Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology

by Raquel Vivet-Noguer, Malcy Tarin, Sergio Roman-Roman, Samar Alsafadi
Published 2019-07-01

Using First-Passage Times to Analyze Tumor Growth Delay

by Patricia Román-Román, Sergio Román-Román, Juan José Serrano-Pérez, Francisco Torres-Ruiz
Published 2021-03-01

Functional and conformational impact of cancer-associated SF3B1 mutations depends on the position and the charge of amino acid substitution

by Christine Canbezdi, Malcy Tarin, Alexandre Houy, Dorine Bellanger, Tatiana Popova, Marc-Henri Stern, Sergio Roman-Roman, Samar Alsafadi
Published 2021-01-01

AXL Controls Directed Migration of Mesenchymal Triple-Negative Breast Cancer Cells

by Olivier Zajac, Renaud Leclere, André Nicolas, Didier Meseure, Caterina Marchiò, Anne Vincent-Salomon, Sergio Roman-Roman, Marie Schoumacher, Thierry Dubois
Published 2020-01-01

Transcriptome analysis of Wnt3a-treated triple-negative breast cancer cells.

by Sylvie Maubant, Bruno Tesson, Virginie Maire, Mengliang Ye, Guillem Rigaill, David Gentien, Francisco Cruzalegui, Gordon C Tucker, Sergio Roman-Roman, Thierry Dubois
Published 2015-01-01

Spontaneous mouse lymphoma in patient-derived tumor xenografts: The importance of systematic analysis of xenografted human tumor tissues in preclinical efficacy trials

by Sophie Chateau-Joubert, Miriam Hopfe, Sophie Richon, Didier Decaudin, Sergio Roman-Roman, Edouard Reyes-Gomez, Ivan Bieche, Fariba Nemati, Virginie Dangles-Marie
Published 2021-08-01

Prognostic Implications of MRI Melanin Quantification and Cytogenetic Abnormalities in Liver Metastases of Uveal Melanoma

by Toulsie Ramtohul, Khadija Ait Rais, Sophie Gardrat, Raymond Barnhill, Sergio Román-Román, Nathalie Cassoux, Manuel Rodrigues, Pascale Mariani, Leanne De Koning, Gaëlle Pierron, Vincent Servois
Published 2021-05-01

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

by Samar Alsafadi, Alexandre Houy, Aude Battistella, Tatiana Popova, Michel Wassef, Emilie Henry, Franck Tirode, Angelos Constantinou, Sophie Piperno-Neumann, Sergio Roman-Roman, Martin Dutertre, Marc-Henri Stern
Published 2016-02-01

Definition of Biologically Distinct Groups of Conjunctival Melanomas According to Etiological Factors and Implications for Precision Medicine

by Sophie Gardrat, Alexandre Houy, Kelly Brooks, Nathalie Cassoux, Raymond Barnhill, Stéphane Dayot, Ivan Bièche, Virginie Raynal, Sylvain Baulande, Richard Marais, Sergio Roman-Roman, Marc-Henri Stern, Manuel Rodrigues
Published 2021-07-01

Ultraviolet radiation drives mutations in a subset of mucosal melanomas

by Piyushkumar A. Mundra, Nathalie Dhomen, Manuel Rodrigues, Lauge Hjorth Mikkelsen, Nathalie Cassoux, Kelly Brooks, Sara Valpione, Jorge S. Reis-Filho, Steffen Heegaard, Marc-Henri Stern, Sergio Roman-Roman, Richard Marais
Published 2021-01-01

Protein arginine methyltransferase 5: A novel therapeutic target for triple‐negative breast cancers

by Mathilde Vinet, Samyuktha Suresh, Virginie Maire, Clarisse Monchecourt, Fariba Némati, Laetitia Lesage, Fabienne Pierre, Mengliang Ye, Auriane Lescure, Amélie Brisson, Didier Meseure, André Nicolas, Guillem Rigaill, Elisabetta Marangoni, Elaine Del Nery, Sergio Roman‐Roman, Thierry Dubois
Published 2019-05-01

Replacement and desmoplastic histopathological growth patterns in cutaneous melanoma liver metastases: frequency, characteristics, and robust prognostic value

by Raymond Barnhill, Pieter‐Jan vanDam, Peter Vermeulen, Gabriel Champenois, André Nicolas, Robert V Rawson, James S Wilmott, John F Thompson, Georgina V Long, Nathalie Cassoux, Sergio Roman‐Roman, Klaus J Busam, Richard A Scolyer, Alexander J Lazar, Claire Lugassy
Published 2020-07-01

Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenografts.

by Ludmilla de Plater, Anne Vincent-Salomon, Frédérique Berger, André Nicolas, Sophie Vacher, Eléonore Gravier, Aurélie Thuleau, Narjesse Karboul, Marion Richardson, Clément Elbaz, Elisabetta Marangoni, Ivan Bièche, Xavier Paoletti, Sergio Roman-Roman, Patricia A Culp, Bernard Asselain, Véronique Diéras, Didier Decaudin
Published 2014-01-01

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer.

by Virginie Maire, Céline Baldeyron, Marion Richardson, Bruno Tesson, Anne Vincent-Salomon, Eléonore Gravier, Bérengère Marty-Prouvost, Leanne De Koning, Guillem Rigaill, Aurélie Dumont, David Gentien, Emmanuel Barillot, Sergio Roman-Roman, Stéphane Depil, Francisco Cruzalegui, Alain Pierré, Gordon C Tucker, Thierry Dubois
Published 2013-01-01

The Expression of Anti-Müllerian Hormone Type II Receptor (AMHRII) in Non-Gynecological Solid Tumors Offers Potential for Broad Therapeutic Intervention in Cancer

by Jean-Marc Barret, André Nicolas, Anne Jarry, Olivier Dubreuil, Didier Meseure, Tilda Passat, Emeline Perrial, Cécile Deleine, Gabriel Champenois, Solenne Gaillard, Emilie Duchalais, Isabelle Ray-Coquard, Mehdi Lahmar, Charles Dumontet, Jaafar Bennouna, Céline Bossard, Sergio Roman-Roman, Jean-François Prost
Published 2021-04-01

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization.

by David Vallerand, Gérald Massonnet, Fatima Kébir, David Gentien, Zofia Maciorowski, Pierre De la Grange, Brigitte Sigal-Zafrani, Marion Richardson, Sandrine Humbert, Aurélie Thuleau, Franck Assayag, Ludmilla de Plater, André Nicolas, Suzy Scholl, Elisabetta Marangoni, Stefan Weigand, Sergio Roman-Roman, Ariel Savina, Didier Decaudin
Published 2016-01-01

Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences

by Wulfran Cacheux, Petros Tsantoulis, Adrien Briaux, Sophie Vacher, Pascale Mariani, Marion Richard‐Molard, Bruno Buecher, Sophie Richon, Emmanuelle Jeannot, Julien Lazartigues, Etienne Rouleau, Odette Mariani, Elsy El Alam, Jérôme Cros, Sergio Roman‐Roman, Emmanuel Mitry, Elodie Girard, Virginie Dangles‐Marie, Astrid Lièvre, Ivan Bièche
Published 2018-07-01

PARP Inhibition Increases the Response to Chemotherapy in Uveal Melanoma

by Leanne de Koning, Didier Decaudin, Rania El Botty, André Nicolas, Guillaume Carita, Mathieu Schuller, Bérengère Ouine, Aurélie Cartier, Adnan Naguez, Justine Fleury, Vesselina Cooke, Andrew Wylie, Paul Smith, Elisabetta Marangoni, David Gentien, Didier Meseure, Pascale Mariani, Nathalie Cassoux, Sophie Piperno-Neumann, Sergio Roman-Roman, Fariba Némati
Published 2019-05-01

High-Throughput Drug Screening Identifies Pazopanib and Clofilium Tosylate as Promising Treatments for Malignant Rhabdoid Tumors

by Céline Chauvin, Amaury Leruste, Arnault Tauziede-Espariat, Mamy Andrianteranagna, Didier Surdez, Aurianne Lescure, Zhi-Yan Han, Elodie Anthony, Wilfrid Richer, Sylvain Baulande, Mylène Bohec, Sakina Zaidi, Marie-Ming Aynaud, Laetitia Maillot, Julien Masliah-Planchon, Stefano Cairo, Sergio Roman-Roman, Olivier Delattre, Elaine Del Nery, Franck Bourdeaut
Published 2017-11-01

So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020

by Manuel Rodrigues, Leanne de Koning, Sarah E. Coupland, Aart G. Jochemsen, Richard Marais, Marc-Henri Stern, André Valente, Raymond Barnhill, Nathalie Cassoux, Andrew Evans, Iain Galloway, Martine J. Jager, Ellen Kapiteijn, Bozena Romanowska-Dixon, Bettina Ryll, Sergio Roman-Roman, Sophie Piperno-Neumann, the UM Cure 2020 Consortium
Published 2019-07-01