A Comprehensive Understanding of Choroidal Metastasis from Lung Cancer

Zihan Qu,* Jiewei Liu,* Lingling Zhu, Qinghua Zhou Lung Cancer Center, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Zhou 610041 Tel +1-5715238138Email prof...

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Bibliographic Details
Main Authors: Qu Z, Liu J, Zhu L, Zhou Q
Format: Article
Language:English
Published: Dove Medical Press 2021-08-01
Series:OncoTargets and Therapy
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Online Access:https://www.dovepress.com/a-comprehensive-understanding-of-choroidal-metastasis-from-lung-cancer-peer-reviewed-fulltext-article-OTT
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Summary:Zihan Qu,* Jiewei Liu,* Lingling Zhu, Qinghua Zhou Lung Cancer Center, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qinghua Zhou 610041 Tel +1-5715238138Email prof_qh_zhou@126.comAbstract: The incidence of lung cancer with intraocular metastasis is low, of which choroidal metastasis is the most painful metastatic lesion. The clinical symptoms resulting from choroidal metastasis from lung cancer easily detected although they are rarely identified prior to the diagnosis of the primary malignancy. The quality of life of patients is inevitably impaired. Some lung cancer patients complain of ocular symptoms as the first manifestation of lung cancer. Early diagnosis and treatment can significantly overcome or delay the visual impairment and improve prognosis. The main therapeutic modalities include systemic and local treatments, while observation is also a treatment option. Currently, the feasibility and effectiveness of various treatment options are controversial worldwide. Herein, we summarize the underlying mechanisms, epidemiology, clinical features, auxiliary examinations, diagnosis, and recent treatment options for intraocular metastases.Keywords: intraocular tumor, cancer therapeutics, systemic therapy, local therapy
ISSN:1178-6930