Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures
The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited proliferation of cancer cells. To assess the potential of a compound as a telomerase inhibitor, selectivity for quadruple...
Main Authors: | Catarina I. V. Ramos, Susana P. Almeida, Leandro M. O. Lourenço, Patrícia M. R. Pereira, Rosa Fernandes, M. Amparo F. Faustino, João P. C. Tomé, Josué Carvalho, Carla Cruz, M. Graça P. M. S. Neves |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-02-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/24/4/733 |
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