Impact of mcr-1 on the Development of High Level Colistin Resistance in Klebsiella pneumoniae and Escherichia coli

Impact of mcr-1 on the Development of High Level Colistin Resistance in Klebsiella pneumoniae and Escherichia coli

Plasmid-mediated colistin resistance gene mcr-1 generally confers low-level resistance. The purpose of this study was to investigate the impact of mcr-1 on the development of high-level colistin resistance (HLCR) in Klebsiella pneumoniae and Escherichia coli. In this study, mcr-1-negative K. pneumon...

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Bibliographic Details
Main Authors: Xiao-Qing Zhu, Yi-Yun Liu, Renjie Wu, Haoliang Xun, Jian Sun, Jian Li, Yaoyu Feng, Jian-Hua Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
mcr-1
Enterobacterales
colistin
resistance
fitness cost
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.666782/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.666782/full

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