DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

Abstract Background Environmental pollution induces oxidative stress and apoptosis in mammalian oocytes, which can cause defects in reproduction; however, the molecular regulation of oxidative stress in oocytes is still largely unknown. In the present study, we identified that dynamin-related protei...

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Bibliographic Details
Main Authors: Haolin Zhang, Zhennan Pan, Jiaqian Ju, Chunhua Xing, Xiaohan Li, Mengmeng Shan, Shaochen Sun
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Apoptosis
Meiosis
Mitochondria
Oocyte
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s40104-020-00489-4

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http://link.springer.com/article/10.1186/s40104-020-00489-4

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