Phosphatidylserine decarboxylase is critical for the maintenance of skeletal muscle mitochondrial integrity and muscle mass

Objective: Phosphatidylethanolamine (PtdEtn) is a major phospholipid in mammals. It is synthesized via two pathways, the CDP-ethanolamine pathway in the endoplasmic reticulum and the phosphatidylserine (PtdSer) decarboxylase (PSD) pathway in the mitochondria. While the CDP-ethanolamine pathway is co...

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Bibliographic Details
Main Authors: Ahrathy Selathurai, Greg M. Kowalski, Shaun A. Mason, Damien L. Callahan, Victoria C. Foletta, Paul A. Della Gatta, Angus Lindsay, Steven Hamley, Gunveen Kaur, Annie R. Curtis, Micah L. Burch, Teddy Ang, Sean L. McGee, Clinton R. Bruce
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877819302698