Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?

Pseudoxanthoma elasticum and nephrocalcinosis: Incidental finding or an infrequent manifestation?

Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopatho...

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Bibliographic Details
Main Authors: Tirthankar Gayen, Anupam Das, Sudipta Roy, Shamick Biswas, Kaushik Shome, Satyendra N Chowdhury
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Dermatology Online Journal
Subjects:
Association
nephrocalcinosis
pseudoxanthoma elasticum
Online Access:http://www.idoj.in/article.asp?issn=2229-5178;year=2014;volume=5;issue=2;spage=176;epage=178;aulast=Gayen
Description
Summary:Pseudoxanthoma elasticum (PXE) is an inherited disorder characterized by generalized fragmentation and progressive calcification of elastic tissue. We report two sporadic cases of PXE, both of whom presented with asymptomatic yellowish papules over the flexural sites for cosmetic reasons. Histopathological findings on hematoxylin and eosin and Verhoeff-Van Gieson (VVG) staining were classical of PXE. In addition to this, renal calcification was documented on plain radiography of kidneys, ureters, and bladder (KUB) in both the cases. Paucity of literature describing the association of nephrocalcinosis with PXE prompted the present report.
ISSN:2229-5178

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