Chemical proteasome inhibition as a novel animal model of inner retinal degeneration in rats.
Chemical proteasome inhibition has been a valuable animal model of neurodegeneration to uncover roles for the ubiquitin-proteasome system in the central nervous system. However, little is known about the effects of chemical proteasome inhibitors on retinal integrity. Therefore, we characterized the...
Main Authors: | Masaaki Kageyama, Takashi Ota, Masaaki Sasaoka, Osamu Katsuta, Katsuhiko Shinomiya |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0217945 |
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