Ubiquitin and Autophagy

• Format: eBook
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Biology, life sciences; Research & information: general; aggrephagy; APP; ATG12~5/16 complex; Atg8; autophagy; autophagy initiation; autophagy-lysosome pathway; BECN1; C. elegans; cargo receptors; crosstalk; Cx43; degradation; Dictyostelium; endosome; ER-phagy; FIP200; GABARAP; gap junction; globoid cell leukodystrophy; islet; LC3; leukodystrophies; lipophagy; LIR motif; lysophagy; lysosome; MAPLC3; mitophagy; n/a; neurodegenerative diseases; NFAT5; nucleophagy; p62; phagocytosis; pinocytosis; plants; proteasome; PSMD14; psychosine; retrograde; retromer; SAR; selective autophagy; sorting nexins; the ubiquitin-proteasome system; tissue specificity; toll-like receptor 4; TRAF6; trafficking; ubiquitin; ubiquitin-like protein; ubiquitin-proteasome system; ubiquitination; UBL; unfolded protein response; UPR; UPS; xenophagy
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication

 This book is a collection of articles from the Cells Special Issue on "Ubiquitin and Autophagy". It contains an Editorial and 13 articles at the intersection of ubiquitin- and autophagy-related processes. Ubiquitin is a small protein modifier that is widely used to tag proteins, organelles, and pathogens for their degradation by the ubiquitin-proteasome system and/or autophagy-lysosomal pathway. Interestingly, several ubiquitin-like proteins are at a core of the autophagy mechanism. This book dedicates a lot of attention to the crosstalk between the ubiquitin-proteasome system and autophagy and serves as a good starting point for the readers interested in the current state of the knowledge on ubiquitin and autophagy.