Mitochondrial reactive oxygen species and cancer

by Chandel, Navdeep S, Sullivan, Lucas Bryan
Published 2014

Understanding the complex-I-ty of metformin action: limiting mitochondrial respiration to improve cancer therapy

by Luengo, Alba, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
Published 2014

Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin

by Freinkman, Elizaveta, Thomas, Craig J., Gui, Dan Yi, Sullivan, Lucas Bryan, Luengo, Alba, Hosios, Aaron Marc, Bush, Lauren N., Gitego, Nadege, Davidson, Shawn M, Vander Heiden, Matthew G.
Published 2018

Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes

by Kim, Dong-Hwee, Wirtz, Denis, Hecht, Vivian Chaya, Sullivan, Lucas Bryan, Kimmerling, Robert John, Hosios, Aaron Marc, Stockslager, Max Andrew, Stevens, Mark M., Kang, Joon Ho, Vander Heiden, Matthew G., Manalis, Scott R
Published 2016

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection

by Olenchock, Benjamin A, Moslehi, Javid, Baik, Alan H, Williams, Jeremy, Gibson, William J, Chakraborty, Abhishek A, Pierce, Kerry A, Miller, Christine M, Hanse, Eric A, Kelekar, Ameeta, Wagers, Amy J, Clish, Clary B, Kaelin, William G, Davidson, Shawn M, Sullivan, Lucas Bryan, Vander Heiden, Matthew G.
Published 2017

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

by Chan, Sze Ham, Lewis, Caroline, Swier, Lotteke J. Y. M., Chen, Walter W., Sullivan, Lucas Bryan, Fiske, Brian Prescott, Cho, Sung Won, Abu-Remaileh, Monther, Liu, Chieh Ming Jamin, Zhou, Minerva H., Koh, Min Jung, Chung, Haeyoon, Davidson, Shawn M, Luengo, Alba, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward
Published 2017

Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer

by Papagiannakopoulos, Thales, Olenchock, Benjamin A, Heyman, Julia E, Jha, Abhishek K, Pierce, Kerry A, Mott, Bryan T, Clish, Clary B, Davidson, Shawn M., Luengo, Alba, Bauer, Matthew R., Keibler, Mark Andrew, O'Brien, James P., Gui, Dan Yi, Sullivan, Lucas Bryan, Wasylenko, Thomas Michael, Subbaraj, Lakshmipriya, Chin, Christopher R., Stephanopolous, Gregory, Jacks, Tyler E., Vander Heiden, Matthew G.
Published 2018