura
Published 2008-01-01

Neglected giant dermatofibrosarcoma protuberans

by Gautam Prakash, Manojit Midya, Pankaj Sharma, Rakesh K Jain
Published 2019-01-01

Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells.

by Gang Cheng, Janet Tse, Rakesh K Jain, Lance L Munn
Published 2009-01-01

Differential Gene Expression of Primary Cultured Lymphatic and Blood Vascular Endothelial Cells

by Gregory M. Nelson, Timothy P. Padera, Igor Garkavtsev, Toshi Shioda, Rakesh K. Jain
Published 2007-12-01

Conventional and High-Speed Intravital Multiphoton Laser Scanning Microscopy of Microvasculature, Lymphatics, and Leukocyte-Endothelial Interactions

by Timothy P. Padera, Brian R. Stoll, Peter T.C. So, Rakesh K. Jain
Published 2002-01-01

Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases.

by Euiheon Chung, Hiroshi Yamashita, Patrick Au, Bakhos A Tannous, Dai Fukumura, Rakesh K Jain
Published 2009-12-01

VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation.

by Michelle R Dawson, Dan G Duda, Sung-Suk Chae, Dai Fukumura, Rakesh K Jain
Published 2009-09-01

Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells.

by Joshua Tam, Dan G Duda, Jean Y Perentes, Rehan S Quadri, Dai Fukumura, Rakesh K Jain
Published 2009-01-01

Antibody-Directed Effector Cell Therapy of Tumors: Analysis and Optimization Using a Physiologically Based Pharmacokinetic Model

by Stuart W. Friedrich, Stephany C. Linz, Brian R. Stoll, Laurence T. Baxter, Lance L. Munn, Rakesh K. Jain
Published 2002-01-01

Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy

by Claus A. Kristensen, Leena M. Hamberg, George J. Hunter, Sylvie Roberge, Diane Kierstead, Gerald L. Wolf, Rakesh K. Jain
Published 1999-12-01

Systemic Distribution and Tumor Localization of Adoptively Transferred Lymphocytes in Mice: Comparison with Physiologically Based Pharmacokinetic Model

by Robert J. Melder, Lance L. Munn, Brian R. Stoll, Edgardo M. Marecos, Laurence T. Baxter, Ralph Weissleder, Rakesh K. Jain
Published 2002-01-01

PDGF-C induces maturation of blood vessels in a model of glioblastoma and attenuates the response to anti-VEGF treatment.

by Emmanuelle di Tomaso, Nyall London, Daniel Fuja, James Logie, James A Tyrrell, Walid Kamoun, Lance L Munn, Rakesh K Jain
Published 2009-01-01

Merlin/NF2 Regulates Angiogenesis in Schwannomas through a Rac1/Semaphorin 3F-Dependent Mechanism

by Hon-Kit Wong, Akio Shimizu, Nathaniel D. Kirkpatrick, Igor Garkavtsev, Annie W. Chan, Emmanuelle di Tomaso, Michael Klagsbrun, Rakesh K. Jain
Published 2012-02-01

Regorafenib combined with PD1 blockade increases CD8 T-cell infiltration by inducing CXCL10 expression in hepatocellular carcinoma

by Lipika Goyal, Mark Cobbold, Rakesh K Jain, Ivy X Chen, Ayako Shigeta, Daniel Staiculescu, Dieter Zopf, Lukas Fiebig, Gabriela S Hobbs, Peigen Huang
Published 2020-07-01

Correlative intravital imaging of cGMP signals and vasodilation in mice

by Martin eThunemann, Kjestine eSchmidt, Cor eDe Wit, Xiaoxing eHan, Rakesh K Jain, Dai eFukumura, Robert eFeil
Published 2014-10-01

Noninvasive Assessment of Losartan-Induced Increase in Functional Microvasculature and Drug Delivery in Pancreatic Ductal Adenocarcinoma

by Vidhya Kumar, Yves Boucher, Hao Liu, Diego Ferreira, Jacob Hooker, Ciprian Catana, Andrew J. Hoover, Tobias Ritter, Rakesh K. Jain, Alexander R. Guimaraes
Published 2016-10-01

Sensitivity of MRI tumor biomarkers to VEGFR inhibitor therapy in an orthotopic mouse glioma model.

by Christian T Farrar, Walid S Kamoun, Carsten D Ley, Young R Kim, Ciprian Catana, Seon J Kwon, Bruce R Rosen, Rakesh K Jain, A Gregory Sorensen
Published 2011-03-01

Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.

by Joao Incio, Priya Suboj, Shan M Chin, Trupti Vardam-Kaur, Hao Liu, Tai Hato, Suboj Babykutty, Ivy Chen, Vikram Deshpande, Rakesh K Jain, Dai Fukumura
Published 2015-01-01

Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948).

by Chandrajit P Raut, Yves Boucher, Dan G Duda, Jeffrey A Morgan, Richard Quek, Marek Ancukiewicz, Johanna Lahdenranta, J Paul Eder, George D Demetri, Rakesh K Jain
Published 2012-01-01

Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients

by Yves Boucher, Ashwin S. Kumar, Jessica M. Posada, Evisa Gjini, Kathleen Pfaff, Mikel Lipschitz, Ana Lako, Dan G. Duda, Scott J. Rodig, F. Stephen Hodi, Rakesh K. Jain
Published 2021-06-01