Analysis of Cellular Heterogeneity in Immune Microenvironment of Primary Central Nervous System Lymphoma by Single-Cell Sequencing

Analysis of Cellular Heterogeneity in Immune Microenvironment of Primary Central Nervous System Lymphoma by Single-Cell Sequencing

BackgroundPrimary central nervous system lymphoma (PCNSL) is characterized by a lack of specificity and poor prognosis. Further understanding of the tumor heterogeneity and molecular phenotype of PCNSL is of great significance for improving the diagnosis and treatment of this disease.MethodsTo explo...

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Bibliographic Details
Main Authors: Boyuan Wei, Zhe Liu, Yue Fan, Shuwei Wang, Chao Dong, Wei Rao, Fan Yang, Gang Cheng, Jianning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Oncology
Subjects:
primary central nervous system lymphoma (PCNSL)
single cell sequencing
cellular heterogeneity
immune microenvironment
pathogenic and therapeutic
cell communication
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.683007/full

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