Relapsing (recurrent) disease caused by Borrelia miyamotoi
Aim. To clarify the clinical, laboratory, and epidemiological characteristics of relapsing Ixodes tick-borne borreliosis (ITB) caused by Borrelia miyamotoi. Subjects and methods. Retrospective clinical observation was made in 79 inpatients of the Republican Infectious Diseases Hospital (Udmurt Repub...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | Russian |
Published: |
"Consilium Medicum" Publishing house
2015-11-01
|
Series: | Терапевтический архив |
Subjects: | |
Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31843 |
id |
doaj-002839792bf74171ac88f4202febf972 |
---|---|
record_format |
Article |
spelling |
doaj-002839792bf74171ac88f4202febf9722020-11-25T03:04:45Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422015-11-018711182528859Relapsing (recurrent) disease caused by Borrelia miyamotoiD S SarksyanV V MaleevA E PlatonovO V PlatonovaL S KaranAim. To clarify the clinical, laboratory, and epidemiological characteristics of relapsing Ixodes tick-borne borreliosis (ITB) caused by Borrelia miyamotoi. Subjects and methods. Retrospective clinical observation was made in 79 inpatients of the Republican Infectious Diseases Hospital (Udmurt Republic), who had been diagnosed with B. miyamotoi-caused disease verified by real-time polymerase chain reaction. The latter and enzyme immunoassay ruled out possible vector-borne coinfections (ITB caused by B. burgdorferi sensu lato; tick-borne encephalitis; anaplasmosis; and ehrlichiosis). Results. The recurrent course of the disease was observed in 8 (10%) of the 79 patients. The relapsing fever curve was noted in 6 of the 8 patients; 4 patients had 2 episodes of fever and 2 patients had 3 episodes; the wave-like continuous type of fever cannot enable one to estimate the specific number of episodes in 2 more cases. Relapses occurred in all the 8 patients before antibiotic treatment. Febrile syndrome (weakness, headache, chill, fever, sweating, dizziness, nausea, vomiting, myalgia, and arthralgia) was leading in patients with relapses. These patients were less frequently observed to have signs of organ dysfunctions than those with one episode of fever. The values of clinical and biochemical blood tests and urinalyses were normal and near-normal in the majority of patients on hospital admission. Conclusion. Relapsing B. miyamotoi infection cases detected in the directed study proved to be unrecognized by practical health authorities during the first and sometimes second episodes of fever. This indicates that the prevalence of this disease is essentially underestimated and there is a need to increase physicians’ alertness and awareness and to introduce adequate diagnostic methods.https://ter-arkhiv.ru/0040-3660/article/view/31843borrelia miyamotoiixodes tick-borne borreliosisrelapsing feverudmurtia |
collection |
DOAJ |
language |
Russian |
format |
Article |
sources |
DOAJ |
author |
D S Sarksyan V V Maleev A E Platonov O V Platonova L S Karan |
spellingShingle |
D S Sarksyan V V Maleev A E Platonov O V Platonova L S Karan Relapsing (recurrent) disease caused by Borrelia miyamotoi Терапевтический архив borrelia miyamotoi ixodes tick-borne borreliosis relapsing fever udmurtia |
author_facet |
D S Sarksyan V V Maleev A E Platonov O V Platonova L S Karan |
author_sort |
D S Sarksyan |
title |
Relapsing (recurrent) disease caused by Borrelia miyamotoi |
title_short |
Relapsing (recurrent) disease caused by Borrelia miyamotoi |
title_full |
Relapsing (recurrent) disease caused by Borrelia miyamotoi |
title_fullStr |
Relapsing (recurrent) disease caused by Borrelia miyamotoi |
title_full_unstemmed |
Relapsing (recurrent) disease caused by Borrelia miyamotoi |
title_sort |
relapsing (recurrent) disease caused by borrelia miyamotoi |
publisher |
"Consilium Medicum" Publishing house |
series |
Терапевтический архив |
issn |
0040-3660 2309-5342 |
publishDate |
2015-11-01 |
description |
Aim. To clarify the clinical, laboratory, and epidemiological characteristics of relapsing Ixodes tick-borne borreliosis (ITB) caused by Borrelia miyamotoi. Subjects and methods. Retrospective clinical observation was made in 79 inpatients of the Republican Infectious Diseases Hospital (Udmurt Republic), who had been diagnosed with B. miyamotoi-caused disease verified by real-time polymerase chain reaction. The latter and enzyme immunoassay ruled out possible vector-borne coinfections (ITB caused by B. burgdorferi sensu lato; tick-borne encephalitis; anaplasmosis; and ehrlichiosis). Results. The recurrent course of the disease was observed in 8 (10%) of the 79 patients. The relapsing fever curve was noted in 6 of the 8 patients; 4 patients had 2 episodes of fever and 2 patients had 3 episodes; the wave-like continuous type of fever cannot enable one to estimate the specific number of episodes in 2 more cases. Relapses occurred in all the 8 patients before antibiotic treatment. Febrile syndrome (weakness, headache, chill, fever, sweating, dizziness, nausea, vomiting, myalgia, and arthralgia) was leading in patients with relapses. These patients were less frequently observed to have signs of organ dysfunctions than those with one episode of fever. The values of clinical and biochemical blood tests and urinalyses were normal and near-normal in the majority of patients on hospital admission. Conclusion. Relapsing B. miyamotoi infection cases detected in the directed study proved to be unrecognized by practical health authorities during the first and sometimes second episodes of fever. This indicates that the prevalence of this disease is essentially underestimated and there is a need to increase physicians’ alertness and awareness and to introduce adequate diagnostic methods. |
topic |
borrelia miyamotoi ixodes tick-borne borreliosis relapsing fever udmurtia |
url |
https://ter-arkhiv.ru/0040-3660/article/view/31843 |
work_keys_str_mv |
AT dssarksyan relapsingrecurrentdiseasecausedbyborreliamiyamotoi AT vvmaleev relapsingrecurrentdiseasecausedbyborreliamiyamotoi AT aeplatonov relapsingrecurrentdiseasecausedbyborreliamiyamotoi AT ovplatonova relapsingrecurrentdiseasecausedbyborreliamiyamotoi AT lskaran relapsingrecurrentdiseasecausedbyborreliamiyamotoi |
_version_ |
1724680011048288256 |