STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.

STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.

The JAK/STAT signaling pathway is suggested to play an important role in the pathogenesis of psoriasis, and recently JAK/STAT inhibitors have shown promising results in psoriasis treatment. The present study aimed to characterize the role of STAT2 in psoriasis. We demonstrated an increased expressio...

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Bibliographic Details
Main Authors: Claus Johansen, Anne Hald Rittig, Maike Mose, Trine Bertelsen, Isabella Weimar, Jakob Nielsen, Thomas Andersen, Tue Kruse Rasmussen, Bent Deleuran, Lars Iversen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5417613?pdf=render

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