Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway

Dexmedetomidine Inhibits Inflammatory Reaction in Lung Tissues of Septic Rats by Suppressing TLR4/NF-κB Pathway

Dexmedetomidine has been reported to reduce mortality in septic rats. This study was designed to investigate the effects of dexmedetomidine on inflammatory reaction in lung tissues of septic rats induced by CLP. After induction of sepsis, the rats were treated with normal saline or dexmedetomidine...

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Bibliographic Details
Main Authors:	Yuqing Wu, Yingchun Liu, He Huang, Yangzi Zhu, Yong Zhang, Fuzhao Lu, Ce Zhou, Li Huang, Xin Li, Chenghua Zhou
Format:	Article
Language:	English
Published:	Hindawi Limited 2013-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2013/562154

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