Absence of CSF-1-Dependent Macrophages Does Not Improve Function of Transplanted Islets of Langerhans

Absence of CSF-1-Dependent Macrophages Does Not Improve Function of Transplanted Islets of Langerhans

A role of macrophage-mediated inflammatory events in early islet graft loss is increasingly acknowledged. Osteopetrotic mice (op/op) have a complete absence of CSF-1, and thus of most tissue macrophages. We have investigated whether the absence of CSF-1-dependent macrophages in the graft itself or a...

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Bibliographic Details
Main Authors: Thierry Berney, R. Damaris Molano, Antonello Pileggi, Pierre Cattan, Caterina Vizzardelli, Camillo Ricordi, Luca Inverardi M.D.
Format: Article
Language:English
Published: SAGE Publishing 2001-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000001783986341

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