Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial

Background and Aims: Early psychomotor recovery is an essential part of day care surgery which depends on brain integration of motor and sensory co-ordination. Even though dexmedetomidine is commonly used for day care procedures, the recovery profile was not studied. Hence, this study was designed t...

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Main Authors: Tilak Perika, Suman Lata Gupta, Lenin Babu Elakkumanan, Shivanand Kattimani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2019;volume=35;issue=2;spage=236;epage=241;aulast=Perika
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spelling doaj-0030b93d460d4640a3ee81ce21b763822020-11-25T00:16:19ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852019-01-0135223624110.4103/joacp.JOACP_390_17Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trialTilak PerikaSuman Lata GuptaLenin Babu ElakkumananShivanand KattimaniBackground and Aims: Early psychomotor recovery is an essential part of day care surgery which depends on brain integration of motor and sensory co-ordination. Even though dexmedetomidine is commonly used for day care procedures, the recovery profile was not studied. Hence, this study was designed to evaluate the psychomotor recovery of sedation with dexmedetomidine during spinal anesthesia. Material and Methods: Sixty-six patients were included. Group D received dexmedetomidine 0.5 μg/kg (loading dose) followed by 0.2–1 μg/kg/hour. Group P received propofol infusion of 25–100 μg/kg/minute. Psychomotor recovery was assessed by finger-tapping, manual dexterity, visual spatial memory capacity, and pen and paper tests. Psychomotor tasks were given to the patients postoperatively at every 30 minutes for 2 hours followed by every hour up to 4 hours after surgery. Distribution of patients, age, weight, duration of surgery, and the level of sensory blockade was compared using independent t-test. Student's t-test has been used to find the significance of parameters such as heart rate, mean arterial pressure, oxygen saturation (SpO2), psychomotor recovery between two groups. P < 0.05 was considered as significant. Results: The motor recovery using finger tapping test was faster in Group D than Group P (73.94 ± 42.13 vs 101.21 ± 37.98 minutes, P–value = 0.007). Motor recovery using peg board test was faster in Group P than Group D (82.12 ± 40.37 vs 99.39 ± 43.08 minutes, P–value = 0.098). Visual spatial capacity memory test and pen and paper test were unaffected. Conclusions: We conclude that patients who received dexmedetomidine showed earlier recovery with finger tapping test. Hence, we suggest to use dexmedetomidine for complete psychomotor recovery and fast-track discharging of the patient after spinal anesthesia.http://www.joacp.org/article.asp?issn=0970-9185;year=2019;volume=35;issue=2;spage=236;epage=241;aulast=PerikaDexmedetomidinefinger tapping testpeg board testpen and paper testpropofolpsychomotor recoveryvisual spatial capacity test
collection DOAJ
language English
format Article
sources DOAJ
author Tilak Perika
Suman Lata Gupta
Lenin Babu Elakkumanan
Shivanand Kattimani
spellingShingle Tilak Perika
Suman Lata Gupta
Lenin Babu Elakkumanan
Shivanand Kattimani
Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
Journal of Anaesthesiology Clinical Pharmacology
Dexmedetomidine
finger tapping test
peg board test
pen and paper test
propofol
psychomotor recovery
visual spatial capacity test
author_facet Tilak Perika
Suman Lata Gupta
Lenin Babu Elakkumanan
Shivanand Kattimani
author_sort Tilak Perika
title Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
title_short Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
title_full Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
title_fullStr Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
title_full_unstemmed Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
title_sort psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: a randomized control trial
publisher Wolters Kluwer Medknow Publications
series Journal of Anaesthesiology Clinical Pharmacology
issn 0970-9185
publishDate 2019-01-01
description Background and Aims: Early psychomotor recovery is an essential part of day care surgery which depends on brain integration of motor and sensory co-ordination. Even though dexmedetomidine is commonly used for day care procedures, the recovery profile was not studied. Hence, this study was designed to evaluate the psychomotor recovery of sedation with dexmedetomidine during spinal anesthesia. Material and Methods: Sixty-six patients were included. Group D received dexmedetomidine 0.5 μg/kg (loading dose) followed by 0.2–1 μg/kg/hour. Group P received propofol infusion of 25–100 μg/kg/minute. Psychomotor recovery was assessed by finger-tapping, manual dexterity, visual spatial memory capacity, and pen and paper tests. Psychomotor tasks were given to the patients postoperatively at every 30 minutes for 2 hours followed by every hour up to 4 hours after surgery. Distribution of patients, age, weight, duration of surgery, and the level of sensory blockade was compared using independent t-test. Student's t-test has been used to find the significance of parameters such as heart rate, mean arterial pressure, oxygen saturation (SpO2), psychomotor recovery between two groups. P < 0.05 was considered as significant. Results: The motor recovery using finger tapping test was faster in Group D than Group P (73.94 ± 42.13 vs 101.21 ± 37.98 minutes, P–value = 0.007). Motor recovery using peg board test was faster in Group P than Group D (82.12 ± 40.37 vs 99.39 ± 43.08 minutes, P–value = 0.098). Visual spatial capacity memory test and pen and paper test were unaffected. Conclusions: We conclude that patients who received dexmedetomidine showed earlier recovery with finger tapping test. Hence, we suggest to use dexmedetomidine for complete psychomotor recovery and fast-track discharging of the patient after spinal anesthesia.
topic Dexmedetomidine
finger tapping test
peg board test
pen and paper test
propofol
psychomotor recovery
visual spatial capacity test
url http://www.joacp.org/article.asp?issn=0970-9185;year=2019;volume=35;issue=2;spage=236;epage=241;aulast=Perika
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AT leninbabuelakkumanan psychomotorrecoveryofdexmedetomidinecomparedwithpropofolaftersedationduringspinalanesthesiaarandomizedcontroltrial
AT shivanandkattimani psychomotorrecoveryofdexmedetomidinecomparedwithpropofolaftersedationduringspinalanesthesiaarandomizedcontroltrial
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