VASCULAR CALCIFICATION: FROM INNOCENT BYSTANDER TO CULPRIT RISK FACTOR

by Leon J. Schurgers
Published 2017-12-01

New Insights into the Pros and Cons of the Clinical Use of Vitamin K Antagonists (VKAs) Versus Direct Oral Anticoagulants (DOACs)

by Rick H. van Gorp, Leon J. Schurgers
Published 2015-11-01

Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells

by Asim Cengiz Akbulut, Grzegorz B. Wasilewski, Grzegorz B. Wasilewski, Nikolas Rapp, Francesco Forin, Heike Singer, Katrin J. Czogalla-Nitsche, Leon J. Schurgers, Leon J. Schurgers
Published 2021-01-01

Inflammation and Microcalcification are Processes That May be Non-Invasively Identified Via Molecular Imaging as Markers for Vulnerable Plaques

by Alexandru Florea, Agnieszka Morgenroth, Jan Bucerius, Leon J. Schurgers, Felix M. Mottaghy
Published 2020-01-01

The Bone—Vasculature Axis: Calcium Supplementation and the Role of Vitamin K

by Grzegorz B. Wasilewski, Grzegorz B. Wasilewski, Marc G. Vervloet, Leon J. Schurgers
Published 2019-02-01

Pharmacological and Nutritional Modulation of Vascular Calcification

by Liv M. Vossen, Abraham A. Kroon, Leon J. Schurgers, Peter W. de Leeuw
Published 2019-12-01

Missense mutation of VKORC1 leads to medial arterial calcification in rats

by Arnaud Michaux, Benjamin Matagrin, Jean-Valéry Debaux, Leon J. Schurgers, Etienne Benoit, Virginie Lattard
Published 2018-09-01

Decreased Levels of Circulating Carboxylated Osteocalcin in Children with Low Energy Fractures: A Pilot Study

by Janusz Popko, Michał Karpiński, Sylwia Chojnowska, Katarzyna Maresz, Robert Milewski, Vladimir Badmaev, Leon J. Schurgers
Published 2018-06-01

Effects of Combined Vitamin K2 and Vitamin D3 Supplementation on Na[¹⁸F]F PET/MRI in Patients with Carotid Artery Disease: The INTRICATE Rationale and Trial Design

by Alexandru Florea, M. Eline Kooi, Werner Mess, Leon J. Schurgers, Jan Bucerius, Felix M. Mottaghy
Published 2021-03-01

Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles

by Leon J. Schurgers, Asim C. Akbulut, Dawid M. Kaczor, Maurice Halder, Rory R. Koenen, Rafael Kramann
Published 2018-04-01

Vitamin K Antagonist Use and Risk for Intracranial Carotid Artery Calcification in Patients With Intracerebral Hemorrhage

by Michaël T. J. Peeters, Rik Houben, Alida A. Postma, Robert J. van Oostenbrugge, Leon J. Schurgers, Julie Staals
Published 2019-12-01

Mechanisms of arterial remodeling: lessons from genetic diseases

by Bernard eVan Varik, Roger eRennenberg, Chris eReutelingsperger, Abraham eKroon, Peter ede Leeuw, Leon J Schurgers
Published 2012-12-01

High-Dose Menaquinone-7 Supplementation Reduces Cardiovascular Calcification in a Murine Model of Extraosseous Calcification

by Daniel Scheiber, Verena Veulemans, Patrick Horn, Martijn L. Chatrou, Sebastian A. Potthoff, Malte Kelm, Leon J. Schurgers, Ralf Westenfeld
Published 2015-08-01

Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug–Bug Interaction?

by Lu Dai, Björn K. Meijers, Bert Bammens, Henriette de Loor, Leon J. Schurgers, Abdul Rashid Qureshi, Peter Stenvinkel, Pieter Evenepoel
Published 2020-05-01

Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging

by Geert Hendrikx, Tilman M. Hackeng, Rick van Gorp, Matthias Bauwens, Leon J. Schurgers, Felix M. Mottaghy, Mark J. Post, Ingrid Dijkgraaf
Published 2017-01-01

The role of kidney transplantation and phosphate binder use in vitamin K status.

by Thijs T Jansz, Aegida Neradova, Adriana J van Ballegooijen, Marianne C Verhaar, Marc G Vervloet, Leon J Schurgers, Brigit C van Jaarsveld
Published 2018-01-01

Novel effects of diets enriched with corn oil or with an olive oil/sunflower oil mixture on vitamin K metabolism and vitamin K-dependent proteins in young men

by Leon J. Schurgers, Martin J. Shearer, Berry A.M. Soute, Ibrahim Elmadfa, Julia Harvey, Karl-Heinz Wagner, Richard Tomasch, Cees Vermeer
Published 2002-06-01

Sodium [¹⁸F]Fluoride PET Can Efficiently Monitor In Vivo Atherosclerotic Plaque Calcification Progression and Treatment

by Alexandru Florea, Julius P. Sigl, Agnieszka Morgenroth, Andreas Vogg, Sabri Sahnoun, Oliver H. Winz, Jan Bucerius, Leon J. Schurgers, Felix M. Mottaghy
Published 2021-01-01

Intra-Section Analysis of Human Coronary Arteries Reveals a Potential Role for Micro-Calcifications in Macrophage Recruitment in the Early Stage of Atherosclerosis.

by Martijn L L Chatrou, Jack P Cleutjens, Ger J van der Vusse, Ruben B Roijers, Peter H A Mutsaers, Leon J Schurgers
Published 2015-01-01

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

by Lu Dai, Oscar Plunde, Abdul Rashid Qureshi, Bengt Lindholm, Torkel B. Brismar, Leon J. Schurgers, Magnus Söderberg, Jonaz Ripsweden, Magnus Bäck, Peter Stenvinkel
Published 2020-02-01