Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice

by Abhay P. S. Rathore, Chinmay K. Mantri, Meredith W. Tan, Roksana Shirazi, Andrew Nishida, Siti A. B. Aman, Juliet Morrison, Ashley L. St. John, Ashley L. St. John, Ashley L. St. John
Published 2021-06-01

Submacular integration of hESC-RPE monolayer xenografts in a surgical non-human primate model

by Zengping Liu, Tanja Ilmarinen, Gavin S. W. Tan, Heidi Hongisto, Edmund Y. M. Wong, Andrew S. H. Tsai, Sami Al-Nawaiseh, Graham E. Holder, Xinyi Su, Veluchamy Amutha Barathi, Heli Skottman, Boris V. Stanzel
Published 2021-07-01

Targeted Phenotypic Screening in Plasmodium falciparum and Toxoplasma gondii Reveals Novel Modes of Action of Medicines for Malaria Venture Malaria Box Molecules

by Gowtham Subramanian, Meenakshi A. Belekar, Anurag Shukla, Jie Xin Tong, Ameya Sinha, Trang T. T. Chu, Akshay S. Kulkarni, Peter R. Preiser, D. Srinivasa Reddy, Kevin S. W. Tan, Dhanasekaran Shanmugam, Rajesh Chandramohanadas, William J. Sullivan
Published 2018-01-01

Characterization of the commercially-available fluorescent chloroquine-BODIPY conjugate, LynxTag-CQGREEN, as a marker for chloroquine resistance and uptake in a 96-well plate assay...

by Cheryl C Y Loh, Rossarin Suwanarusk, Yan Quan Lee, Kitti W K Chan, Kit-Ying Choy, Laurent Rénia, Bruce Russell, Martin J Lear, François H Nosten, Kevin S W Tan, Larry M C Chow
Published 2014-01-01

A randomised feasibility trial comparing needle fasciotomy with limited fasciectomy treatment for Dupuytren’s contractures

by T. R. C. Davis, W. Tan, E. F. Harrison, W. Hollingworth, A. Karantana, N. Mills, T. Hepburn, K. Sprange, L. Duley, J. M. Blazeby, C. G. Bainbridge, S. R. Murali, A. A. Montgomery, the HAND-1 Study group
Published 2020-01-01

A Transcriptomic and Epigenomic Comparison of Fetal and Adult Human Cardiac Fibroblasts Reveals Novel Key Transcription Factors in Adult Cardiac Fibroblasts

by Malin K.B. Jonsson, PhD, Robin J.G. Hartman, MSc, Matthew Ackers-Johnson, PhD, Wilson L.W. Tan, BSc, Bing Lim, MD, PhD, Toon A.B. van Veen, PhD, Roger S. Foo, MD
Published 2016-12-01

Generation of HER2-specific antibody immunity during trastuzumab adjuvant therapy associates with reduced relapse in resected HER2 breast cancer

by Nadine Norton, Nicholas Fox, Christie-Ann McCarl, Kathleen S. Tenner, Karla Ballman, Courtney L. Erskine, Brian M. Necela, Donald Northfelt, Winston W. Tan, Carmen Calfa, Mark Pegram, Gerardo Colon-Otero, Edith A. Perez, Raphael Clynes, Keith L. Knutson
Published 2018-06-01

cGMP-grade human iPSC-derived retinal photoreceptor precursor cells rescue cone photoreceptor damage in non-human primates

by Swathi Lingam, Zengping Liu, Binxia Yang, Wendy Wong, Bhav Harshad Parikh, Jun Yi Ong, Debbie Goh, Daniel Soo Lin Wong, Queenie Shu Woon Tan, Gavin S. W. Tan, Graham E. Holder, Kakkad Regha, Veluchamy Amutha Barathi, Walter Hunziker, Gopal Lingam, Xianmin Zeng, Xinyi Su
Published 2021-08-01

Draft genome sequence of the intestinal parasite Blastocystis subtype 4-isolate WR1

by Ivan Wawrzyniak, Damien Courtine, Marwan Osman, Christine Hubans-Pierlot, Amandine Cian, Céline Nourrisson, Magali Chabe, Philippe Poirier, Aldert Bart, Valérie Polonais, Pilar Delgado-Viscogliosi, Hicham El Alaoui, Abdel Belkorchia, Tom van Gool, Kevin S.W. Tan, Stéphanie Ferreira, Eric Viscogliosi, Frédéric Delbac
Published 2015-06-01

Prevalence, Virulence Genes and Antimicrobial Resistance Profiles of Salmonella Serovars from Retail Beef in Selangor, Malaysia

by Tze Y. Thung, Son Radu, Son Radu, Nor A. Mahyudin, Yaya Rukayadi, Zunita Zakaria, Nurzafirah Mazlan, Boon H. Tan, Epeng Lee, Epeng Lee, Soo L. Yeoh, Soo L. Yeoh, Yih Z. Chin, Chia W. Tan, Chee H. Kuan, Dayang F. Basri, Che W. J. Wan Mohamed Radzi
Published 2018-01-01

Prevalence and Antimicrobial Susceptibility of Vibrio parahaemolyticus Isolated from Short Mackerels (Rastrelliger brachysoma) in Malaysia

by Chia W. Tan, Tan T. H. Malcolm, Chee H. Kuan, Tze Y. Thung, Wei S. Chang, Yuet Y. Loo, Jayasekara M. K. J. K. Premarathne, Jayasekara M. K. J. K. Premarathne, Othman B. Ramzi, Mohd F. S. Norshafawatie, Nordin Yusralimuna, Yaya Rukayadi, Yoshitsugu Nakaguchi, Mitsuaki Nishibuchi, Son Radu, Son Radu
Published 2017-06-01

Technical and imaging factors influencing performance of deep learning systems for diabetic retinopathy

by Michelle Y. T. Yip, Gilbert Lim, Zhan Wei Lim, Quang D. Nguyen, Crystal C. Y. Chong, Marco Yu, Valentina Bellemo, Yuchen Xie, Xin Qi Lee, Haslina Hamzah, Jinyi Ho, Tien-En Tan, Charumathi Sabanayagam, Andrzej Grzybowski, Gavin S. W. Tan, Wynne Hsu, Mong Li Lee, Tien Yin Wong, Daniel S. W. Ting
Published 2020-03-01

Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer

by Shamin Li, Yannick Simoni, Etienne Becht, Chiew Yee Loh, Naisi Li, Daniel Lachance, Si-Lin Koo, Teck Por Lim, Emile Kwong Wei Tan, Ronnie Mathew, Andrew Nguyen, Justin Golovato, Julia D. Berkson, Martin Prlic, Bernett Lee, Samuel S. Minot, Niranjan Nagarajan, Neelendu Dey, Daniel S.W. Tan, Iain B. Tan, Evan W. Newell
Published 2020-06-01

Comparing genomic landscape of early stage, treatment naïve and late stage, drug resistant EGFR-mutant lung adenocarcinomas

by Rahul Nahar, Yin Yeng Lee, Alexis J. Khng, Tong Zhang, Angela Takano, Xingliang Liu, Jacob J.S. Alvarez, Ori Zelichov, Ezra Ella, Zohar Barbash, Chong Hee Lim, Tina P.T. Koh, Zaw Win Aung, Tony Kiat Hon Lim, Chee Keong Toh, Wan-Teck Lim, Bing Lim, Wai Leong Tam, Eng-Huat Tan, Weiwei Zhai, Daniel S.W. Tan, Axel M. Hillmer
Published 2017-12-01

Ceritinib Efficacy and Safety in Treatment-Naive Asian Patients With Advanced ALK-Rearranged NSCLC: An ASCEND-4 Subgroup Analysis

by Daniel S.W. Tan, BSc, M.B.B.S., MRCP, PhD, Sarayut Geater, MD, Chong-Jen Yu, MD, PhD, Chun-Ming Tsai, MD, Te-Chun Hsia, MD, Jun Chen, MD, PhD, Meng-Chih Lin, MD, You Lu, MD, Virote Sriuranpong, MD, Cheng-Ta Yang, MD, Paramita Sen, PhD, Fabrice Branle, MD, Michael Shi, MD, Yi-Long Wu, MD
Published 2021-03-01

A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

by Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S. W. Tan, N. Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh
Published 2020-03-01

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

by Shumei Chia, Joo-Leng Low, Xiaoqian Zhang, Xue-Lin Kwang, Fui-Teen Chong, Ankur Sharma, Denis Bertrand, Shen Yon Toh, Hui-Sun Leong, Matan T. Thangavelu, Jacqueline S. G. Hwang, Kok-Hing Lim, Thakshayeni Skanthakumar, Hiang-Khoon Tan, Yan Su, Siang Hui Choo, Hannes Hentze, Iain B. H. Tan, Alexander Lezhava, Patrick Tan, Daniel S. W. Tan, Giridharan Periyasamy, Judice L. Y. Koh, N. Gopalakrishna Iyer, Ramanuj DasGupta
Published 2017-09-01

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing

by Rahul Nahar, Weiwei Zhai, Tong Zhang, Angela Takano, Alexis J. Khng, Yin Yeng Lee, Xingliang Liu, Chong Hee Lim, Tina P. T. Koh, Zaw Win Aung, Tony Kiat Hon Lim, Lavanya Veeravalli, Ju Yuan, Audrey S. M. Teo, Cheryl X. Chan, Huay Mei Poh, Ivan M. L. Chua, Audrey Ann Liew, Dawn Ping Xi Lau, Xue Lin Kwang, Chee Keong Toh, Wan-Teck Lim, Bing Lim, Wai Leong Tam, Eng-Huat Tan, Axel M. Hillmer, Daniel S. W. Tan
Published 2018-01-01

Artificial intelligence using deep learning to screen for referable and vision-threatening diabetic retinopathy in Africa: a clinical validation study

by Valentina Bellemo, MSc, Zhan W Lim, PhD, Gilbert Lim, PhD, Quang D Nguyen, BEng, Yuchen Xie, MScPH, Michelle Y T Yip, BA, Haslina Hamzah, BSc, Jinyi Ho, DFST, Xin Q Lee, BSc (Hons), Wynne Hsu, PhD, Mong L Lee, PhD, Lillian Musonda, MD, Manju Chandran, FRCOphth, Grace Chipalo-Mutati, FCOphth (ECSA), Mulenga Muma, FCOphth (ECSA), Gavin S W Tan, MD, Sobha Sivaprasad, FRCOphth, Geeta Menon, FRCOphth, Tien Y Wong, MD, Daniel S W Ting, MD
Published 2019-05-01

Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages

by Adeline C. Y. Chua, Jessica Jie Ying Ong, Benoit Malleret, Rossarin Suwanarusk, Varakorn Kosaisavee, Anne-Marie Zeeman, Caitlin A. Cooper, Kevin S. W. Tan, Rou Zhang, Bee Huat Tan, Siti Nurdiana Abas, Andy Yip, Anne Elliot, Chester J. Joyner, Jee Sun Cho, Kate Breyer, Szczepan Baran, Amber Lange, Steven P. Maher, François Nosten, Christophe Bodenreider, Bryan K. S. Yeung, Dominique Mazier, Mary R. Galinski, Nathalie Dereuddre-Bosquet, Roger Le Grand, Clemens H. M. Kocken, Laurent Rénia, Dennis E. Kyle, Thierry T. Diagana, Georges Snounou, Bruce Russell, Pablo Bifani
Published 2019-08-01