The effects of a psychological intervention directed at optimizing immune function: study protocol for a randomized controlled trial

by Lemmy Schakel, Dieuwke S. Veldhuijzen, Henriët van Middendorp, Corine Prins, Simone A. Joosten, Tom H. M. Ottenhoff, Leo G. Visser, Andrea W. M. Evers
Published 2017-05-01

Identification of major factors influencing ELISpot-based monitoring of cellular responses to antigens from Mycobacterium tuberculosis.

by Steven G Smith, Simone A Joosten, Virginie Verscheure, Ansar A Pathan, Helen McShane, Tom H M Ottenhoff, Hazel M Dockrell, Françoise Mascart
Published 2009-11-01

Humoral Responses to Rv1733c, Rv0081, Rv1735c, and Rv1737c DosR Regulon-Encoded Proteins of Mycobacterium tuberculosis in Individuals with Latent Tuberculosis Infection

by Simon G. Kimuda, Angela Nalwoga, Jonathan Levin, Kees L. M. C. Franken, Tom H. M. Ottenhoff, Alison M. Elliott, Stephen Cose, Irene Andia-Biraro
Published 2017-01-01

Smoking, BCG and employment and the risk of tuberculosis infection in HIV-infected persons in South Africa.

by Tolu Oni, Hannah P Gideon, Nonzwakazi Bangani, Relebohile Tsekela, Ronnett Seldon, Kathryn Wood, Katalin A Wilkinson, Rene T Goliath, Tom H M Ottenhoff, Robert J Wilkinson
Published 2012-01-01

Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate Improves Host Control of Salmonella enterica Serovar Typhimurium Infection in Human Macrophages

by Cassandra L. R. van Doorn, Gina K. Schouten, Suzanne van Veen, Kimberley V. Walburg, Jeroen J. Esselink, Matthias T. Heemskerk, Frank Vrieling, Tom H. M. Ottenhoff
Published 2021-09-01

HIV-Infected Patients Developing Tuberculosis Disease Show Early Changes in the Immune Response to Novel Mycobacterium tuberculosis Antigens

by Noemi Rebecca Meier, Noemi Rebecca Meier, Manuel Battegay, Manuel Battegay, Tom H. M. Ottenhoff, Hansjakob Furrer, Johannes Nemeth, Nicole Ritz, Nicole Ritz, Nicole Ritz, Nicole Ritz
Published 2021-03-01

Machine Learning Algorithms Evaluate Immune Response to Novel Mycobacterium tuberculosis Antigens for Diagnosis of Tuberculosis

by Noëmi Rebecca Meier, Noëmi Rebecca Meier, Thomas M. Sutter, Marc Jacobsen, Tom H. M. Ottenhoff, Julia E. Vogt, Nicole Ritz, Nicole Ritz, Nicole Ritz, Nicole Ritz
Published 2021-01-01

In-vivo expressed Mycobacterium tuberculosis antigens recognised in three mouse strains after infection and BCG vaccination

by Mariateresa Coppola, Fabienne Jurion, Susan J. F. van den Eeden, Hermann Giresse Tima, Kees L. M. C. Franken, Annemieke Geluk, Marta Romano, Tom H. M. Ottenhoff
Published 2021-06-01

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.

by Simone A Joosten, Krista E van Meijgaarden, Franca Del Nonno, Andrea Baiocchini, Linda Petrone, Valentina Vanini, Hermelijn H Smits, Fabrizio Palmieri, Delia Goletti, Tom H M Ottenhoff
Published 2016-06-01

A high-throughput screen for tuberculosis progression.

by Ralph Carvalho, Jan de Sonneville, Oliver W Stockhammer, Nigel D L Savage, Wouter J Veneman, Tom H M Ottenhoff, Ron P Dirks, Annemarie H Meijer, Herman P Spaink
Published 2011-02-01

Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection.

by Sebastian D Schuck, Henrik Mueller, Frank Kunitz, Albert Neher, Harald Hoffmann, Kees L C M Franken, Dirk Repsilber, Tom H M Ottenhoff, Stefan H E Kaufmann, Marc Jacobsen
Published 2009-01-01

Simultaneous immunization against tuberculosis.

by Elma Z Tchilian, Edward O Ronan, Catherine de Lara, Lian Ni Lee, Kees L M C Franken, Martin H Vordermeier, Tom H M Ottenhoff, Peter C L Beverley
Published 2011-01-01

Biomarkers Can Identify Pulmonary Tuberculosis in HIV-infected Drug Users Months Prior to Clinical Diagnosis

by Rosa Sloot, Maarten F. Schim van der Loeff, Erik W. van Zwet, Mariëlle C. Haks, Sytze T. Keizer, Maarten Scholing, Tom H.M. Ottenhoff, Martien W. Borgdorff, Simone A. Joosten
Published 2015-02-01

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations.

by Willem A Hanekom, Hazel M Dockrell, Tom H M Ottenhoff, T Mark Doherty, Helen Fletcher, Helen McShane, Frank F Weichold, Dan F Hoft, Shreemanta K Parida, Uli J Fruth
Published 2008-07-01

Recombinant ESAT-6-CFP10 Fusion Protein Induction of Th1/Th2 Cytokines and FoxP3 Expressing Treg Cells in Pulmonary TB.

by Dolly Jackson-Sillah, Jacqueline M Cliff, Gloria Ivy Mensah, Emmanuel Dickson, Sandra Sowah, John K A Tetteh, Kwasi K Addo, Tom H M Ottenhoff, Graham Bothamley, Hazel M Dockrell
Published 2013-01-01

Vaccines for Leprosy and Tuberculosis: Opportunities for Shared Research, Development, and Application

by Mariateresa Coppola, Susan J. F. van den Eeden, Naoko Robbins, Louis Wilson, Kees L. M. C. Franken, Linda B. Adams, Tom P. Gillis, Tom H. M. Ottenhoff, Annemieke Geluk
Published 2018-02-01

Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction.

by Rosane M B Teles, Jing Lu, Maria Tió-Coma, Isabela M B Goulart, Sayera Banu, Deanna Hagge, Kidist Bobosha, Tom H M Ottenhoff, Matteo Pellegrini, Annemieke Geluk, Robert L Modlin
Published 2019-10-01

Host Blood RNA Transcript and Protein Signatures for Sputum-Independent Diagnostics of Tuberculosis in Adults

by Dhanasekaran Sivakumaran, Dhanasekaran Sivakumaran, Christian Ritz, Christian Ritz, John Espen Gjøen, Mario Vaz, Sumithra Selvam, Tom H. M. Ottenhoff, Timothy Mark Doherty, Synne Jenum, Harleen M. S. Grewal, Harleen M. S. Grewal
Published 2021-02-01

Higher frequency of T-cell response to M. tuberculosis latency antigen Rv2628 at the site of active tuberculosis disease than in peripheral blood.

by Teresa Chiacchio, Elisa Petruccioli, Valentina Vanini, Ornella Butera, Gilda Cuzzi, Linda Petrone, Giuseppe Matteucci, Francesco Nicola Lauria, Kees L M C Franken, Enrico Girardi, Tom H M Ottenhoff, Delia Goletti
Published 2011-01-01

Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?

by Jonathan W. Uzorka, Lucia J.M. Kroft, Jaap A. Bakker, Erik W. van Zwet, Erik Huisman, Corine Prins, Cornelis J. van der Zwan, Tom H.M. Ottenhoff, Sandra M. Arend
Published 2019-05-01