Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response.

by Andrew A Beharry, Zachary D Nagel, Leona D Samson, Eric T Kool
Published 2016-01-01

Alkylation induced cerebellar degeneration dependent on Aag and Parp1 does not occur via previously established cell death mechanisms.

by Carrie M Margulies, Isaac Alexander Chaim, Aprotim Mazumder, June Criscione, Leona D Samson
Published 2017-01-01

Identification of novel human damage response proteins targeted through yeast orthology.

by J Peter Svensson, Rebecca C Fry, Emma Wang, Luis A Somoza, Leona D Samson
Published 2012-01-01

Microcolony Size Distribution Assay Enables High-Throughput Cell Survival Quantitation

by Le P. Ngo, Tze Khee Chan, Jing Ge, Leona D. Samson, Bevin P. Engelward
Published 2019-02-01

Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae.

by Rachel L Erlich, Rebecca C Fry, Thomas J Begley, Danielle L Daee, Robert S Lahue, Leona D Samson
Published 2008-01-01

Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids i...

by J Peter Svensson, Laia Quirós Pesudo, Siobhan K McRee, Yeyejide Adeleye, Paul Carmichael, Leona D Samson
Published 2013-01-01

Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.

by Ivan Rusyn, Rebecca C Fry, Thomas J Begley, Joanna Klapacz, J Peter Svensson, Mark Ambrose, Leona D Samson
Published 2007-11-01

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells.

by Zachary D Nagel, Andrew A Beharry, Patrizia Mazzucato, Gaspar J Kitange, Jann N Sarkaria, Eric T Kool, Leona D Samson
Published 2019-01-01

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts.

by Elena K Braithwaite, Padmini S Kedar, Deborah J Stumpo, Barbara Bertocci, Jonathan H Freedman, Leona D Samson, Samuel H Wilson
Published 2010-08-01

Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.

by Jennifer A Calvo, Catherine A Moroski-Erkul, Annabelle Lake, Lindsey W Eichinger, Dharini Shah, Iny Jhun, Prajit Limsirichai, Roderick T Bronson, David C Christiani, Lisiane B Meira, Leona D Samson
Published 2013-04-01

Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers.

by Rebecca C Fry, Panida Navasumrit, Chandni Valiathan, J Peter Svensson, Bradley J Hogan, Manlin Luo, Sanchita Bhattacharya, Krittinee Kandjanapa, Sumitra Soontararuks, Sumontha Nookabkaew, Chulabhorn Mahidol, Mathuros Ruchirawat, Leona D Samson
Published 2007-11-01

Correction to: Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

by Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Chalida Chompoobut, Ta Thi Binh, Doan Ngoc Hai, Nguyen Duy Bao, Nguyen Khac Hai, Kyoung-Woong Kim, Leona D. Samson, Joseph H. Graziano, Chulabhorn Mahidol, Mathuros Ruchirawat
Published 2019-07-01

Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study

by Panida Navasumrit, Krittinee Chaisatra, Jeerawan Promvijit, Varabhorn Parnlob, Somchamai Waraprasit, Chalida Chompoobut, Ta Thi Binh, Doan Ngoc Hai, Nguyen Duy Bao, Nguyen Khac Hai, Kyoung-Woong Kim, Leona D. Samson, Joseph H. Graziano, Chulabhorn Mahidol, Mathuros Ruchirawat
Published 2019-06-01

Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression

by Nicola P. Montaldo, Diana L. Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L. Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C. Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D. Samson, Barbara van Loon
Published 2019-11-01

The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.

by Glen E Kisby, Rebecca C Fry, Michael R Lasarev, Theodor K Bammler, Richard P Beyer, Mona Churchwell, Daniel R Doerge, Lisiane B Meira, Valerie S Palmer, Ana-Luiza Ramos-Crawford, Xuefeng Ren, Robert C Sullivan, Terrance J Kavanagh, Leona D Samson, Helmut Zarbl, Peter S Spencer
Published 2011-01-01

DNA alkylation repair deficient mice are susceptible to chemically induced Inflammatory Bowel Disease

by Green, Stephanie Lauren
Published 2006

Functional DNA repair capacity assays : a focus on base excision repair

by Chaim, Isaac Alexander
Published 2016

Anc1 : a new player in the cellular response to DNA damage

by Erlich, Rachel L
Published 2008

Alkyladenine DNA glycosylase (Aag)-dependent cell-specific responses to alkylating agents

by Margulies, Carrie Marie
Published 2016

Understanding cell fate decisions in response to 0⁶-Methylguanine DNA lesions

by Noonan, Ericka Marie
Published 2013