| Summary: | The neurosurgeons of PLA General Hospital are making effort to participate in the China Brain Project from the aspects of Science, Technology, Engineering and Medicine, namely "STEM". We initiated the brain research by utilizing central nervous system tumor and other brain diseases as unique study models, and leveraging specific technologies such as neuroimaging, intraoperative electrical stimulation and intracranial electroencephalography. Moreover, we further combine engineering advances with brain⁃inspired intelligence as well as novel materials to develop minimally invasive or non⁃invasive brain⁃computer interface (BCI) devices. With the aim of diagnosis and intervention of Alzheimer's disease (AD) and other major brain diseases, we have used physical neuromodulation (such as sound, light, electricity, magnetism, etc.) for therapeutic treatments of these brain disorders, so as to contribute to the brain research and clinical translation in China in a significant way.
DOI：10.3969/j.issn.1672⁃6731.2019.12.002
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