CDK5 Regulatory Subunit-Associated Protein 1-like 1 Negatively Regulates Adipocyte Differentiation through Activation of Wnt Signaling Pathway

by Kazumi Take, Hironori Waki, Wei Sun, Takahito Wada, Jing Yu, Masahiro Nakamura, Tomohisa Aoyama, Toshimasa Yamauchi, Takashi Kadowaki
Published 2017-08-01

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

by Shinji Furuzono, Tetsuya Kubota, Junki Taura, Masahiro Konishi, Asuka Naito, Masato Tsutsui, Hiroshi Karasawa, Naoto Kubota, Takashi Kadowaki
Published 2021-08-01

Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes

by Jun Hosoe, Ken Suzuki, Fuyuki Miya, Takashi Kato, Tatsuhiko Tsunoda, Yukinori Okada, Momoko Horikoshi, Nobuhiro Shojima, Toshimasa Yamauchi, Takashi Kadowaki
Published 2021-07-01

History of having a macrosomic infant and the risk of diabetes: the Japan public health center-based prospective diabetes study.

by Yusuke Kabeya, Atsushi Goto, Masayuki Kato, Yoshihiko Takahashi, Yumi Matsushita, Manami Inoue, Tetsuya Mizoue, Shoichiro Tsugane, Takashi Kadowaki, Mitsuhiko Noda
Published 2013-01-01

NFIA differentially controls adipogenic and myogenic gene program through distinct pathways to ensure brown and beige adipocyte differentiation.

by Yuta Hiraike, Hironori Waki, Kana Miyake, Takahito Wada, Misato Oguchi, Kaede Saito, Shuichi Tsutsumi, Hiroyuki Aburatani, Toshimasa Yamauchi, Takashi Kadowaki
Published 2020-09-01

Real-world Observational Study on Patient Outcomes in Diabetes (RESPOND): study design and baseline characteristics of patients with type 2 diabetes newly initiating oral antidiabe...

by Daisuke Yabe, Hideki Origasa, Hirotaka Watada, Takashi Kadowaki, Iichiro Shimomura, Hiroko Higashiyama, Keisuke Tobe, Kristy Iglay, Shigeru Tokita, Yutaka Seino
Published 2020-12-01

Factors Associated with Callus Formation in the Plantar Region through Gait Measurement in Patients with Diabetic Neuropathy: An Observational Case-Control Study

by Ayumi Amemiya, Hiroshi Noguchi, Makoto Oe, Kimie Takehara, Yumiko Ohashi, Ryo Suzuki, Toshimasa Yamauchi, Takashi Kadowaki, Hiromi Sanada, Taketoshi Mori
Published 2020-08-01

Role of insulin receptor substrates in the progression of hepatocellular carcinoma

by Yoshitaka Sakurai, Naoto Kubota, Iseki Takamoto, Atsushi Obata, Masahiko Iwamoto, Takanori Hayashi, Masakazu Aihara, Tetsuya Kubota, Hiroshi Nishihara, Takashi Kadowaki
Published 2017-07-01

How self-stigma affects patient activation in persons with type 2 diabetes: a cross-sectional study

by Hideki Hashimoto, Kohjiro Ueki, Toshimasa Yamauchi, Asuka Kato, Yuko Fujimaki, Shin Fujimori, Akihiro Isogawa, Yukiko Onishi, Ryo Suzuki, Takashi Kadowaki
Published 2020-05-01

Shear Stress-Normal Stress (Pressure) Ratio Decides Forming Callus in Patients with Diabetic Neuropathy

by Ayumi Amemiya, Hiroshi Noguchi, Makoto Oe, Kimie Takehara, Yumiko Ohashi, Ryo Suzuki, Toshimasa Yamauchi, Takashi Kadowaki, Hiromi Sanada, Taketoshi Mori
Published 2016-01-01

Impairments in Activities of Daily Living in Older Japanese Men in Hawaii and Japan

by Robert D. Abbott, Aya Kadota, Katsuyuki Miura, Takehito Hayakawa, Takashi Kadowaki, Tomonori Okamura, Akira Okayama, Kamal H. Masaki, Hirotsugu Ueshima
Published 2011-01-01

Factors associated with long-term care certification in older adults: a cross-sectional study based on a nationally representative survey in Japan

by Akira Momose, Satoko Yamaguchi, Akira Okada, Kayo Ikeda-Kurakawa, Daisuke Namiki, Yasuhito Nannya, Hideki Kato, Toshimasa Yamauchi, Masaomi Nangaku, Takashi Kadowaki
Published 2021-06-01

Downregulation of macrophage Irs2 by hyperinsulinemia impairs IL-4-indeuced M2a-subtype macrophage activation in obesity

by Tetsuya Kubota, Mariko Inoue, Naoto Kubota, Iseki Takamoto, Tomoka Mineyama, Kaito Iwayama, Kumpei Tokuyama, Masao Moroi, Kohjiro Ueki, Toshimasa Yamauchi, Takashi Kadowaki
Published 2018-11-01

Pseudo‐hyperglucagonemia was observed in pancreatectomized patients when measured by glucagon sandwich enzyme‐linked immunosorbent assay

by Masaki Kobayashi, Hironori Waki, Hitomi Nakayama, Atsushi Miyachi, Eri Mieno, Hitoshi Hamajima, Moritaka Goto, Kentaro Yamada, Toshimasa Yamauchi, Takashi Kadowaki, Tadahiro Kitamura
Published 2021-02-01

Understanding the experiences of long-term maintenance of self-worth in persons with type 2 diabetes in Japan: a qualitative study

by Yuka Kobayashi, Kazuhiro Yoshiuchi, Toshimasa Yamauchi, Asuka Kato, Yuko Fujimaki, Shin Fujimori, Ryo Suzuki, Takashi Kadowaki, Tomohide Yamada, Masatoshi Kobayashi, Yoshihiko Izumida
Published 2020-08-01

AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice

by Masato Iwabu, Miki Okada-Iwabu, Hiroaki Tanabe, Nozomi Ohuchi, Keiko Miyata, Toshiko Kobori, Sara Odawara, Yuri Kadowaki, Shigeyuki Yokoyama, Toshimasa Yamauchi, Takashi Kadowaki
Published 2021-01-01

Insulin Activates Vagal Afferent Neurons Including those Innervating Pancreas via Insulin Cascade and Ca(2+) Influx: Its Dysfunction in IRS2-KO Mice with Hyperphagic Obesity.

by Yusaku Iwasaki, Kenju Shimomura, Daisuke Kohno, Katsuya Dezaki, Enkh-Amar Ayush, Hajime Nakabayashi, Naoto Kubota, Takashi Kadowaki, Masafumi Kakei, Masanori Nakata, Toshihiko Yada
Published 2013-01-01

Association between nutritional guidance or ophthalmological examination and discontinuation of physician visits in patients with newly diagnosed diabetes: A retrospective cohort s...

by Akira Okada, Sachiko Ono, Satoko Yamaguchi, Hayato Yamana, Kayo Ikeda Kurakawa, Nobuaki Michihata, Hiroki Matsui, Masaomi Nangaku, Toshimasa Yamauchi, Hideo Yasunaga, Takashi Kadowaki
Published 2021-09-01

Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease

by Tomoko Wakabayashi, Kazuki Yamaguchi, Kentaro Matsui, Toshiharu Sano, Tetsuya Kubota, Tadafumi Hashimoto, Ayako Mano, Kaoru Yamada, Yuko Matsuo, Naoto Kubota, Takashi Kadowaki, Takeshi Iwatsubo
Published 2019-04-01

Association between Washing Residue on the Feet and Tinea Pedis in Diabetic Patients

by Kimie Takehara, Ayumi Amemiya, Yuko Mugita, Yuichiro Tsunemi, Yoko Seko, Yumiko Ohashi, Kohjiro Ueki, Takashi Kadowaki, Makoto Oe, Takashi Nagase, Mari Ikeda, Hiromi Sanada
Published 2015-01-01