Both Hypoxia-Inducible Factor 1 and MAPK Signaling Pathway Attenuate PI3K/AKT via Suppression of Reactive Oxygen Species in Human Pluripotent Stem Cells

by Petr Fojtík, Petr Fojtík, Deborah Beckerová, Deborah Beckerová, Katerina Holomková, Martin Šenfluk, Martin Šenfluk, Vladimir Rotrekl, Vladimir Rotrekl
Published 2021-01-01

AFM Monitoring the Influence of Selected Cryoprotectants on Regeneration of Cryopreserved Cells Mechanical Properties

by Martin Golan, Sarka Jelinkova, Sarka Jelinkova, Irena Kratochvílová, Petr Skládal, Martin Pešl, Martin Pešl, Martin Pešl, Vladimír Rotrekl, Vladimír Rotrekl, Jan Pribyl
Published 2018-06-01

Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic Tools

by Ivana Acimovic, Aleksandra Vilotic, Martin Pesl, Alain Lacampagne, Petr Dvorak, Vladimir Rotrekl, Albano C. Meli
Published 2014-01-01

Cardiovascular progenitor cells and tissue plasticity are reduced in a myocardium affected by Becker muscular dystrophy

by Martin Pesl, Sarka Jelinkova, Guido Caluori, Maria Holicka, Jan Krejci, Petr Nemec, Aneta Kohutova, Vita Zampachova, Petr Dvorak, Vladimir Rotrekl
Published 2020-03-01

AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study

by Guido Caluori, Guido Caluori, Guido Caluori, Eva Odehnalova, Tomasz Jadczyk, Tomasz Jadczyk, Martin Pesl, Martin Pesl, Martin Pesl, Iveta Pavlova, Lucia Valikova, Steffen Holzinger, Veronika Novotna, Veronika Novotna, Vladimir Rotrekl, Vladimir Rotrekl, Ales Hampl, Ales Hampl, Michal Crha, Dalibor Cervinka, Zdenek Starek, Zdenek Starek
Published 2020-12-01

Generation of two Duchenne muscular dystrophy patient-specific induced pluripotent stem cell lines DMD02 and DMD03 (MUNIi001-A and MUNIi003-A)

by Sarka Jelinkova, Lenka Markova, Martin Pesl, Iveta Valáškova, Eva Makaturová, Lenka Jurikova, Petr Vondracek, Alain Lacampagne, Petr Dvorak, Albano C. Meli, Vladimir Rotrekl
Published 2019-10-01

DMD Pluripotent Stem Cell Derived Cardiac Cells Recapitulate in vitro Human Cardiac Pathophysiology

by Sarka Jelinkova, Sarka Jelinkova, Aleksandra Vilotic, Jan Pribyl, Franck Aimond, Anton Salykin, Ivana Acimovic, Martin Pesl, Martin Pesl, Martin Pesl, Guido Caluori, Guido Caluori, Simon Klimovic, Tomas Urban, Hana Dobrovolna, Vladimir Soska, Vladimir Soska, Petr Skladal, Petr Skladal, Alain Lacampagne, Petr Dvorak, Petr Dvorak, Albano C. Meli, Albano C. Meli, Vladimir Rotrekl, Vladimir Rotrekl
Published 2020-06-01

Oxygen Is an Ambivalent Factor for the Differentiation of Human Pluripotent Stem Cells in Cardiac 2D Monolayer and 3D Cardiac Spheroids

by Monia Souidi, Yvonne Sleiman, Ivana Acimovic, Jan Pribyl, Azzouz Charrabi, Volker Baecker, Valerie Scheuermann, Martin Pesl, Sarka Jelinkova, Petr Skladal, Petr Dvorak, Alain Lacampagne, Vladimir Rotrekl, Albano C. Meli
Published 2021-01-01

Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress

by Sarka Jelinkova, Petr Fojtik, Aneta Kohutova, Aleksandra Vilotic, Lenka Marková, Martin Pesl, Tereza Jurakova, Miriama Kruta, Jan Vrbsky, Renata Gaillyova, Iveta Valášková, Ivan Frák, Alain Lacampagne, Giancarlo Forte, Petr Dvorak, Albano C. Meli, Vladimir Rotrekl
Published 2019-01-01

Dystrophin Deficiency Causes Progressive Depletion of Cardiovascular Progenitor Cells in the Heart

by Sarka Jelinkova, Yvonne Sleiman, Petr Fojtík, Franck Aimond, Amanda Finan, Gerald Hugon, Valerie Scheuermann, Deborah Beckerová, Olivier Cazorla, Marie Vincenti, Pascal Amedro, Sylvain Richard, Josef Jaros, Petr Dvorak, Alain Lacampagne, Gilles Carnac, Vladimir Rotrekl, Albano C. Meli
Published 2021-05-01

Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds

by Veronika Palušová, Tereza Renzová, Amandine Verlande, Tereza Vaclová, Michaela Medková, Linda Cetlová, Miroslava Sedláčková, Hana Hříbková, Iva Slaninová, Miriama Krutá, Vladimír Rotrekl, Hana Uhlířová, Aneta Křížová, Radim Chmelík, Pavel Veselý, Michaela Krafčíková, Lukáš Trantírek, Kay Oliver Schink, Stjepan Uldrijan
Published 2020-06-01

Post-Translational Modifications and Diastolic Calcium Leak Associated to the Novel RyR2-D3638A Mutation Lead to CPVT in Patient-Specific hiPSC-Derived Cardiomyocytes

by Ivana Acimovic, Marwan M. Refaat, Adrien Moreau, Anton Salykin, Steve Reiken, Yvonne Sleiman, Monia Souidi, Jan Přibyl, Andrey V. Kajava, Sylvain Richard, Jonathan T. Lu, Philippe Chevalier, Petr Skládal, Petr Dvořak, Vladimir Rotrekl, Andrew R. Marks, Melvin M. Scheinman, Alain Lacampagne, Albano C. Meli
Published 2018-11-01