Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer’s disease and type 2 diabetes

Empagliflozin reduces vascular damage and cognitive impairment in a mixed murine model of Alzheimer’s disease and type 2 diabetes

Abstract Background Both Alzheimer’s disease (AD) and type 2 diabetes (T2D) share common pathological features including inflammation, insulin signaling alterations, or vascular damage. AD has no successful treatment, and the close relationship between both diseases supports the study of antidiabeti...

Full description

Bibliographic Details
Main Authors: Carmen Hierro-Bujalance, Carmen Infante-Garcia, Angel del Marco, Marta Herrera, Maria Jose Carranza-Naval, Javier Suarez, Pilar Alves-Martinez, Simon Lubian-Lopez, Monica Garcia-Alloza
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Type 2 diabetes
Amyloid-β
Hemorrhage
Microglia
Tau
Online Access:http://link.springer.com/article/10.1186/s13195-020-00607-4

Internet

http://link.springer.com/article/10.1186/s13195-020-00607-4

Similar Items