Protease Activity of Campylobacter jejuni HtrA Modulates Distinct Intestinal and Systemic Immune Responses in Infected Secondary Abiotic IL-10 Deficient Mice

by Anna-Maria Schmidt, Ulrike Escher, Soraya Mousavi, Manja Boehm, Steffen Backert, Stefan Bereswill, Markus M. Heimesaat
Published 2019-03-01

Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA

by Aileen Harrer, Roland Bücker, Manja Boehm, Urszula Zarzecka, Nicole Tegtmeyer, Heinrich Sticht, Jörg D. Schulzke, Steffen Backert
Published 2019-02-01

Cortactin Is Required for Efficient FAK, Src and Abl Tyrosine Kinase Activation and Phosphorylation of <i>Helicobacter pylori</i> CagA

by Jakob Knorr, Irshad Sharafutdinov, Florian Fiedler, Delara Soltan Esmaeili, Manfred Rohde, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Published 2021-06-01

Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA

by Urszula Zarzecka, Alessandro Grinzato, Eaazhisai Kandiah, Dominik Cysewski, Paola Berto, Joanna Skorko-Glonek, Giuseppe Zanotti, Steffen Backert
Published 2020-11-01

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model

by Anna-Maria Schmidt, Ulrike Escher, Soraya Mousavi, Nicole Tegtmeyer, Manja Boehm, Steffen Backert, Stefan Bereswill, Markus M. Heimesaat
Published 2019-05-01

H. pylori-Induced DNA Strand Breaks Are Introduced by Nucleotide Excision Repair Endonucleases and Promote NF-κB Target Gene Expression

by Mara L. Hartung, Dorothea C. Gruber, Katrin N. Koch, Livia Grüter, Hubert Rehrauer, Nicole Tegtmeyer, Steffen Backert, Anne Müller
Published 2015-10-01

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.

by Xue-Song Zhang, Nicole Tegtmeyer, Leah Traube, Shawn Jindal, Guillermo Perez-Perez, Heinrich Sticht, Steffen Backert, Martin J Blaser
Published 2015-02-01

Differentiation of Gastric <i>Helicobacter</i> Species Using MALDI-TOF Mass Spectrometry

by Helena Berlamont, Chloë De Witte, Sofie De Bruyckere, James G. Fox, Steffen Backert, Annemieke Smet, Filip Boyen, Freddy Haesebrouck
Published 2021-03-01

Peptidase PepP is a novel virulence factor of Campylobacter jejuni contributing to murine campylobacteriosis

by Markus M. Heimesaat, Anna-Maria Schmidt, Soraya Mousavi, Ulrike Escher, Nicole Tegtmeyer, Silja Wessler, Gabriele Gadermaier, Peter Briza, Dirk Hofreuter, Stefan Bereswill, Steffen Backert
Published 2020-11-01

Properties of the HtrA Protease From Bacterium Helicobacter pylori Whose Activity Is Indispensable for Growth Under Stress Conditions

by Urszula Zarzecka, Urszula Zarzecka, Anna Modrak-Wójcik, Donata Figaj, Malgorzata Apanowicz, Adam Lesner, Agnieszka Bzowska, Barbara Lipinska, Anna Zawilak-Pawlik, Steffen Backert, Joanna Skorko-Glonek
Published 2019-05-01

Vitamin D Reverses Disruption of Gut Epithelial Barrier Function Caused by <i>Campylobacter jejuni</i>

by Fábia D. Lobo de Sá, Steffen Backert, Praveen K. Nattramilarasu, Soraya Mousavi, Geoffrey I. Sandle, Stefan Bereswill, Markus M. Heimesaat, Jörg-Dieter Schulzke, Roland Bücker
Published 2021-08-01

Type IV secretion of Helicobacter pylori CagA into oral epithelial cells is prevented by the absence of CEACAM receptor expression

by Nicole Tegtmeyer, Tabita Denisia Ghete, Verena Schmitt, Torsten Remmerbach, Maria Celeste C. Cortes, Edgardo M. Bondoc, Hans-Ludwig Graf, Bernhard B. Singer, Christian Hirsch, Steffen Backert
Published 2020-05-01

Electron microscopic, genetic and protein expression analyses of Helicobacter acinonychis strains from a Bengal tiger.

by Nicole Tegtmeyer, Francisco Rivas Traverso, Manfred Rohde, Omar A Oyarzabal, Norbert Lehn, Wulf Schneider-Brachert, Richard L Ferrero, James G Fox, Douglas E Berg, Steffen Backert
Published 2013-01-01

The <i>Helicobacter pylori</i> Urease Virulence Factor Is Required for the Induction of Hypoxia-Induced Factor-1α in Gastric Cells

by Manuel Valenzuela-Valderrama, Paulina Cerda-Opazo, Steffen Backert, María Fernanda González, Nicolás Carrasco-Véliz, Carla Jorquera-Cordero, Sergio Wehinger, Jimena Canales, Denisse Bravo, Andrew F. G. Quest
Published 2019-06-01

Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adh...

by Hannah M. Hollandsworth, Verena Schmitt, Siamak Amirfakhri, Filemoni Filemoni, Alexej Schmidt, Maréne Landström, Mykola Lyndin, Steffen Backert, Markus Gerhard, Gunther Wennemuth, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet
Published 2020-12-01

T4SS-dependent TLR5 activation by Helicobacter pylori infection

by Suneesh Kumar Pachathundikandi, Nicole Tegtmeyer, Isabelle Catherine Arnold, Judith Lind, Matthias Neddermann, Christina Falkeis-Veits, Sujay Chattopadhyay, Mark Brönstrup, Werner Tegge, Minsun Hong, Heinrich Sticht, Michael Vieth, Anne Müller, Steffen Backert
Published 2019-12-01

Microtubules as platforms for assaying actin polymerization in vivo.

by J Margit Oelkers, Marlene Vinzenz, Maria Nemethova, Sonja Jacob, Frank P L Lai, Jennifer Block, Malgorzata Szczodrak, Eugen Kerkhoff, Steffen Backert, Kai Schlüter, Theresia E B Stradal, J Victor Small, Stefan A Koestler, Klemens Rottner
Published 2011-01-01