Autoimmune responses in the rheumatoid synovium.

by Rene E M Toes, Tom W J Huizinga
Published 2009-01-01

Tweaking microtubules to treat scleroderma.

by Jacob M van Laar, Tom W J Huizinga
Published 2005-12-01

How to prevent, minimize, or extinguish nocebo effects in pain: a narrative review on mechanisms, predictors, and interventions

by Meriem Manaï, Henriët van Middendorp, Dieuwke S. Veldhuijzen, Tom W.J. Huizinga, Andrea W.M. Evers
Published 2019-06-01

Enhanced treatment strategies and distinct disease outcomes among autoantibody-positive and -negative rheumatoid arthritis patients over 25 years: A longitudinal cohort study in th...

by Xanthe M E Matthijssen, Ellis Niemantsverdriet, Tom W J Huizinga, Annette H M van der Helm-van Mil
Published 2020-09-01

Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the art...

by Bastiaan T. van Dijk, Leendert A. Trouw, Annette H. M. van der Helm-van Mil, Tom W. J. Huizinga
Published 2020-04-01

Selective involvement of the amygdala in systemic lupus erythematosus.

by Bart J Emmer, Jeroen van der Grond, Gerda M Steup-Beekman, Tom W J Huizinga, Mark A van Buchem
Published 2006-12-01

Association between several clinical and radiological determinants with long-term clinical progression and good prognosis of lower limb osteoarthritis.

by Erlangga Yusuf, Jessica Bijsterbosch, P Eline Slagboom, Herman M Kroon, Frits R Rosendaal, Tom W J Huizinga, Margreet Kloppenburg
Published 2011-01-01

Pharmacological conditioning in the treatment of recent-onset rheumatoid arthritis: a randomized controlled trial study protocol

by Meriem Manaï, Henriët van Middendorp, Dieuwke S. Veldhuijzen, Joy A. van der Pol, Tom W. J. Huizinga, Andrea W. M. Evers
Published 2020-01-01

ACPA-negative RA consists of subgroups: patients with high likelihood of achieving sustained DMARD-free remission can be identified by serological markers at disease presentation

by Debbie M. Boeters, Leonie E. Burgers, Eric H. Sasso, Tom W. J. Huizinga, Annette H. M. van der Helm – van Mil
Published 2019-05-01

Body mass index and treatment survival in patients with RA starting treatment with TNFα-inhibitors: long-term follow-up in the real-life METEOR registry

by Cornelia F Allaart, Tom W J Huizinga, Sytske Anne Bergstra, Elizabeth Murphy, Karen Salomon Escoto, David Vega-Morales, Marieke De Buck
Published 2020-08-01

Similar short-term clinical response to high-dose versus low-dose methotrexate in monotherapy and combination therapy in patients with rheumatoid arthritis

by Sytske Anne Bergstra, Cornelia F. Allaart, Rosaline van den Berg, Arvind Chopra, Nimmisha Govind, Tom W. J. Huizinga, Robert B. M. Landewe
Published 2017-11-01

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis.

by Jeroen N Stoop, Bi-Sheng Liu, Jing Shi, Diahann T S L Jansen, Martin Hegen, Tom W J Huizinga, Leendert A Trouw, René E M Toes
Published 2014-01-01

A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren’s Syndrome and Alters Receptor Expression as well as Functional Response

by Bekir Karakaya, Coline H. M. van Moorsel, Marcel Veltkamp, Claudia Roodenburg-Benschop, Karin M. Kazemier, Annette H. M. van der Helm-van Mil, Tom W. J. Huizinga, Jan C. Grutters, Ger T. Rijkers
Published 2021-08-01

Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis.

by Linda M Slot, Rochelle D Vergroesen, Priscilla F Kerkman, Ellen Staudinger, Sanne Reijm, Hugo J van Dooren, Ellen I H van der Voort, Tom W J Huizinga, René E M Toes, Hans U Scherer
Published 2021-01-01

Circulating calprotectin (S100A8/A9) is higher in rheumatoid arthritis patients that relapse within 12 months of tapering anti-rheumatic drugs

by Emma C. de Moel, Jürgen Rech, Michael Mahler, Johannes Roth, Thomas Vogl, Anne Schouffoer, Robbert J. Goekoop, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Georg Schett, Diane van der Woude
Published 2019-12-01

Profiling the secretion of soluble mediators by end stage osteoarthritis synovial tissue explants reveals a reduced responsiveness to an inflammatory trigger.

by Lobke M Gierman, Benno van El, Frits van der Ham, Angela Koudijs, Reinout Stoop, Jan H Verheijen, Margreet Kloppenburg, Gerjo J V M van Osch, Vedrana Stojanovic-Susulic, Tom W J Huizinga, Anne-Marie Zuurmond
Published 2013-01-01

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

by Emma C. de Moel, Veerle F. A. M. Derksen, Leendert A. Trouw, Holger Bang, Gerard Collée, Leroy R. Lard, Sofia Ramiro, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
Published 2019-01-01

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

by Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude
Published 2018-02-01

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

by Debbie M. Boeters, Lukas Mangnus, Sofia Ajeganova, Elisabet Lindqvist, Björn Svensson, René E. M. Toes, Leendert A. Trouw, Tom W. J. Huizinga, Francis Berenbaum, Jacques Morel, Solbritt Rantapää-Dahlqvist, Annette H. M. van der Helm-van Mil
Published 2017-05-01

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

by Myrthe A. M. van Delft, Marije K. Verheul, Leonie E. Burgers, Veerle F. A. M. Derksen, Annette H. M. van der Helm-van Mil, Diane van der Woude, Tom W. J. Huizinga, René E. M. Toes, Leendert A. Trouw
Published 2017-08-01