Erratum: A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma

by Ayelet Gonen, Soo-Ho Choi, Phuong Miu, Colin Agatisa-Boyle, Daniel Acks, Angela M. Taylor, Coleen A. McNamara, Sotirios Tsimikas, Joseph L. Witztum, Yury I. Miller
Published 2019-11-01

A monoclonal antibody to assess oxidized cholesteryl esters associated with apoAI and apoB-100 lipoproteins in human plasma1[S]

by Ayelet Gonen, Soo-Ho Choi, Phuong Miu, Colin Agatisa-Boyle, Daniel Acks, Angela M. Taylor, Coleen A. McNamara, Sotirios Tsimikas, Joseph L. Witztum, Yury I. Miller
Published 2019-02-01

PCSK9 loss-of-function variants and Lp(a) phenotypes among black US adults

by Matthew T. Mefford, Santica M. Marcovina, Vera Bittner, Mary Cushman, Todd M. Brown, Michael E. Farkouh, Sotirios Tsimikas, Keri L. Monda, J. Antonio G. López, Paul Muntner, Robert S. Rosenson
Published 2019-11-01

A novel function of lipoprotein [a] as a preferential carrier of oxidized phospholipids in human plasma

by Claes Bergmark, Asheesh Dewan, Alexina Orsoni, Esther Merki, Elizabeth R. Miller, Min-Jeong Shin, Christoph J. Binder, Sohvi Hörkkö, Ronald M. Krauss, M. John Chapman, Joseph L. Witztum, Sotirios Tsimikas
Published 2008-10-01

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk...

by Amir Ravandi, S. Matthijs Boekholdt, Ziad Mallat, Philippa J. Talmud, John J.P. Kastelein, Nicholas J. Wareham, Elizabeth R. Miller, Joelle Benessiano, Alain Tedgui, Joseph L. Witztum, Kay-Tee Khaw, Sotirios Tsimikas
Published 2011-10-01

Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages.

by Soo-Ho Choi, Huiyong Yin, Amir Ravandi, Aaron Armando, Darren Dumlao, Jungsu Kim, Felicidad Almazan, Angela M Taylor, Coleen A McNamara, Sotirios Tsimikas, Edward A Dennis, Joseph L Witztum, Yury I Miller
Published 2013-01-01

Differential expression of oxidation-specific epitopes and apolipoprotein(a) in progressing and ruptured human coronary and carotid atherosclerotic lesions

by Rogier A. van Dijk, Frank Kolodgie, Amir Ravandi, Gregor Leibundgut, Patrick P. Hu, Anand Prasad, Ehtisham Mahmud, Edward Dennis, Linda K. Curtiss, Joseph L. Witztum, Bruce A. Wasserman, Fumiyuki Otsuka, Renu Virmani, Sotirios Tsimikas
Published 2012-12-01

High-level lipoprotein [a] expression in transgenic mice: evidence for oxidized phospholipids in lipoprotein [a] but not in low density lipoproteins

by Matthias Schneider, Joseph L. Witztum, Stephen G. Young, Erwin H. Ludwig, Elizabeth R. Miller, Sotirios Tsimikas, Linda K. Curtiss, Santica M. Marcovina, John M. Taylor, Richard M. Lawn, Thomas L. Innerarity, Robert E. Pitas
Published 2005-04-01

MCP-1 binds to oxidized LDL and is carried by lipoprotein(a) in human plasma

by Philipp Wiesner, Maria Tafelmeier, Dominik Chittka, Soo-Ho Choi, Li Zhang, Young Sup Byun, Felicidad Almazan, Xiaohong Yang, Navaid Iqbal, Punam Chowdhury, Alan Maisel, Joseph L. Witztum, Tracy M. Handel, Sotirios Tsimikas, Yury I. Miller
Published 2013-07-01

Circulating microparticles carry oxidation-specific epitopes and are recognized by natural IgM antibodies1[S]

by Dimitrios Tsiantoulas, Thomas Perkmann, Taras Afonyushkin, Andreas Mangold, Thomas A. Prohaska, Nikolina Papac-Milicevic, Vincent Millischer, Caroline Bartel, Sohvi Hörkkö, Chantal M. Boulanger, Sotirios Tsimikas, Michael B. Fischer, Joseph L. Witztum, Irene M. Lang, Christoph J. Binder
Published 2015-02-01

Atheroprotective immunization with malondialdehyde-modified LDL is hapten specific and dependent on advanced MDA adducts: implications for development of an atheroprotective vaccin...

by Ayelet Gonen, Lotte F. Hansen, William W. Turner, Erica N. Montano, Xuchu Que, Apaїs Rafia, Meng-Yun Chou, Philipp Wiesner, Dimitrios Tsiantoulas, Maripat Corr, Michael S. VanNieuwenhze, Sotirios Tsimikas, Christoph J. Binder, Joseph L. Witztum, Karsten Hartvigsen
Published 2014-10-01

microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production

by Jianjie Dong, Ming He, Jie Li, Ariane Pessentheiner, Chen Wang, Jin Zhang, Yameng Sun, Wei-Ting Wang, Yuqing Zhang, Junhui Liu, Shen-Chih Wang, Po-Hsun Huang, Philip L.S.M. Gordts, Zu-Yi Yuan, Sotirios Tsimikas, John Y.J. Shyy
Published 2020-12-01

ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance

by Bastian Ramms, Sohan Patel, Chelsea Nora, Ariane R. Pessentheiner, Max W. Chang, Courtney R. Green, Gregory J. Golden, Patrick Secrest, Ronald M. Krauss, Christian M. Metallo, Christopher Benner, Veronica J. Alexander, Joseph L. Witztum, Sotirios Tsimikas, Jeffrey D. Esko, Philip L.S.M. Gordts
Published 2019-08-01

Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data

by Nicholas J. Viney, Shuling Guo, Li‐Jung Tai, Brenda F. Baker, Mariam Aghajan, Shiangtung W. Jung, Rosie Z. Yu, Sheri Booten, Heather Murray, Todd Machemer, Sebastien Burel, Sue Murray, Gustavo Buchele, Sotirios Tsimikas, Eugene Schneider, Richard S. Geary, Merrill D. Benson, Brett P. Monia
Published 2021-02-01

Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

by Michael Torzewski, MD, Amir Ravandi, MD, PhD, Calvin Yeang, MD, PhD, Andrea Edel, PhD, Rahul Bhindi, MD, Stefan Kath, MD, Laura Twardowski, MD, Jens Schmid, PhD, Xiaohong Yang, BS, Ulrich F.W. Franke, MD, Joseph L. Witztum, MD, Sotirios Tsimikas, MD
Published 2017-06-01

Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography

by Audrey-Anne Després, BSc, Nicolas Perrot, MSc, Anthony Poulin, MD, Lionel Tastet, MSc, Mylène Shen, MSc, Hao Yu Chen, MSc, Raphaëlle Bourgeois, MSc, Mikaël Trottier, MD, Michel Tessier, MD, Jean Guimond, MD, Maxime Nadeau, TIM, James C. Engert, PhD, Sébastien Thériault, MD, MSc, Yohan Bossé, PhD, Joseph L. Witztum, MD, Patrick Couture, MD, Patrick Mathieu, MD, MSc, Marc R. Dweck, MD, Sotirios Tsimikas, MD, George Thanassoulis, MD, Philippe Pibarot, PhD, DVM, Marie-Annick Clavel, PhD, DVM, Benoit J. Arsenault, PhD
Published 2019-05-01