Safety and efficacy of azacitidine in myelodysplastic syndromes

by Carlos E Vigil, Taida Martin-Santos, Guillermo Garcia-Manero
Published 2010-09-01

Epigenetic therapy in allogeneic hematopoietic stem cell transplantation

by Qaiser Bashir, Basem Magdy William, Guillermo Garcia-Manero, Marcos de Lima
Published 2013-01-01

Acute myeloid leukemia: current progress and future directions

by Hagop Kantarjian, Tapan Kadia, Courtney DiNardo, Naval Daver, Gautam Borthakur, Elias Jabbour, Guillermo Garcia-Manero, Marina Konopleva, Farhad Ravandi
Published 2021-02-01

Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis

by Xin You, Weiye Jiang, Wenhua Lu, Hui Zhang, Tiantian Yu, Jingyu Tian, Shijun Wen, Guillermo Garcia-Manero, Peng Huang, Yumin Hu
Published 2019-04-01

Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest.

by Irene Gañán-Gómez, Yue Wei, Hui Yang, Sherry Pierce, Carlos Bueso-Ramos, George Calin, María Del Carmen Boyano-Adánez, Guillermo García-Manero
Published 2014-01-01

Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia.

by Shao-Qing Kuang, Zhihong Fang, Patrick A Zweidler-McKay, Hui Yang, Yue Wei, Emilio A Gonzalez-Cervantes, Yanis Boumber, Guillermo Garcia-Manero
Published 2013-01-01

Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies.

by Eric Laille, Tao Shi, Guillermo Garcia-Manero, Christopher R Cogle, Steven D Gore, Joel Hetzer, Keshava Kumar, Barry Skikne, Kyle J MacBeth
Published 2015-01-01

Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States

by Iman Abou Dalle, Hagop Kantarjian, Jan Burger, Zeev Estrov, Maro Ohanian, Srdan Verstovsek, Farhad Ravandi, Gautam Borthakur, Guillermo Garcia‐Manero, Elias Jabbour, Jorge Cortes
Published 2019-11-01

Phase II, Open Label, Randomized Comparative Trial of Ondansetron Alone versus the Combination of Ondansetron and Aprepitant for the Prevention of Nausea and Vomiting in Patients w...

by Talha Badar, Jorge Cortes, Gautam Borthakur, Susan O’Brien, William Wierda, Guillermo Garcia-Manero, Alessandra Ferrajoli, Tapan Kadia, Rebeca Poku, Hagop Kantarjian, Gloria Mattiuzzi
Published 2015-01-01

HDAC inhibitors repress BARD1 isoform expression in acute myeloid leukemia cells via activation of miR-19a and/or b.

by Ilaria Lepore, Carmela Dell'Aversana, Maxim Pilyugin, Mariarosaria Conte, Angela Nebbioso, Floriana De Bellis, Francesco P Tambaro, Tiziana Izzo, Guillermo Garcia-Manero, Felicetto Ferrara, Irmgard Irminger-Finger, Lucia Altucci
Published 2013-01-01

Overexpression of the toll-like receptor (TLR) signaling adaptor MYD88, but lack of genetic mutation, in myelodysplastic syndromes.

by Sophie Dimicoli, Yue Wei, Carlos Bueso-Ramos, Hui Yang, Courtney Dinardo, Yu Jia, Hong Zheng, Zhihong Fang, Martin Nguyen, Sherry Pierce, Rui Chen, Hui Wang, Chenghua Wu, Guillermo Garcia-Manero
Published 2013-01-01

Validation of International Working Group response criteria in higher‐risk myelodysplastic syndromes: A report on behalf of the MDS Clinical Research Consortium

by Rami S. Komrokji, Najla H Al Ali, David Sallman, Eric Padron, Amy E. DeZern, John Barnard, Gail J. Roboz, Guillermo Garcia‐Manero, Alan List, David P. Steensma, Mikkael A. Sekeres
Published 2021-01-01

Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes

by Hussein A. Abbas, Patrick K. Reville, Xianli Jiang, Hui Yang, Alexandre Reuben, Jin Seon Im, Jin Seon Im, Latasha Little, Jefferson C. Sinson, Ken Chen, Andrew Futreal, Andrew Futreal, Guillermo Garcia-Manero
Published 2021-04-01

MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy

by Stefan Heinrichs, Lillian F Conover, Carlos E Bueso-Ramos, Outi Kilpivaara, Kristen Stevenson, Donna Neuberg, Mignon L Loh, Wen-Shu Wu, Scott J Rodig, Guillermo Garcia-Manero, Hagop M Kantarjian, A Thomas Look
Published 2013-07-01

Immunotherapy in Acute Myeloid Leukemia: Where We Stand

by Alessandro Isidori, Claudio Cerchione, Naval Daver, Courtney DiNardo, Guillermo Garcia-Manero, Marina Konopleva, Elias Jabbour, Farhad Ravandi, Tapan Kadia, Adolfo de la Fuente Burguera, Alessandra Romano, Federica Loscocco, Giuseppe Visani, Giovanni Martinelli, Hagop Kantarjian, Antonio Curti
Published 2021-05-01

Tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia: a single-institution experience

by Kamal Chamoun, Hagop Kantarjian, Rami Atallah, Graciela Nogueras Gonzalez, Ghayas C. Issa, Mary Beth Rios, Guillermo Garcia-Manero, Gautam Borthakur, Farhad Ravandi, Nitin Jain, Naval Daver, Marina Konopleva, Courtney D. DiNardo, Tapan Kadia, Naveen Pemmaraju, Elias Jabbour, Jorge Cortes
Published 2019-01-01

Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements

by Ghayas C. Issa, Jabra Zarka, Koji Sasaki, Wei Qiao, Daewoo Pak, Jing Ning, Nicholas J. Short, Fadi Haddad, Zhenya Tang, Keyur P. Patel, Branko Cuglievan, Naval Daver, Courtney D. DiNardo, Elias Jabbour, Tapan Kadia, Gautam Borthakur, Guillermo Garcia-Manero, Marina Konopleva, Michael Andreeff, Hagop M. Kantarjian, Farhad Ravandi
Published 2021-09-01

744 Single cell profiling of acute myeloid leukemia (AML) and its microenvironment reveals a CD8 continuum and adaptable T cell plasticity in response to PD-1 blockade-based therap...

by Feng Wang, Wei Wang, Michael Green, Ruiping Wang, Jianhua Zhang, Andrew Futreal, Jing Ning, James Allison, Padmanee Sharma, Marina Konopleva, Latasha Little, Hussein Abbas, Katarzyna Tomczak, Praveen Barrodia, Jin Seon Im, Patrick Reville, Zoe Alaniz, Gheath Al-Atrash, Koichi Takahashi, Maomao Ding, Jairo Matthews, Sreyashi Basu, Guillermo Garcia-Manero, Steven Kornblau, Kunal Rai, Naval Daver
Published 2020-11-01

Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications

by Sang T. Kim, Ajay Sheshadri, Vickie Shannon, Dimitrios P. Kontoyiannis, Hagop Kantarjian, Guillermo Garcia-Manero, Farhad Ravandi, Jin S. Im, Prajwal Boddu, Lara Bashoura, Diwakar D. Balachandran, Scott E. Evans, Saadia Faiz, Wilfredo Ruiz Vazquez, Margarita Divenko, Rohit Mathur, Samantha P. Tippen, Curtis Gumbs, Sattva S. Neelapu, Aung Naing, Linghua Wang, Adi Diab, Andrew Futreal, Roza Nurieva, Naval Daver
Published 2021-01-01

Post-transplantation cyclophosphamide reduces the incidence of acute graft-versus-host disease in patients with acute myeloid leukemia/myelodysplastic syndromes who receive immune...

by Maro Ohanian, Farhad Ravandi, Maria E Suarez-Almazor, Noha Abdel-Wahab, Houssein Safa, Ala Abudayyeh, Stephen Gruschkus, May Daher, Richard Champlin, Kaysia Ludford, Guillermo Garcia-Manero, Hind Rafei, Jacinth Joseph, Gabriela Rondon, Laura Whited, Faisal Fa'ak, Cristina Knape, Mahran Shoukier, Megan Marcotulli, Alison M Gulbis, Betul Oran, Uday R Popat, Rotesh Mehta, Amin M Alousi
Published 2021-02-01